Zobrazeno 1 - 10
of 169
pro vyhledávání: '"J.-P. Macher"'
Autor:
Remy Luthringer, S. Gamand, L. Staner, C. Gilles, J.F. Nedelec, P.H. Boeijinga, M.L. Souan, J.-P. Macher, A. Demazières, P. Parot
Publikováno v:
Neuropsychobiology. 48:160-168
In the present study, we investigated the effects of a single and a repeated (5 days) administration of naftidrofuryl, a serotonin 5-HT2 receptor inhibitor having neuroprotective properties, on functional brain physiology in male healthy elderly subj
Autor:
A. Torres-Ruiz, A. Castillo, J. P. Macher, A. Lipcsey, R. Batista, L. Vergara, Eugenio Aguglia, P. Gaszner, Thomas A. Ban
Publikováno v:
Human Psychopharmacology: Clinical and Experimental. 13:S29-S39
The efficacy and tolerability of 4–8 mg reboxetine, a selective noradrenaline reuptake inhibitor (NARI) was verified in a 4-week, double-blind, placebo- and desipramine-controlled study in hospitalised patients with major depression. Two-hundred-an
Autor:
Alain Muzet, Alain Nicolas, Remy Luthringer, J.-P. Macher, N. Schaltenbrand, M. Toussaint, Julien Gresser, Gabriella Carelli, Anne Jacqmin
Publikováno v:
Sleep. 20:1201-1207
First- and second-night effects on the electroencephalogram (EEG) were investigated by means of polygraphic sleep recordings and all-night spectral analysis. Eighteen normal subjects were studied for three consecutive nights in a hospital sleep labor
Autor:
J.-P. Macher, M. Ackenheil
Publikováno v:
European Neuropsychopharmacology. 6:S4-22
Publikováno v:
Biological Cybernetics. 74:395-403
Studies on extended data including 37 electroencephalographic (EEC) records of delta-sleep, each 10(3) s long (six subjects: up to seven nights per subject, comprising normal sleep, partial deprivation and recovery), confirmed earlier conclusions tha
Publikováno v:
Journal of Biological Physics. 22:209-225
Attempts to demonstrate low-dimensional attractor behaviour in the analysis of electroencephalographic (EEG) signals meet with difficulties that in part stem from a departure from single-system dynamics. In order to address this problem, the α-waves
Autor:
Teresa Paiva, N. Schaltenbrand, R. Luthringer, C. Pflieger, Thomas Pollmächer, J.-P. Macher, M. Toussaint
Publikováno v:
Computer Methods and Programs in Biomedicine. 45:55-60
The project's aim is to develop a dedicated workstation in order to process multiple channels of electrophysiological signals in real-time during sleep. In ESPIS we are aiming to define both an architecture and an environment for EEG signal interpret
Publikováno v:
Computers and Biomedical Research
Computers and Biomedical Research, Elsevier-Academic Press;Elsevier, 1993, 26 (2), pp.157-171. ⟨10.1006/cbmr.1993.1010⟩
Computers and Biomedical Research, Elsevier-Academic Press;Elsevier, 1993, 26 (2), pp.157-171. ⟨10.1006/cbmr.1993.1010⟩
International audience; We describe an approach to automatic all-night sleep analysis based on neural network models and simulated on a digital computer. First, automatic sleep stage scoring was performed using a multilayer feedforward network. Secon
Autor:
J. P. Macher, P. Nuss, G. Reischl, A. Demazières, A. Hameg, M. Dib, Matthias Reimold, Franck Baylé, Y. Hodé
Publikováno v:
Psychopharmacology. 180(2)
Cyamemazine (Tercian) is an antipsychotic drug with anxiolytic properties. Recently, an in vitro study showed that cyamemazine possesses high affinity for serotonin 5-HT(2A) receptors, which was fourfold higher than its affinity for dopamine D(2) rec
Publikováno v:
Revue neurologique. 159
Most pharmacotherapeutic treatments designed to treat insomnia target GABAergic activity globally in the brain. Development of new molecules having a more specific activity pathway should improve treatment efficacy and acceptance. Both subjective and