Zobrazeno 1 - 10
of 268
pro vyhledávání: '"J.D. Leander"'
Autor:
Craig R. Salhoff, Rebecca A. Wright, D D Schoepp, A.J. Palmer, David Bleakman, Joseph P. Tizzano, David M. Lodge, Paul L. Ornstein, J.D. Leander
Publikováno v:
Neuropharmacology. 34:1159-1168
The in vitro and in vivo pharmacology of a structurally novel competitive antagonist for the alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) subtype of excitatory amino acid receptors is described. LY215490, (+/-)(6-(2-(1-H-tetrazol-
Autor:
M.J., Benvenga, J.D., Leander
Publikováno v:
Behavioural pharmacology. 7(6)
Anxiety is a phenomenon that has many different manifestations. In order to test whether or not agents targeted to treat anxiety may have the properties necessary to treat differing types of anxiety, we have studied a 8-OH DPAT, buspirone, LY228729,
Autor:
David B. Wainscott, Franklin Porter Bymaster, M.C. Wolff, David L. Nelson, David L. McKinzie, K. Knitwoski, Nicholas A. Moore, Carl D Overshiner, J.D. Leander
Publikováno v:
Schizophrenia Research. 60:119-120
Publikováno v:
European Journal of Pharmacology. 183:601-602
Autor:
J.D. Leander
Publikováno v:
European Neuropsychopharmacology. 6:52
Autor:
D.M. Zimmerman, J.S. Gidda, B.E. Cantrell, J.A. Werner, C.J. Parli, R.B. Franklin, P.C. Francis, J.R. Means, R.C. Pohland, J.D. Leander
Publikováno v:
Drugs of the Future. 19:1078
Publikováno v:
Drugs of the Future. 15:983
Autor:
P. McCleary, J.D. Leander
Publikováno v:
Neuropharmacology. 21:1337-1341
A dose of 40 mg/kg of meperidine (pethidine) caused a marked lowering of rectal temperature in restrained female rats at room temperature (22°C). This decrease was not antagonized by injection of 1 mg/kg of naloxone. whereas hypothermia of equal mag
Autor:
D. E. McMillan, J.D. Leander
Publikováno v:
Pharmacology Biochemistry and Behavior. 5:195-200
A pattern of schedule-induced polydipsia was maintained in rats by a fixed-time schedule where food pellets were presented every 90 sec, a fixed-interval schedule where licking the drinking tube produced pellets every 90 sec, or a fixed-interval sche
Publikováno v:
Neuropharmacology. 27:623-628
The drug 4-amino-N-(2,6-dimethylphenyl)benzamide(LY201116) is a potent and selective anticonvulsant in the maximal electric shock test in mice. The ED50 values after oral and intravenous administration were 1.7mg/kg and 0.51 mg/kg, respectively. For