Zobrazeno 1 - 10
of 45
pro vyhledávání: '"J.A.H. Cognet"'
Publikováno v:
Journal of Molecular Biology. 268:331-347
The DNA duplexes 5' d(GCCACCAGCTC) x d(GAGCTXGTGGC), where the base X is either cytosine or thymine, have been studied by one and two-dimensional nuclear magnetic resonance, energy minimization and molecular dynamics. The sequence studied corresponds
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ef1351cd3c12cceac70a9ce59efe999
https://doi.org/10.1006/jmbi.1997.0975
https://doi.org/10.1006/jmbi.1997.0975
Autor:
Marc Le Bret, Corinne Gauthier, Jiří Kozelka, Karel Zimmermann, Eric Guittet, Marie-Hélène Fouchet, J.A.H. Cognet, Jean-Claude Chottard
Publikováno v:
JBIC Journal of Biological Inorganic Chemistry. 2:83-92
The structure of the second major adduct formed by the antitumor drug cisplatin with DNA, the intrastand cis–Pt(NH3)2{d(ApG)N7–N7} chelate (A*G*), has been investigated using a double-stranded nonanucleotide, d(CTCA*G*CCTC)-d(GAGGCTGAG), by means
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e8a897aa4a096faec9253691fd9d8531
https://doi.org/10.1007/s007750050109
https://doi.org/10.1007/s007750050109
Publikováno v:
European Journal of Biochemistry. 228:279-290
Two mismatches, one homopurine (A.A) and the other homopyrimidine (T.T), have been incorporated at the central position N of: 5'd(GCCACNAGCTC).d(GAGCTNGTGGC) in order to study nuclear magnetic resonance spectra and molecular dynamics. These duplexes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e54d7cd927c269b8a80192329f5c001
https://doi.org/10.1111/j.1432-1033.1995.0279n.x
https://doi.org/10.1111/j.1432-1033.1995.0279n.x
Publikováno v:
Journal of Molecular Biology. 246:194-208
The DNA duplex 5′ d(GCCACCAGCTC)-d(GAGCTGGTGGC) corresponds to the sequence 29 to 39 of the K- ras gene, which contains a hot spot for mutations. This has been studied by one and two-dimensional nuclear magnetic respnance, energy minimization and m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d7ac24c0890b9c19376a4269b668398
https://doi.org/10.1006/jmbi.1994.0076
https://doi.org/10.1006/jmbi.1994.0076
Publikováno v:
Journal of Molecular Biology. 246:209-226
We have analysed and compared the molecular structures and dynamics of the DNA duplex, that corresponds to the sequence 29 to 39 of the K-ras gene, where the central base-pair is the normal C.G base or a mismatch base-pair C.A, C.A+, A.G and A+.G. Mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bc248caf8ccb5a445c6d35f55b0dfd5
https://doi.org/10.1006/jmbi.1994.0077
https://doi.org/10.1006/jmbi.1994.0077
Publikováno v:
Biophysical Chemistry. 50:323-343
We present here a database of 32 deoxyribonucleotide triplets, that can be used as building blocks of triple helix forming deoxyribonucleotides on a computer. This database is made of all the pairing schemes of the triplets ATT, GCC+, ATA and GCG whe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a8a1e0e6fae0806d39fa42c3d31e023
https://doi.org/10.1016/0301-4622(93)e0103-c
https://doi.org/10.1016/0301-4622(93)e0103-c
Publikováno v:
Journal of Molecular Graphics. 10:166-173
We have written a programming language OCL (Object Command Language) to solve, in a general way, two recurring problems that arise during the construction of molecular models and during the geometrical characterization of macromolecules: how to move
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::017695dfe58757695f428531faaa5e58
https://doi.org/10.1016/0263-7855(92)80051-e
https://doi.org/10.1016/0263-7855(92)80051-e
Autor:
A. Guy, W. Guschlbauer, J. Gabarro-Arpa, M. Le Bret, Yves Boulard, Robert Teoule, J.A.H. Cognet, G. V. Fazakerley
Publikováno v:
Nucleic Acids Research. 19:5159-5167
We have determined by two-dimensional nuclear magnetic resonance studies and molecular mechanics calculations the three-dimensional solution structure of a 21 residue oligonucleotide capable of forming a hairpin structure with a loop of three thymidi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::357f951705f44ec6cb7a983a4e0b2bde
https://doi.org/10.1093/nar/19.19.5159
https://doi.org/10.1093/nar/19.19.5159
Publikováno v:
Journal of Biomolecular Structure and Dynamics. 7:1095-1115
In a previous publication (Ph. Cuniasse, L.C. Sowers, R. Eritja, B. Kaplan, M.F. Goodman, J.A.H. Cognet, M. Le Bret, W. Guschlbauer and G.V. Fazakerley, Biochemistry 28, 2018 (1989), we determined by two dimensional NMR studies and molecular mechanic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2028bcacc578c365df36c24707b7053
https://doi.org/10.1080/07391102.1990.10508549
https://doi.org/10.1080/07391102.1990.10508549
Autor:
J.A.H. Cognet, J. Gabarro-Arpa, Lawrence C. Sowers, M. Le Bret, G. V. Fazakerley, Yves Boulard
Publikováno v:
Nucleic acids research. 20(8)
The structure of the cytosine-adenine mispair in a 7 base pair duplex has been investigated by proton NMR spectroscopy. At low pH, the predominant structure is protonated on the A residue and assumes a wobble conformation consistent with previous fin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca9886fc2df2b2bf5f0b2de3597353c5
https://pubmed.ncbi.nlm.nih.gov/1579495
https://pubmed.ncbi.nlm.nih.gov/1579495