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Publikováno v:
Bone Marrow Transplantation. 51:1612-1614
Publikováno v:
Cytotherapy. 11:35-42
Hematopoietic progenitor cells (HPC) circulate at high levels at birth and disappear rapidly afterwards, but the underlying mechanism it is not known. The aim of this study was to assess circulating HPC in cord blood at different gestational ages and
Publikováno v:
Cirugía y Cirujanos. 84(4):267-268
Autor:
P. Hayden, G. Rooney, S. G. E. Marsh, Emer Lawlor, AM Little, J.A. Madrigal, D. Clancy, C. Dunne, Richard Hagan, John Crowley, B. Soteriou
Publikováno v:
Tissue Antigens. 61:487-491
HLA class II typing by sequence specific oligonucleotide probes (SSOP) on the family of a Burkit's Lymphoma patient produced hybridization patterns indicating the presence of two DRB1, and two linked DQB1 genes on the same maternal chromosome. DRB an
Autor:
James Robinson, Steven T. Cox, J.A. Madrigal, Sge Marsh, A-M. Little, A.J. McWhinnie, Peter Parham
Publikováno v:
Tissue Antigens. 61:20-48
Currently most available HLA-A, -B and -C DNA sequences cover exons 2 and 3 with a limited number extending to include other exons and introns. We have developed a method for the accurate determination of full-length genomic DNA sequences for HLA-A,
Publikováno v:
Tissue Antigens. 59:66-69
Sequencing studies of HLA class II molecules have been focused almost exclusively on the highly polymorphic exon 2. In this study the complete cDNA sequence of four alleles of the DR14 lineage (DR52 group) are reported for the first time. The HLA-DRB
Publikováno v:
Tissue Antigens. 56:188-191
Sequence analysis of HLA class I alleles has continued to reveal the true extent of polymorphism, particularly for B-locus alleles. This diversity can arise through reshuffling of polymorphic sequences generated by point mutation, resulting in intera
Autor:
J.A. Madrigal, Alfredo Corell, C. Dunne, Ann-Margaret Little, J.R. Argüello, M.A. Hoddinott, John J. O'Shea, H. Ogilvie, Sge Marsh, M. Borton, AL Pay
Publikováno v:
Tissue Antigens. 56:82-86
We show here the use of reference strand mediated conformation analysis (RSCA) to unambiguously resolve the HLA-DRB1 typing of two individuals which were selected as potential unrelated donors for bone marrow transplantation (BMT). In the first case,
Autor:
H. Ogilvie, Steven T. Cox, Sge Marsh, A.J. McWhinnie, Ann-Margaret Little, M.A. Hoddinott, J.A. Madrigal
Publikováno v:
Tissue Antigens. 55:463-466
Human HLA genes exhibit extreme polymorphism, the extent of which is emphasised by the identification of an ever increasing number of new alleles by DNA-based typing strategies. Here we describe a novel allele, belonging to the HLA-B*15 group, which