Zobrazeno 1 - 10
of 69
pro vyhledávání: '"J.A. Zijlstra"'
Publikováno v:
Toxicology in vitro : an international journal published in association with BIBRA. 7(6)
A comparative study was performed to assess the effects of six pairs of coded compounds using cultures of whole chick and rat embryos as well as aggregating brain cell cultures. Developed originally for basic studies in developmental biology, these t
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 44:257-267
The presence of cytochrome P-450 and aryl hydrocarbon hydroxylase activity in microsomes prepared from three strains of Drosophila melanogaster was investigated. The first microsomal preparations, for which mortar pounding was used to homogenize the
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 110:59-70
The sensitivity of male germ cells of ebony (UV and X-ray sensitive) and Canton-S (wild-type) flies to the induction of sex-linked recessive lethals by 3 direct-acting mutagens (methyl methanesulphonate (MMS), N-ethyl-N-nitrosourea (ENU) and 1,2:3,4-
Autor:
E.W. Vogel, J.A. Zijlstra
Publikováno v:
Mutation Research/Environmental Mutagenesis and Related Subjects. 182:243-264
This study presents the analysis of chemically-induced somatic mutations and chromosomal damage in the eye imaginal discs of Drosophila larvae, assayed later as twin (TS) and single light (LS) mosaic spots in the adult eyes. Regarding the question as
Autor:
J.A. Zijlstra
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 210:255-261
The induction by some cross-linking agents of forward mutations leading to nalidixic acid resistance in Escherichia coli K12/343/113 was considerably enhanced when a 24-h period of liquid holding was interpolated between treatment and growth phase. L
Autor:
Ekkehart W. Vogel, J.A. Zijlstra
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 210:79-92
This paper describes the influence of changes in metabolic activity on the in-vivo mutagenic effectiveness of cyclophosphamide in Drosophila melanogaster. A dose-dependent increase in mutagenicity was observed until a plateau value is reached which w
Autor:
J.A. Zijlstra, Ekkehart W. Vogel
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 125:243-261
The optimal conditions for mutagenesis studies with DMBA and some other aromatic carcinogens in Drosophila were investigated in detail. The results presented in this paper indicate the following. The mutagenic effectiveness of DMBA is dependent on th
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 212:193-211
The mutagenic profiles in Drosophila and the influence of inhibition of metabolism on genotoxic activity were determined for hexamethylphosphoric triamide (HMPA), some synthetically prepared presumed metabolites and ethylated analogs. Demethylated HM