Zobrazeno 1 - 10 of 14 pro vyhledávání: '"J.-M. Vicat"'
1
Bacterial DNA Methylation and Gene Transfer Efficiency
Autor: M. Laine, J.-M. Vicat, S. Allamane, David Ratel, Didier Wion, Isabelle Dupré, A.L. Benabid, P. Jourdes, François Berger
Publikováno v: Biochemical and Biophysical Research Communications. 276:1261-1264
The necessary amplification step in bacteria of any plasmid currently used in DNA immunization or gene therapy introduces modification in the nucleotide sequence of plasmid DNA used in gene transfer. These changes affect the adenine and the internal
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29b28a7254e3b0e2d4cc56c364465dc2
https://doi.org/10.1006/bbrc.2000.3603
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2
Brief Report: Muscle Transfection by Electroporation with High-Voltage and Short-Pulse Currents Provides High-Level and Long-Lasting Gene Expression
Autor: S. Boisseau, J.-M. Vicat, Rabia Bouali-Benazzouz, François Berger, Didier Wion, Alim-Louis Benabid, M. Laine, P. Jourdes
Publikováno v: Human Gene Therapy. 11:909-916
Gene transfer into muscle by electroporation with low-voltage and long-pulse (LV/LP, 100 V/50 msec) currents was shown to be more efficient than simple intramuscular DNA injection. Nevertheless, transgene expression declined from day 7 and only reach
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ad49528e758f9831f341a3dd8bcaff5
https://doi.org/10.1089/10430340050015518
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3
Therapeutic efficacy of the thymidine kinase/ganciclovir system on large experimental gliomas: a nuclear magnetic resonance imaging study
Autor: S. Boisseau, Rabia Bouali-Benazzouz, François Berger, N Fouilhé, Chantal Rémy, Marie-France Nissou, M. Laine, J.-M. Vicat, A.L. Benabid, F Thomas
Publikováno v: Gene Therapy. 6:1030-1037
Contradictory experimental results and human trials have questioned the clinical relevance of the HSVtk/ganciclovir system. To bypass the problem of transfection efficiency, we used a glioma cell line stably expressing the HSVtk gene, which was also
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f726c46e401a1fc39e9f587431dfa914
https://doi.org/10.1038/sj.gt.3300921
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4
Mycoplasma: a new potential vector for gene therapy?
Autor: Didier Wion, A.L. Benabid, François Berger, J.-M. Vicat, Cécile Canova
Publikováno v: Medical hypotheses. 52(6)
The introduction of foreign genetic material in living cells is the basis of the current protocols of gene therapy. The concept that the de novo synthesis of a foreign therapeutic protein requires the entrance of the corresponding gene into target ce
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f860dc76c6db6b2104541b103dc70251
https://pubmed.ncbi.nlm.nih.gov/10459845
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5
Increased bax expression is associated with cell death induced by ganciclovir in a herpes thymidine kinase gene-expressing glioma cell line
Autor: Alim-Louis Benabid, M.-F. Nissou, D. Craperi, J.-M. Verna, Jacques Baudier, J.-M. Vicat, J. Mathieu
Publikováno v: Human gene therapy. 10(4)
The herpes simplex virus thymidine kinase gene (HSV-tk) was stably transfected into rat C6 glioma cells (C6tk) in order to characterize the mechanisms underlying cell toxicity induced in vitro by the guanosine analog ganciclovir (GCV). The results de
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d7579344bcb2c9e95105d18de370454
https://pubmed.ncbi.nlm.nih.gov/10094211
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9
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10
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