Zobrazeno 1 - 10
of 142
pro vyhledávání: '"J.A. Lowden"'
Autor:
J.A. Lowden
Publikováno v:
Clinica Chimica Acta. 93:409-417
Serum contains several hexosaminidase forms. Two, HEX A and HEX B, migrate in both DEAE cellulose and isoelectric focussing systems like their tissue counterparts. A major group of serum hexosaminidases migrate in an intermediate position. These form
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e385b4f15aad1f5bc04f59fb61356a1e
https://doi.org/10.1016/0009-8981(79)90292-4
https://doi.org/10.1016/0009-8981(79)90292-4
Autor:
J.A. Lowden
Publikováno v:
Journal of Chromatography A. 27:246-249
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b083af7b74150c96f35bedc699ee4bd4
https://doi.org/10.1016/s0021-9673(01)85859-3
https://doi.org/10.1016/s0021-9673(01)85859-3
Autor:
A.J. Wilensky, J.A. Lowden
Publikováno v:
Life Sciences. 11:319-327
Diphenylhydantoin (DPH) may act by affecting ATPase activity. Using equilibrium dialysis we have found that DPH has a high affinity for subcellular fractions rich in ATPases. This affinity is decreased by Ca ++ . The Ca ++ effect is prevented by Mg +
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ee12802b893ce81bea2d5dc63bd0efa
https://doi.org/10.1016/0024-3205(72)90085-9
https://doi.org/10.1016/0024-3205(72)90085-9
Publikováno v:
American journal of obstetrics and gynecology. 118(3)
In the past five years, rapid advances in the antenatal diagnosis of genetic disease have been made. In our center, an Amniotic Fluid Study Group has been formed for research in this area. In addition, an Antenatal Genetic Clinic with a multidiscipli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::194db268b02569955471fb613e68d7d5
https://pubmed.ncbi.nlm.nih.gov/4272472
https://pubmed.ncbi.nlm.nih.gov/4272472
Publikováno v:
Journal of the neurological sciences. 21(2)
This report describes morphologic changes in a 19-week saline-aborted fetus with Tay-Sachs disease (TSD, GM 2 gangliosidosis) diagnosed in utero and subsequently confirmed by biochemical and morphological studies of fetal tissues. Typical membranous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33bbcbe91e5a927f336dd622f0a47b33
https://pubmed.ncbi.nlm.nih.gov/4374514
https://pubmed.ncbi.nlm.nih.gov/4374514
Autor:
J.A. Lowden, P.M. Strasberg
Publikováno v:
Journal of chromatography. 261(3)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e03bb01cff9632a4e5ae4f872f191e6
https://pubmed.ncbi.nlm.nih.gov/6874804
https://pubmed.ncbi.nlm.nih.gov/6874804
Publikováno v:
The Journal of pediatrics. 104(2)
Neonatal ascites is usually attributed to hematologic, genitourinary, gastrointestinal tract, or congenital heart disease. When these lesions have been excluded, metabolic storage disorders should be considered in the differential diagnosis. We repor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5c39a96b81608d81b36379abac249c6
https://pubmed.ncbi.nlm.nih.gov/6420531
https://pubmed.ncbi.nlm.nih.gov/6420531
Publikováno v:
Clinica chimica acta; international journal of clinical chemistry. 132(1)
Concentrations of GL-la (glucocerebroside) (8.36 nmol/ml), GL-2a (lactosylceramide) (4.03 nmol/ml), GL-3a (globotriosylceramide) (2.25 nmol/ml) and GL-4a (globotetraosylceramide) (2.87 nmol/ml) have been determined in normal plasma and compared to co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96b94a612278448f3c62bf7b67f9296f
https://pubmed.ncbi.nlm.nih.gov/6616861
https://pubmed.ncbi.nlm.nih.gov/6616861
Publikováno v:
Clinica chimica acta; international journal of clinical chemistry. 113(1)
Tay-Sachs disease results from a loss of activity of hexosaminidase A (HEX A) in body tissues and fluids. Heterozygotes for the disease are usually identified by their relatively low ratio of heat-labile HEX A to total hexosaminidase. During pregnanc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b48a832d4d4736f2c67f4811fc459893
https://pubmed.ncbi.nlm.nih.gov/6453673
https://pubmed.ncbi.nlm.nih.gov/6453673
Autor:
J.A. Lowden, P.M. Strasberg
Publikováno v:
Clinica chimica acta; international journal of clinical chemistry. 118(1)
We examined eight published methods for the assay of glucocerebrosidase using the natural substrate glucocerebroside and tabulated the variable components and conditions while comparing these methods to ours. In each case assays were performed using
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fed65d6e39140ffb230ba37083ca5a4d
https://pubmed.ncbi.nlm.nih.gov/7053909
https://pubmed.ncbi.nlm.nih.gov/7053909