Výsledky vyhledávání - "J.A.G.M. Kleuskens"

Discovery of a recombinant Babesia canis supernatant antigen that protects dogs against virulent challenge infection

Autor: T. Van Kasteren, B. Carcy, Stephane Delbecq, Th.P.M. Schetters, J.A.G.M. Kleuskens, J. van de Crommert, K. Moubri, N.C. Scholtes, Eric Precigout, André Gorenflot

Publikováno v: Veterinary Parasitology
Veterinary Parasitology, Elsevier, 2018, 249, pp.21-29. ⟨10.1016/j.vetpar.2017.11.002⟩

Soluble parasite antigens (SPA) in supernatants of in vitro cultures of Babesia canis can be used to vaccinate dogs against virulent B. canis infection. The moment that immunity becomes apparent coincides with the appearance of antibodies against SPA

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e2fa5e245756006a0ae4a0722ea65cd
https://hal.umontpellier.fr/hal-01656922

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A new method for in vitro feeding of Rhipicephalus australis (formerly Rhipicephalus microplus) larvae: a valuable tool for tick vaccine development

Autor: J.A.G.M. Kleuskens, Theo Schetters, Jos van de Crommert, Jos J. A. Trentelman

Publikováno v: Parasites & Vectors
Parasites & vectors, 10(1). BioMed Central

Background Rhipicephalus microplus is a hard tick that has a major impact on cattle health in tropical and subtropical regions because it feeds on cattle and is implicated in the transmission of pathogens that cause diseases such as bovine anaplasmos

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7da092f326ea2bf550ed8803f18434c
https://doi.org/10.1186/s13071-017-2081-0

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Soluble parasite antigens from Babesia canis do not directly activate the kallikrein system in dogs infected with Babesia canis

Autor: A.-L. Finizio, J. van de Crommert, B. Carcy, J.A.G.M. Kleuskens, André Gorenflot, Th.P.M. Schetters

Publikováno v: Veterinary Parasitology. 176:132-138

Soluble parasite antigens (SPA) from Babesia canis have been shown to induce protective immunity when used as vaccine. In order to explain the immune mechanisms of vaccination, the precise role of SPA in the pathogenesis of canine babesiosis is under

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3277c6a603654206c23ab07e556b5d2
https://doi.org/10.1016/j.vetpar.2010.11.005

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Systemic inflammatory responses in dogs experimentally infected with Babesia canis; a haematological study

Autor: A.-L. Finizio, P.W.J. De Leeuw, André Gorenflot, J. van de Crommert, J.A.G.M. Kleuskens, Th.P.M. Schetters

Publikováno v: Veterinary Parasitology. 162:7-15

A detailed haematological study of dogs that were infected with low, moderate or high numbers of Babesia canis-infected red blood cells was performed in an attempt to elucidate the pathogenesis early after B. canis infection. Results showed that upon

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83e3916c87db49147c1c89d76821ae1a
https://doi.org/10.1016/j.vetpar.2009.02.012

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Onset and duration of immunity against Babesia canis infection in dogs vaccinated with antigens from culture supernatants

Autor: A.N. Vermeulen, K. Moubri, J.A.G.M. Kleuskens, J. van de Crommert, E. Krijnen, N.C. Scholtes, André Gorenflot, Theo Schetters

Publikováno v: Veterinary Parasitology. 138:140-146

It has previously been shown that dogs can be vaccinated against heterologous Babesia canis infection using a vaccine containing soluble parasite antigens (SPA) from in vitro cultures of B. canis and B. rossi that are adjuvanted with saponin. In the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::808d113937b9a9553e0eb4d6392a4dc7
https://doi.org/10.1016/j.vetpar.2006.01.049

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Different Babesia canis isolates, different diseases

Autor: N.C. Scholtes, Eric Precigout, K. Moubri, Th. P. M. Schetters, André Gorenflot, J.A.G.M. Kleuskens

Publikováno v: Parasitology. 115:485-493

Using surface immunofluorescence isolate-specific antigens were detected on the membrane of erythrocytes infected with Babesia parasites. In addition, the strains reacted differently with Plasmagel in that the European isolate (B.c. canis) could be p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1004c1eed5a4648a19a9e852a8b4344d
https://doi.org/10.1017/s0031182097001686

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Not peripheral parasitaemia but the level of soluble parasite antigen in plasma correlates with vaccine efficacy against Babesia canis

Autor: H.J. Bos, Th.P.M. Schetters, J.A.G.M. Kleuskens, N.C. Scholtes

Publikováno v: Parasite Immunology. 18:1-6

Groups of five dogs were vaccinated against Babesia canis using soluble parasite (SPA) antigens from in vitro cultures. Although vaccination did not significantly alter peripheral parasitaemia upon challenge, protected animals had lower levels of SPA

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96cee6742e654bc2bb0976bf74eb2679
https://doi.org/10.1046/j.1365-3024.1996.d01-1.x

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Vaccination of dogs against Babesia canis infection using antigens from culture supernatants with emphasis on clinical babesiosis

Autor: Th.P.M. Schetters, N.C. Scholtes, J.A.G.M. Kleuskens, H.J. Bos, J.W. Pasman

Publikováno v: Veterinary Parasitology. 52:219-233

Groups of five dogs were vaccinated with Babesia canis antigens from in vitro culture in combination with saponin as adjuvant. Protection against challenge infection was evident as diminished clinical disease, decrease in parasitaemia, and a less mar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1e25dabfbe510f6f393010238fafb24
https://doi.org/10.1016/0304-4017(94)90114-7

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Immunity against Babesia rossi infection in dogs vaccinated with antigens from culture supernatants

Autor: D. Crafford, J. van de Crommert, A.N. Vermeulen, Th.P.M. Schetters, T. Strydom, J.A.G.M. Kleuskens

Publikováno v: Veterinary parasitology. 144(1-2)

Soluble parasite antigens (SPA) from different Babesia species have been shown earlier to induce protective immunity when used as vaccine. However, initial attempts to produce such vaccine against Babesia rossi infection using SPA from B. rossi cultu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::591de861a1276eb14051ca4d2f92a9d4
https://pubmed.ncbi.nlm.nih.gov/17056181

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