Zobrazeno 1 - 10
of 145
pro vyhledávání: '"J.-D. Horisberger"'
Autor:
J. D. Horisberger
Publikováno v:
American Journal of Physiology-Cell Physiology. 263:C384-C388
The early effects (1-4 h) of aldosterone on membrane conductance were studied in the TBM cells, an epithelial cell line derived from the toad urinary bladder. Aldosterone stimulated Na+ transport (measured as short-circuit current) and induced parall
Autor:
Bernard C. Rossier, J D Horisberger
Publikováno v:
Hypertension. 19:221-227
Aldosterone, like other steroid hormones, initiates its effects by binding to intracellular receptors; these receptors are then able to control the transcription of several genes. The products of these genes eventually modulate the activity of ionic
Autor:
J.-D. Horisberger, K. Geering
The distribution of Na,K-ATPase isoforms in the nervous system is rather complex, but it can be roughly summarized as follows: α1 isoform is ubiquitous, α2 isoform is mostly expressed in astrocytes, and α3 isoform is generally restricted to neuron
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e98dd2f397a83093da783d96b50860d7
https://doi.org/10.1016/b978-008045046-9.01737-x
https://doi.org/10.1016/b978-008045046-9.01737-x
Autor:
J. D. Horisberger
Publikováno v:
American Journal of Physiology-Cell Physiology. 260:C1172-C1181
Cultured cell lines present several advantages over whole organ or ex vivo isolated epithelium for the physiological and biochemical study of epithelial transport. We have developed a new technique allowing for simultaneous intracellular and transepi
Publikováno v:
Lab on a chip. 8(11)
We present a new lab-on-a-chip system for electrophysiological measurements on Xenopus oocytes. Xenopus oocytes are widely used host cells in the field of pharmacological studies and drug development. We developed a novel non-invasive technique using
Publikováno v:
Biosensorsbioelectronics. 22(12)
We developed a new non-invasive integrated microsystem for electrophysiological measurements on Xenopus laevis oocytes. The Xenopus oocyte is a well-known expression system for various kinds of ion channels that are of potential interest for drug scr
Autor:
J.-D. Horisberger
Publikováno v:
Physiology (Bethesda, Md.). 19
The sodium pump (or Na-K-ATPase) is essential to the function of animal cells. Publication of the related calcium pump (SERCA) structure together with several recent results from a variety of approaches allow us to propose a mechanistic model to answ
Publikováno v:
Biosensorsbioelectronics. 16(9-12)
We have realised a microsystem for the culture and electrical characterisation of epithelial cell layers for cell-based diagnostic applications. The main goal of this work is to achieve both cell culture and impedimetric and potentiometric characteri
Autor:
J D, Horisberger
Publikováno v:
The New England journal of medicine. 342(5)
Autor:
E, Hummler, J D, Horisberger
Publikováno v:
The American journal of physiology. 276(3)
The epithelial Na+ channel (ENaC) controls the rate-limiting step in the process of transepithelial Na+ reabsorption in the distal nephron, the distal colon, and the airways. Hereditary salt-losing syndromes have been ascribed to loss of function mut