Zobrazeno 1 - 10
of 162
pro vyhledávání: '"J.-C. Mani"'
Autor:
Elizabeth Fischer, S Lecoanet-Henchoz, J C Mani, J.Y. Bonnefoy, Véronique Frémeaux-Bacchi, Michel D. Kazatchkine
Publikováno v:
International Immunology. 10:1459-1466
A soluble form of CD21 (sCD21) of 135 kDa is spontaneously released by human B and T lymphocytes upon shedding of the extracellular domain of the molecule. By Western blotting, we have now identified two forms of sCD21 of Mr 135 and 90 kDa in normal
Autor:
G Badouaille, Xavier Jeunemaitre, Thanh Tam Guyene, Anne-Paule Gimenez-Roqueplo, Joël Ménard, J.-C. Mani, Bernard Pau, P. Cohen, D Simon, Pierre Corvol
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 81:3505-3512
The common M235T mutation of human angiotensinogen has been shown to be associated with a 10-20% increase in plasma angiotensinOgen level and increased frequency of essential and pregnancy-induced hypertension. The detection of such a common factor i
Publikováno v:
Journal of Biological Chemistry. 269:29435-29443
We have used a monoclonal antibody-based binding procedure to determine the dissociation constants of the interactions between the essential antithrombin-binding pentasaccharide and a series of 13 distinct N- and C-terminal antithrombin substitution
Autor:
Martine Piechaczyk, Djoko Wahyono, C Girard, J M Scherrmann, J Grenier, Jean-Marie Bastide, B. Pau, J C Mani
Publikováno v:
Therapeutic Drug Monitoring. 13:113-119
Four digoxin radioimmunoassays (RIA) were evaluated using four antidigoxin monoclonal antibodies (MAb) with different binding specificities for digoxin metabolites and other glycosides. These RIA have been used to measure the apparent digoxin concent
Publikováno v:
Clinical science (London, England : 1979). 98(4)
beta(2)-Microglobulin, a 12 kDa protein forming part of the class I HLA (histocompatibility locus antigen) major histocompatibility complex, has been used as a prognosis factor for multiple myeloma and as a marker of renal function, and has been show
Publikováno v:
The Journal of biological chemistry. 275(3)
Thyroglobulin (TG) is secreted by the thyrocytes into the follicular lumen of the thyroid. After maturation and hormone formation, TG is endocytosed and delivered to lysosomes. Quality control mechanisms may occur during this bidirectional traffic si
Publikováno v:
Blood. 93(12)
It is widely accepted that the serum of healthy individuals contains natural antibodies only against those blood group A or B antigens that are not expressed on the individual's red blood cells. The mechanisms involved in tolerance to autologous bloo
Autor:
T L, Vassilev, M D, Kazatchkine, J P, Duong Van Huyen, M, Mekrache, E, Bonnin, J C, Mani, C, Lecroubier, D, Korinth, D, Baruch, F, Schriever, S V, Kaveri
Publikováno v:
Blood. 93(11)
Intravenous immunoglobulin (IVIg) therapy is associated with a broad range of immunomodulatory activities. Several of the postulated mechanisms of IVIg action relate to the presence of antibodies to molecules relevant for regulation of the immune res
Publikováno v:
European cytokine network. 10(1)
Interleukin-6 (IL-6) is used as a growth factor by various tumor cells. It binds to a gp80 specific receptor (IL-6R) and then to a gp130 transducing chain. Both receptor chains are released as soluble functional proteins which circulate in biological
Publikováno v:
International journal of cancer. 80(6)
The mannose-6-phosphate/insulin-like growth-factor-II receptor (M6P/IGFII-R) involved in trafficking of newly synthesized lysosomal enzymes, degradation of IGFII and activation of TGFbetaI, was suggested as being coded by a tumor-suppressor gene. No