Zobrazeno 1 - 10 of 91 pro vyhledávání: '"J.A. Poat"'
1
The anxiolytics CI-988 and chlordiazepoxide fail to reduce immediate early gene mRNA stimulation following exposure to the rat elevated X-maze
Autor: Pierre Brown, Gillian L. Hinks, John Hughes, J.A. Poat, Mark J. Field
Publikováno v: European Journal of Pharmacology. 312:153-161
This study uses immediate early transcription factor gene expression to map neuronal activation after a single exposure to the elevated X-maze. Exposure to this novel environment leads to widespread upregulation in the gene expression of c-fos, NGFI-
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e67df271333d2e5469ddf6be882578ac
https://doi.org/10.1016/0014-2999(96)00471-2
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2
Changes in hypothalamic cholecystokininA and cholecystokininB receptor subtypes and associated neuropeptide expression in response to salt-stress in the rat and mouse
Autor: J.A. Poat, G.L. Hinks, John Hughes
Publikováno v: Neuroscience. 68(3)
This study demonstrates cholecystokinin receptor plasticity in response to salt-loading in the rat and mouse hypothalamus. It identifies, for the first time, the cholecystokinin receptor subtypes involved, firstly by receptor autoradiography and seco
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97f17fceaef49c53423993c46df83165
https://pubmed.ncbi.nlm.nih.gov/8577372
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3
c-fos antisense oligodeoxynucleotide increases formalin-induced nociception and regulates preprodynorphin expression
Autor: J.A. Poat, J.C. Hunter, V.L. Woodburn, John Hughes, E.K.E. Pettersson, C. Durieux
Publikováno v: Neuroscience. 65(2)
Rats, receiving an intrathecal pretreatment of oligodeoxynucleotide complementary to c- fos mRNA (antisense), showed no increases in Fos protein or preprodynorphin messenger RNA in the outer laminae of the lumbar spinal cord when challenged 4 h later
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e71ba46944132c2e6ed1f172cbe76a9a
https://pubmed.ncbi.nlm.nih.gov/7777163
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4
Evidence that cholecystokinin induces immediate early gene expression in the brainstem, hypothalamus and amygdala of the rat by a CCKA receptor mechanism
Autor: J.A. Poat, Heidi E.W. Day, A.T. Mcknight, John Hughes
Publikováno v: Neuropharmacology. 33(6)
The effect of sulphated cholecystokinin octapeptide (CCK-8S) on immediate early gene expression in the rat CNS was investigated using the technique of in situ hybridization. A rapid and transient induction of c-fos, NGFI-A and NGFI-B (nerve growth fa
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71129dd3d190734ca2f94af99249da8b
https://pubmed.ncbi.nlm.nih.gov/7936109
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5
The effect of dizocilpine and enadoline on immediate early gene expression in the gerbil global ischaemia model
Autor: Geoffrey N. Woodruff, J.A. Poat, Valerie L. Woodburn, Neil J. Hayward, John Hughes
Publikováno v: Neuropharmacology. 32(10)
Increases in mRNA levels for c-fos, c-jun, junB, hsp 70 and NGFI-A were observed in the dentate gyrus of the hippocampus following 7 min ischaemia in the Mongolian gerbil. The response was rapid and transient (30 min to 4hr) for NGFI-A, junB and c-fo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6926d127b3624ecd8e00b153e4047b05
https://pubmed.ncbi.nlm.nih.gov/8295713
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6
Anticonvulsant agents, dizocilpine maleate, enadoline and HA 966 have different effects on N-methyl-DL-aspartate-induced immediate early gene induction in mice
Autor: John Hughes, J.A. Poat, Geoffrey N. Woodruff, Ryszard J. Oles, V.L. Woodburn
Publikováno v: Neuroscience. 56(3)
Administration of N-methyl- dl -aspartate (85 mg/ml) was given by infusion (0.14ml/min) until a clonic seizure was elicited. In situ hybridization was used to assess regional levels of four immediate early gene messenger RNA levels (c- fos , c- jun ,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c10dafd8bcaccd1b2ac09a3cc1ccbf21
https://pubmed.ncbi.nlm.nih.gov/8255428
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10
The effect of dietary morfamquat on mitochondrial function in rat kidney
Autor: J.A. Poat, D. Morris, Kenneth A. Munday
Publikováno v: International Journal of Biochemistry. 3:378-382
1. 1. Mitochondria, prepared from the medullary-papillary region of kidneys from male adult rats which had been fed with a low (0.015 per cent) dietary concentration of morfamquat dichloride for 18–20 weeks, were functionally examined. 2. 2. Respir
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1e59b559a1332506729bea465b662053
https://doi.org/10.1016/0020-711x(72)90087-0
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