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pro vyhledávání: '"J.-F. Dubremetz"'
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Autor:
Marie Knockaert, Laurent Meijer, Karen M. Grant, David Fergusson, M. Soete, Eve Damiens, K. Le Roch, Nathanael S. Gray, Jeremy C. Mottram, Peter G. Schultz, Christian Doerig, Young-Tae Chang, J.-F. Dubremetz, Philippe Grellier
Publikováno v:
ResearcherID
BACKGROUND: Chemical inhibitors of cyclin-dependent kinases (CDKs) have great therapeutic potential against various proliferative and neurodegenerative disorders. Olomoucine, a 2,6,9-trisubstituted purine, has been optimized for activity against CDK1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fd652077da15e7e8cbdb2b056526af9
https://doi.org/10.1016/s1074-5521(00)00124-1
https://doi.org/10.1016/s1074-5521(00)00124-1
Publikováno v:
Journal of Biological Chemistry. 267:21446-21458
Toxoplasmosis, a disease that affects humans and a wide variety of mammals is caused by Toxoplasma gondii, the obligate intracellular coccidian protozoan parasite. Most T. gondii research has focused on the rapidly growing invasive form, the tachyzoi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::381e3ec87c7a9484bff3699630211678
https://doi.org/10.1016/s0021-9258(19)36630-x
https://doi.org/10.1016/s0021-9258(19)36630-x
Publikováno v:
Journal of Biological Chemistry. 267:11721-11728
Four major glycolipids were extracted from Toxoplasma gondii tachyzoites which were metabolically labeled with tritiated glucosamine, mannose, palmitic and myristic acid, ethanolamine, and inositol. Judging from their sensitivity to a set of enzymati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d0e8d27446c281a1817a4d9fb1d797f5
https://doi.org/10.1016/s0021-9258(19)49757-3
https://doi.org/10.1016/s0021-9258(19)49757-3
Publikováno v:
Annales pharmaceutiques francaises. 59(5)
Protozoan of the phylum Apicomplexa are of high medical and veterinary importance, causing diseases such as malaria, toxoplasmosis and cryptosporidiosis. Invasive stages of apicomplexans possess organelles named micronemes, which are involved in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fb9ce471cea240c4c9d3511cef09f472
https://pubmed.ncbi.nlm.nih.gov/11787421
https://pubmed.ncbi.nlm.nih.gov/11787421
Autor:
J.D. Schwartzman, J.-F. Dubremetz
Publikováno v:
Research in Immunology. 144:31-33
Identification of candidate glycolipid precursor(s) for Toxoplasma gondii glycosylphosphatidylinositol membrane anchors. J. biol. Chem., 267,11721-l 1728. Tomavo, S., Dubremetz, J.-F. & Schwarz, R.T. (1992b). Cell-free synthesis of glycolipid candida
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d73a8b149915160f9c8be6fc7b879b2
https://doi.org/10.1016/s0923-2494(05)80093-8
https://doi.org/10.1016/s0923-2494(05)80093-8
Autor:
S, Girault, T E, Davioud-Charvet, L, Maes, J F, Dubremetz, M A, Debreu, V, Landry, C, Sergheraert
Publikováno v:
Bioorganicmedicinal chemistry. 9(4)
In order to optimise the activity of bis(2-aminodiphenylsulfides) upon trypanothione reductase (TR) from Trypanosoma cruzi, a new series of bis(2-aminodiphenylsulfides) possessing three side chains was synthesized. Various moieties were introduced at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4e6d4dfcbe099c88e52455f1a072de90
https://pubmed.ncbi.nlm.nih.gov/11354666
https://pubmed.ncbi.nlm.nih.gov/11354666
Autor:
Yves Carlier, T. Scorza, A el Bouhdidi, M. Vercammen, Hendrik Verschueren, K Van Beeck, J.-F. Dubremetz
We have recently shown that Toxoplasma gondii tachyzoites grown in in vitro culture can bind unspecific immunoglobulin (Ig) through their Fc moiety. We show now that Fc receptors are also present on T. gondii within the host animal, and that intraper
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f03f0217161ab27688e6e0a0d44e5037
https://hdl.handle.net/20.500.14017/7a3a8584-519a-4339-8d89-2c2e0ab014f6
https://hdl.handle.net/20.500.14017/7a3a8584-519a-4339-8d89-2c2e0ab014f6
Publikováno v:
The Journal of parasitology. 85(3)
Hammondia hammondi and Toxoplasma gondii, 2 closely related coccidia of cats, are known to share many antigenic molecules as shown by serologic cross reactivity. Monoclonal antibodies (MAbs) directed against the internal organelles of Toxoplasma gond
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::573f96e5da7b95ca99cb2487a2ea4182
https://pubmed.ncbi.nlm.nih.gov/10386461
https://pubmed.ncbi.nlm.nih.gov/10386461
Publikováno v:
Antimicrobial agents and chemotherapy. 43(6)
We investigated the effect of protease inhibitors on the asexual development of the protozoan parasite Toxoplasma gondii . Among the inhibitors tested only two irreversible serine protease inhibitors, 3,4-dichloroisocoumarin and 4-(2-aminoethyl)-benz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0426eba0961429be28896cc864a99aaa
https://pubmed.ncbi.nlm.nih.gov/10348752
https://pubmed.ncbi.nlm.nih.gov/10348752