Zobrazeno 1 - 10
of 58
pro vyhledávání: '"J.-F. Mayaux"'
Autor:
A. Bousseau, Y. Lelievre, Y. Ribeill, N Dereu, J.-C. Gueguen, Y. Henin, J.-B. Le Pecq, M. Evers, F. Soler, E. De Clercq, D. Reisdorf, I. Morize, J F Mayaux, Rudi Pauwels, C Poujade, C. James
Publikováno v:
Journal of Medicinal Chemistry. 39:1056-1068
A series of omega-undecanoic amides of lup-20(29)-en-28-oic acid derivatives were synthesized and evaluated for activity in CEM 4 and MT-4 cell cultures against human immunodeficiency virus type 1 (HIV-1) strain IIIB/LAI. The potent HIV inhibitors wh
Autor:
A. Bousseau, Y. Lelievre, Y. Henin, M. Evers, J.-B. Le Pecq, C Poujade, C. James, E. De Clercq, J F Mayaux, Rudi Pauwels, I. Morize, D. Reisdorf, Y. Ribeill, F. Soler, N Dereu, J.-C. Gueguen
Publikováno v:
ChemInform. 27
A series of omega-undecanoic amides of lup-20(29)-en-28-oic acid derivatives were synthesized and evaluated for activity in CEM 4 and MT-4 cell cultures against human immunodeficiency virus type 1 (HIV-1) strain IIIB/LAI. The potent HIV inhibitors wh
Autor:
C Poujade, J F Mayaux, T Huet, A. Bousseau, Rudi Pauwels, J.‐C. Carry, N Dereu, F. Soler, Y. Henin, J.-B. Le Pecq, M. Evers, E. De Clercq
Publikováno v:
ChemInform. 27
A novel series of omega-aminoalkanoic acid derivatives of betulinic acid were synthesized and evaluated for their activity against human immunodeficiency virus (HIV). The anti-HIV-1 activity of several members of this new series was found to be in th
Autor:
B. Cambou, Yves Lelièvre, C. Giuliacci, Terence Cartwright, G. Jung, A. Dugué, Fabienne Parker, J. Boiziau, J.-F. Mayaux, Ph.-H. Hirel, D. Outerovitch, C. Peltiers, R. Boulay
Publikováno v:
Antiviral Chemistry and Chemotherapy. 1:9-15
The 99-amino-acid HIV-1 aspartic proteinase was expressed to high levels in Escherichia coli using a T7 expression system. About 50% of the insoluble material after sonication of the bacteria was composed of aggregated proteinase. Subsequent renatura
Autor:
Rudi Pauwels, A. Bousseau, Y. Henin, J.-B. Le Pecq, M. Evers, C Poujade, E. De Clercq, F. Soler, T Huet, J F Mayaux, J.‐C. Carry, N Dereu
Publikováno v:
Journal of medicinal chemistry. 39(5)
A novel series of omega-aminoalkanoic acid derivatives of betulinic acid were synthesized and evaluated for their activity against human immunodeficiency virus (HIV). The anti-HIV-1 activity of several members of this new series was found to be in th
Autor:
L, Pradier, J, Ménager, J, Le Guern, M D, Bock, E, Heuillet, V, Fardin, C, Garret, A, Doble, J F, Mayaux
Publikováno v:
Molecular pharmacology. 45(2)
The hexapeptide [pGlu6,Pro9]substance P (SP)6-11, septide, has been shown to be an agonist as potent as SP in eliciting smooth muscle contraction in several in vitro preparations, while being a poor competitor of labeled SP binding. These results, as
Autor:
Jan Haavik, P Denèfle, Philippe Horellou, B. Le Bourdellès, Bernard Guibert, J.P. Le Caer, J F Mayaux, Jacques Mallet, M Latta
Publikováno v:
Scopus-Elsevier
Europe PubMed Central
Europe PubMed Central
The single human tyrosine hydroxylase (TH) gene generates four different mRNA species through alternative splicing events. TH-1 and TH-2 mRNAs are expressed mostly in the brain. We have produced large amounts of the corresponding proteins in Escheric
Publikováno v:
Advances in second messenger and phosphoprotein research. 24
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Publikováno v:
Annales de l'Institut Pasteur. Microbiology. 139(1)
A high-productivity process has been developed for the production of mature human interleukin-1 beta (IL-1 beta) from recombinant Escherichia coli strains. Conditions were found that allow high IL-1 beta expression levels in high cell density culture