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pro vyhledávání: '"J.-I. Miyazaki"'
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Publikováno v:
Diabetologia. 39:1293-1298
Various genes are differentially expressed in cells during cell differentiation, development, aging, and in pathological conditions. To identify and isolate the genes that are specifically and differentially expressed in cells, we established a ligat
Publikováno v:
Biochemical and Biophysical Research Communications. 217:393-401
We have constructed an E1-defective adenovirus (Ad) vector designated AdCAG-Cre containing the Cre recombinase gene derived from bacteriophage P1 under control of the cytomegalovirus immediate early enhancer-chicken beta-actin hybrid (CAG) promoter.
Autor:
Hisamitsu Ishihara, Tomoichiro Asano, J.-I. Miyazaki, Katsunori Tsukuda, Yoshitomo Oka, Motonobu Anai, Kouichi Inukai, Masatoshi Kikuchi, Hideki Katagiri, Yoshio Yazaki
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 269:E897-E902
Accumulated evidence suggests that GLUT-2, in addition to its role in glucose transport, may also have other functions in glucose-stimulated insulin secretion. As a first step in addressing this possibility, we have engineered MIN6 cells overexpressi
Autor:
J.-I. Miyazaki, Hisamitsu Ishihara, Motonobu Anai, Hideki Katagiri, Kouichi Inukai, Yasushi Fukushima, Tomiyasu Murata, Masatoshi Kikuchi, Yoshitomo Oka, Jungo Terasaki, Yoshio Yazaki, Takehide Ogihara
Publikováno v:
Journal of Biological Chemistry. 270:4963-4966
munc-18/n-Sec1/rbSec1, a brain homologue of the yeast Sec1p protein, is thought to participate in regulating the docking and fusion of synaptic vesicles. We have screened the mouse cDNA library of an MIN6 cell line, derived from pancreatic beta cells
Autor:
Katsunori Tsukuda, Tomoichiro Asano, Hisamitsu Ishihara, Motonobu Anai, Yoshio Yazaki, Masatoshi Kikuchi, J.-I. Miyazaki, Hideki Katagiri, Yoshitomo Oka, Kouichi Inukai
Publikováno v:
Journal of Biological Chemistry. 269:3081-3087
The recently established pancreatic beta-cell line MIN6 retains the ability to secrete insulin in response to physiological glucose concentrations. To investigate the role of glucose transport and phosphorylation in glucose-stimulated insulin secreti
Autor:
Kiyoaki Watanabe, Akira Shimada, Tomohiro Kasatani, Takao Saruta, Sonoko Habu, Taro Maruyama, Izumi Takei, Akira Kasuga, J.-I. Miyazaki, Toshio Nakaki
Publikováno v:
Diabetologia. 36:1252-1257
The cytotoxicity of macrophages from non-obese diabetic (NOD) mice against murine mastocytoma (P-815), and murine beta-cell lines having the NOD gene background (MIN6N-9a), were examined. Peritoneal exudate cells from 20-week-old mice showed higher c
Publikováno v:
Journal of Biological Chemistry. 268:26452-26460
Rat liver mitochondrial fatty acid oxidation multienzyme complex consists of 4 mol of the alpha-subunit and 4 mol of the beta-subunit, and has three enzyme activities of long chain enoyl-CoA hydratase, long chain 3-hydroxyacyl-CoA dehydrogenase, and