Zobrazeno 1 - 10
of 23
pro vyhledávání: '"J.-P. Buono"'
Publikováno v:
Molecular Neurodegeneration, Vol 19, Iss 1, Pp 1-12 (2024)
Abstract The extracellular matrix is a richly bioactive composition of substrates that provides biophysical stability, facilitates intercellular signaling, and both reflects and governs the physiological status of the local microenvironment. The matr
Externí odkaz:
https://doaj.org/article/a207ceef47b64a0f8c77cf84dfe821bd
Autor:
Robert O. Baratta, MD, Eric Schlumpf, BS, Brian J. Del Buono, PhD, Shawn DeLorey, George Ousler, MS, David J. Calkins, PhD
Publikováno v:
Ophthalmology Science, Vol 4, Iss 3, Pp 100451- (2024)
Objective: Dry eye disease (DED) is a worldwide source of ocular discomfort. This first-in-human phase 2 clinical study determined the efficacy of treating signs and symptoms of DED using an ophthalmic solution of synthesized mimetic of human collage
Externí odkaz:
https://doaj.org/article/2b566e7fa1174ae4beb799f197880305
Autor:
Lauren K. Wareham, Joseph M. Holden, Olivia L. Bossardet, Robert O. Baratta, Brian J. Del Buono, Eric Schlumpf, David J. Calkins
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
The intraepithelial sub-basal nerve plexus of the cornea is characterized by a central swirl of nerve processes that terminate between the apical cells of the epithelium. This plexus is a critical component of maintaining homeostatic function of the
Externí odkaz:
https://doaj.org/article/9da9d9f7e3c24a5da3069e7c52b07094
Autor:
Nolan R. McGrady, Silvia Pasini, Robert O. Baratta, Brian J. Del Buono, Eric Schlumpf, David J. Calkins
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Optic neuropathies are a major cause of visual disabilities worldwide, causing irreversible vision loss through the degeneration of retinal ganglion cell (RGC) axons, which comprise the optic nerve. Chief among these is glaucoma, in which sensitivity
Externí odkaz:
https://doaj.org/article/44603aba52ad4a869be36e73567ce630
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
The cornea of the eye is at risk for injury through constant exposure to the extraocular environment. A highly collagenous structure, the cornea contains several different types distributed across multiple layers. The anterior-most layer contains non
Externí odkaz:
https://doaj.org/article/a50a50e3d7e14abc95eb44cbc5df44d1
Autor:
A. Chambelland, Philippe Berbis, E. Desmedt, J.-P. Buono, J. Fongue, Emmanuel Delaporte, M.-C. Koeppel
Publikováno v:
Annales de Dermatologie et de Vénéréologie. 146:646-654
Resume Introduction Le sorafenib est un inhibiteur multikinases utilise dans le traitement du carcinome hepatocellulaire, du carcinome renal a un stade avance et des carcinomes thyroidiens differencies. Ses effets secondaires cutanes sont multiples e
Publikováno v:
Annales de dermatologie et de venereologie. 146(10)
Sorafenib is a multikinase inhibitor used in the treatment of hepatocellular carcinoma, advanced renal cell carcinoma, and differentiated thyroid carcinoma. Cutaneous adverse events are numerous and occur frequently.We present two cases of nodulocyst
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Publikováno v:
Cell Biology and Toxicology. 13:193-204
Recent epidemiological studies have brought to light a possible link between premalignant or neoplastic skin lesions (Bowen disease, squamous carcinoma) and occupational exposure to 4,4′-bipyridyl (4,4′B), a precursor in the synthesis of paraquat
Autor:
M, d'Incan, M L, Mouillet, H, Roger, M C, Ferrier, J P, Buono, P, Déchelotte, Y J, Bignon, P, Souteyrand
Publikováno v:
Annales de dermatologie et de venereologie. 125(1)
Drug-induced cutaneous pseudolymphomas are poorly reported. They clinically and pathologically mimic malignant lymphomas but their evolution is benign after drug withdrawal.We herein reported a case of carbamazepine++-induced pseudolymphoma in a 30 y