Zobrazeno 1 - 10
of 69
pro vyhledávání: '"J.C. Lormeau"'
Autor:
A Bernat, D.G. Meuleman, C. A. A. Van Boeckel, J.M. Herbert, J. P. Herault, M Petitou, J.C. Lormeau, Peter R. Hoffmann, van Rgm Amsterdam
Publikováno v:
Blood : the Journal of Hematology, 91(11), 4179-4205. American Society of Hematology
SANORG 34006 is a new sulfated pentasaccharide obtained by chemical synthesis. It is an analog of the “synthetic pentasaccharide” (SR 90107/ ORG 31540) which represents the antithrombin (AT) binding site of heparin. SANORG 34006 showed a higher a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a595b9874c2713ce116b1abf796b384b
https://doi.org/10.1182/blood.v91.11.4197
https://doi.org/10.1182/blood.v91.11.4197
Autor:
R. G. M. Van Amsterdam, J.P. He´rault, G.M.T. Vogel, D.G. Meuleman, M. Petitou, J.C. Lormeau, A. Bernat, J.M. Herbert
Publikováno v:
Circulation Research. 79:590-600
SANORG 32701 is a new sulfated pentasaccharide obtained by total chemical synthesis. It is an analogue of the “synthetic pentasaccharide” (SR 90107/ORG 31540), which represents the antithrombin III (AT-III) binding site of heparin. Like SR 90107,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ecbc9071b7c42a66f674a1806028129
https://doi.org/10.1161/01.res.79.3.590
https://doi.org/10.1161/01.res.79.3.590
Autor:
Rudi Pauwels, Masanori Baba, J.C. Lormeau, Myriam Witvrouw, M. Level, Tereza Barzu, Erik De Clercq, Maurice Petitou, Dominique Schols, Jean Choay
Publikováno v:
Journal of Medicinal Chemistry. 36:3546-3555
In order to increase the ratio of anti-HIV activity to anticoagulant activity, glycosaminoglycan derivatives selectively substituted at OH and/or COOH groups were prepared. Standard heparin, heparin fragments, or dermatan sulfate were converted to th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06afb969d86b6ce3089c7ad5f1ddd66d
https://doi.org/10.1021/jm00075a009
https://doi.org/10.1021/jm00075a009
Autor:
F. Dol, C. Caranobe, Maurice Petitou, Pierre Sie, Sylvie Saivin, Georges Houin, Bernard Boneu, J.C. Lormeau
Publikováno v:
Thrombosis Research. 66:527-535
In order to improve the pharmacokinetic properties of unfractionated dermatan sulfate (UDS, mean MW:25kD), the disposition of 4 low molecular weight dermatan sulfates (LMWDS) with a mean MW ranging from 15 to 4 kD was investigated in the rabbit. In c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d03318009a46b97e6cbf07b32636646
https://doi.org/10.1016/0049-3848(92)90307-v
https://doi.org/10.1016/0049-3848(92)90307-v
Publikováno v:
Scopus-Elsevier
Thrombosis and Haemostasis, 67(1), 33-41. Georg Thieme Verlag
Thrombosis and Haemostasis, 67(1), 33-41. Georg Thieme Verlag
SummaryThree fractions of the low molecular weight heparin CY216 (fraxiparin, mean molecular weight [MMW] 5,090), with MMWs of respectively, 3,090, 4,400 and 7,910 were prepared by gel permeation chromatography. From CY222 (MMW 3,770) as well as from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8c3d80c4557810208cb30a80d52a449
https://doi.org/10.1055/s-0038-1648375
https://doi.org/10.1055/s-0038-1648375
Autor:
Jean Pascal Herault, Teresa Barzu, Jean Marc Herbert, Colette Gaich, Theo G. van Dinther, J.C. Lormeau, A. Visser
Publikováno v:
Thrombosis research. 85(1)
The anti-factor Xa activity of the synthetic pentasaccharide SR 90107A/ORG 31540 was assayed by a chromogenic method at pH 8.4 and pH 7.35, comparatively to the 4th International Heparin Standard (IHS) or to the Ist International Low Molecular Weight
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06b0bd8040a4dd72e5a2fd15afa35ac0
https://pubmed.ncbi.nlm.nih.gov/8983127
https://pubmed.ncbi.nlm.nih.gov/8983127
Publikováno v:
Journal of pharmaceutical sciences. 84(6)
The recently proposed calibrant LHN‐1 (lot F537; henceforth designated F537), for the molecular weight (MW) determination by high‐performance size‐exclusion chromatography of heparins, is shown here to have a range too narrow to allow for the a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::075bdfd9acfb171b42f45869f779a99e
https://pubmed.ncbi.nlm.nih.gov/7562412
https://pubmed.ncbi.nlm.nih.gov/7562412
Publikováno v:
Seminars in thrombosis and hemostasis. 21(2)
To investigate AT-III affinity dependence on heparin's actions, heparin (UH) was fractionated on an AT-III-Sepharose column into a high (HAH) and a low affinity (LAH) fraction. Molecular profiling revealed a molecular weight of 11.8 kDa for (UH), 12.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38ee4ed8250c039ea725078164c33fc4
https://pubmed.ncbi.nlm.nih.gov/7660142
https://pubmed.ncbi.nlm.nih.gov/7660142
Autor:
Marc Delarue, Jean-Pierre Samama, Maurice Petitou, Jean Choay, Dino Moras, J.C. Lormeau, Lionel Mourey
Publikováno v:
Biochimie
Biochimie, Elsevier, 1990, 72 (8), pp.599-608. ⟨10.1016/0300-9084(90)90123-x⟩
Biochimie, Elsevier, 1990, 72 (8), pp.599-608. ⟨10.1016/0300-9084(90)90123-x⟩
International audience; Antithrombin Ill is a plasma glycoprotein responsib!e for thrombin inhibition in the blood coagulation cascade. The X-ray structure of its cleaved form has been determined and refined to 3.2 A resolution. The overall topology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47241878ad9e2a48808cdd5385844431
https://pubmed.ncbi.nlm.nih.gov/2126464
https://pubmed.ncbi.nlm.nih.gov/2126464
Autor:
Benito Casu, P Oreste, J.C. Lormeau, Giangiacomo Torri, Maurice Petitou, Jean Choay, Giuseppe Gatti, Pierre Sinaÿ
Publikováno v:
Thrombosis Research. 18:573-578
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b06ff648aecac6f1588cbbbd1f244b2
https://doi.org/10.1016/0049-3848(80)90356-4
https://doi.org/10.1016/0049-3848(80)90356-4