Parallel synthesis and pharmacological screening of nonpeptide ligands of the neuropeptide Y receptor subtype Y5

Autor: J M, Henlin, J A, Boutin, F, Duchêne-Roger, J P, Nicolas, C, Desmet-Beaufort, N, Levens, J L, Fauchère

Publikováno v: The journal of peptide research : official journal of the American Peptide Society. 57(5)

Several series of low-molecular-mass ligands of the neuropeptide receptor subtype Y5 were prepared using a mixed strategy of synthesis on solid phase and in solution. Collections of single compounds were obtained by an automated parallel procedure wh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::60fef4d547bbc5c7e154b7974c1469ed
https://pubmed.ncbi.nlm.nih.gov/11350602

Peptide and nonpeptide lead discovery using robotically synthesized soluble libraries

Autor: J L, Fauchère, J M, Henlin, J A, Boutin

Publikováno v: Canadian journal of physiology and pharmacology. 75(6)

The method of combinatorial synthesis of peptide and nonpeptide libraries on solid phase is analyzed and the automation of the mix and divide key step described. A set of amino acids leading to a high molecular diversity is proposed as well as a numb

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::417dab3005de6d707ff8ddf9b9ec42a5
https://pubmed.ncbi.nlm.nih.gov/9276149

ChemInform Abstract: Stereospecific Synthesis of 2-Oxazinyl-4-oxoazetidinecarbamates Starting from a 1,2-Diazepine. A New Type of Intramolecular Transbenzoylation

Autor: Hans Fritz, T. Tschamber, J. Streith, J.-M. Henlin, Andreas Riesen, Margareta Zehnder

Publikováno v: ChemInform. 19

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::00f31dbc5472fcdff6df1b0c73d47cd3
https://doi.org/10.1002/chin.198839211

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Design, Synthesis, and Evaluation of BCL-2 Targeting PROTACs.

Autor: Bricelj A; Faculty of Pharmacy, University of Ljubljana, Aškerčeva cesta 7, SI-1000, Ljubljana, Slovenia., Dora Ng YL; Department of Hematology, Oncology and Cancer Immunology, Charité - Universitätsmedizin Berlin, Hindenburgdamm 30, D-12203, Berlin, Germany., Gobec M; Faculty of Pharmacy, University of Ljubljana, Aškerčeva cesta 7, SI-1000, Ljubljana, Slovenia., Kuchta R; Pharmaceutical Institute, Department of Pharmaceutical & Medicinal Chemistry, University of Bonn, An der Immenburg 4, D-53121, Bonn, Germany., Hu W; Department of Medicinal Chemistry, College of Pharmacy, University of Florida, 32610, Gainesville, FL, USA., Javornik Š; Faculty of Pharmacy, University of Ljubljana, Aškerčeva cesta 7, SI-1000, Ljubljana, Slovenia., Rožič M; Faculty of Pharmacy, University of Ljubljana, Aškerčeva cesta 7, SI-1000, Ljubljana, Slovenia., Gütschow M; Pharmaceutical Institute, Department of Pharmaceutical & Medicinal Chemistry, University of Bonn, An der Immenburg 4, D-53121, Bonn, Germany., Zheng G; Department of Medicinal Chemistry, College of Pharmacy, University of Florida, 32610, Gainesville, FL, USA., Krönke J; Department of Hematology, Oncology and Cancer Immunology, Charité - Universitätsmedizin Berlin, Hindenburgdamm 30, D-12203, Berlin, Germany., Steinebach C; Pharmaceutical Institute, Department of Pharmaceutical & Medicinal Chemistry, University of Bonn, An der Immenburg 4, D-53121, Bonn, Germany., Sosič I; Faculty of Pharmacy, University of Ljubljana, Aškerčeva cesta 7, SI-1000, Ljubljana, Slovenia.

Publikováno v: Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2024 Aug 12; Vol. 30 (45), pp. e202400430. Date of Electronic Publication: 2024 Jul 25.