Zobrazeno 1 - 10
of 45
pro vyhledávání: '"J.-N. Bidard"'
Publikováno v:
The Journal of biological chemistry. 276(9)
The mechanisms by which prohormone precursors are sorted to the regulated secretory pathway in neuroendocrine cells remain poorly understood. Here, we investigated the presence of sorting signal(s) in proneurotensin/neuromedin N. The precursor sequen
Publikováno v:
Neuroscience. 60(1)
Neurotensin and neuromedin N are two biologically active related peptides which are encoded in the same precursor molecule. In the rat, the precursor consists of a 169-residue polypeptide containing in its C-terminal region one copy each of neurotens
Publikováno v:
Journal of Biological Chemistry. 259:13957-13967
The preparation of a pure, monoiodinated derivative of mast cell-degranulating peptide (MCD peptide), the mast cell-degranulating peptide from bee venom, has enabled us to identify binding sites in rat brain membranes that have a high affinity and sp
Publikováno v:
Archives Internationales de Physiologie et de Biochimie. 87:253-264
1.—The administration of SAH to rats, at physiologically active dose on the sleep, does not change the urinary level of MD and NM. On the other hand, the excretion of DA and NA decreases.2.—In the brain, SAH does not modify neither the concentrat
Publikováno v:
Archives Internationales de Physiologie et de Biochimie. 86:715-724
The repartition of [3H]L-dopa administred i.p. does not change in rats treated with 5-adenosyl-L-methionine (SAM). The effect was studied on the central nervous system and at the periphery. The biosynthesis of metabolites [3H]dopamine and [3H]3-O-met
Publikováno v:
Archives internationales de physiologie et de biochimie. 87(2)
1.--The administration of SAH to rats, at physiologically active dose on the sleep, does not change the urinary level of MD and NM. On the other hand, the excretion of DA and NA decreases. 2.--In the brain, SAH does not modify neither the concentrati
Autor:
J N, Bidard, L, Cronenberger
Publikováno v:
Comptes rendus hebdomadaires des seances de l'Academie des sciences. Serie D: Sciences naturelles. 284(5)
A new method for the isolation and determination of 3-O-methyldopamine (3 MD) and 4-O-methyldopamine (4 MD) in the urine of Rat has been described. The administration of L-dopa enabled us to detect 4 MD in the urine with a molar ratio 4 MD/3 MD = 0.0
Autor:
J N, Bidard, L, Cronenberger
Publikováno v:
Journal of chromatography. 164(2)
4-O-Methyldopamine was identified and assayed in tissues from L-dopa treated rats by reversed-phase high-performance liquid chromatography. The initial steps in the separation of catecholamines were performed by alumine, a weak cation-exchange resin,
Publikováno v:
Archives internationales de physiologie et de biochimie. 86(4)
The repartition of [3H]L-dopa administered i.p. does not change in rats treated with S-adenosyl-L-methionine (SAM). The effect was studied on the central nervous system and at the periphery. The biosynthesis of metabolites [3H]dopamine and [3H]3-O-me
Publikováno v:
The Journal of biological chemistry. 259(13)
Purified ciguatoxin at 0.1 to 10 ng/ml inhibits the net accumulation of neurotransmitters (gamma-aminobutyric acid and dopamine) by brain synaptosomes. This action is due to a stimulation of neurotransmitter release. The half-maximum effect of the to