Zobrazeno 1 - 10
of 758
pro vyhledávání: '"J.A. Wood"'
Autor:
Britt Hanson, Ioulia Vorobieva, Wenyi Zheng, Mariana Conceição, Yulia Lomonosova, Imre Mäger, Pier Lorenzo Puri, Samir El Andaloussi, Matthew J.A. Wood, Thomas C. Roberts
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 33, Iss , Pp 511-528 (2023)
Extracellular vesicles (EVs) have been implicated in the regulation of myogenic differentiation. C2C12 murine myoblast differentiation was reduced following treatment with GW4869 or heparin (to inhibit exosome biogenesis and EV uptake, respectively).
Externí odkaz:
https://doaj.org/article/dbfffb011eea4b189072c8015fdf36f1
Autor:
Suzan M. Hammond, Frank Abendroth, Larissa Goli, Jessica Stoodley, Matthew Burrell, George Thom, Ian Gurrell, Nina Ahlskog, Michael J. Gait, Matthew J.A. Wood, Carl I. Webster
Publikováno v:
JCI Insight, Vol 7, Iss 24 (2022)
Antisense oligonucleotides (ASOs) have emerged as one of the most innovative new genetic drug modalities. However, their high molecular weight limits their bioavailability for otherwise-treatable neurological disorders. We investigated conjugation of
Externí odkaz:
https://doaj.org/article/e10b5264221549b9be42dfc52acf597f
Autor:
Meiyang Yang, Mariana Conceição, Weijun Chen, Fuwei Yang, Bingke Zhao, Matthew J.A. Wood, Lipeng Qiu, Jinghua Chen
Publikováno v:
Acta Biomaterialia. 158:734-746
Methods capable of distributing antitumour therapeutics uniformly throughout an entire tumour and that can suppress metastasis at the same time, would be of great significance in improving cancer treatment. Bacteria-mediated synergistic therapies hav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3d7448eaa0457a0b6141930843466d1
https://doi.org/10.1016/j.actbio.2022.12.027
https://doi.org/10.1016/j.actbio.2022.12.027
Autor:
Chao Deng, Yiwei Hu, Mariana Conceição, Matthew J.A. Wood, Hongyao Zhong, Yan Wang, Ping Shao, Jinghua Chen, Lipeng Qiu
Publikováno v:
Journal of Controlled Release. 354:635-650
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::57cf2eb254692159ac1f88dc1d1f1943
https://doi.org/10.1016/j.jconrel.2023.01.017
https://doi.org/10.1016/j.jconrel.2023.01.017
Publikováno v:
Extracellular Vesicles and Circulating Nucleic Acids. 4:170-90
The field of extracellular vesicles (EVs) has seen a tremendous paradigm shift in the past two decades, from being regarded as cellular waste bags to being considered essential mediators in intercellular communication. Their unique ability to transfe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b55062c4fe57e754a48dfde9ca3b57ff
https://doi.org/10.20517/evcna.2023.12
https://doi.org/10.20517/evcna.2023.12
Autor:
Anna M.L. Coenen-Stass, Helena Sork, Sole Gatto, Caroline Godfrey, Amarjit Bhomra, Kaarel Krjutškov, Jonathan R. Hart, Jakub O. Westholm, Liz O’Donovan, Andreas Roos, Hanns Lochmüller, Pier Lorenzo Puri, Samir EL Andaloussi, Matthew J.A. Wood, Thomas C. Roberts
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 13, Iss , Pp 1-15 (2018)
Extracellular small RNAs (sRNAs), including microRNAs (miRNAs), are promising biomarkers for diseases such as Duchenne muscular dystrophy (DMD), although their biological relevance is largely unknown. To investigate the relationship between intracell
Externí odkaz:
https://doaj.org/article/dc55244590fd44329400bbee0db3a420
Autor:
Katarzyna Chwalenia, Jacopo Oieni, Joanna Zemła, Małgorzata Lekka, Nina Ahlskog, Anna M.L. Coenen-Stass, Graham McClorey, Matthew J.A. Wood, Yulia Lomonosova, Thomas C. Roberts
Publikováno v:
Molecular Therapy - Nucleic Acids. 29:955-968
Therapies that restore dystrophin expression are presumed to correct Duchenne muscular dystrophy (DMD), with antisense-mediated exon skipping being the leading approach. Here we aimed to determine whether exon skipping using a peptide-phosphorodiamid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e47664f37750961bbc66d53ae1356845
https://doi.org/10.1016/j.omtn.2022.08.033
https://doi.org/10.1016/j.omtn.2022.08.033
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