Zobrazeno 1 - 3
of 3
pro vyhledávání: '"J.Dean Farmer"'
Publikováno v:
Nucleic Acids Research. 19:899-903
We have investigated the DNA binding properties of the anthramycin analogues 4, 5, and 6 using fluorescence spectroscopy. A considerable fluorescence enhancement occurs when pyrrolo [1,4] benzodiazepines (P[1,4]Bs) are covalently attached to duplex D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e78e9a5161bce9386314529ef291f812
https://doi.org/10.1093/nar/19.4.899
https://doi.org/10.1093/nar/19.4.899
Publikováno v:
Tetrahedron Letters. 29:5105-5108
Linked analogs of the DNA binding antibiotic anthramycin are made via nucleophilic aromatic substitution followed by reduction-cyclization. The linked compounds protect DNA from restriction endonucleases and reversibly crosslink DNA.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5133129dd933bbdc356ada20cfa84ec3
https://doi.org/10.1016/s0040-4039(00)80691-7
https://doi.org/10.1016/s0040-4039(00)80691-7
Publikováno v:
Nucleic Acids Research; 2/15/1991, Vol. 19 Issue 4, p899-903, 5p