Zobrazeno 1 - 10
of 94
pro vyhledávání: '"J.-C. Levron"'
Autor:
Benoit Vallet, J. C. Levron, P. Scherpereel, Jean-Frederic Colombel, Pierre Desreumaux, M. Fleyfel, Luc Gambiez, A. Guidat
Publikováno v:
European Journal of Anaesthesiology. 20:957-962
BACKGROUND AND OBJECTIVE Inflammation promotes hyperalgesia and increases opioid binding protein (alpha1-acid glycoprotein) inducing increased opioid requirement. To investigate the influence of an acute episode of inflammatory bowel disease in opioi
Autor:
Patrice Assoune, Laurent Jacob, Jean-Pierre Le Moing, S Boudaoud, B Eurin, Christian Troje, Isabelle Leblanc, J.-C. Levron, Frédéric Ethuin, O. Marie
Publikováno v:
Intensive Care Medicine. 29:1916-1920
To determine the pharmacokinetics of long-term infusion of sufentanil in ICU patients. Open-label study in a surgical intensive care unit. Ten consecutive patients without renal or hepatic failure requiring mechanical ventilation for at least 6 days.
Publikováno v:
Journal of Clinical Anesthesia. 14:578-583
Study objective To test our hypothesis that sequestration of sufentanil can occur during surgery when a pneumatic tourniquet is used. Design Prospective, randomized study. Setting Operating room and recovery room of a university hospital. Patients 16
Publikováno v:
Anaesthesia. 55:1202-1207
The pharmacokinetics of transdermal fentanyl were assessed in eight children aged 18-60 months, weighing 11-20 kg and monitored postoperatively in the intensive care unit. A patch, delivering 25 microg.h-1 of fentanyl, was applied for 72 h from the i
Autor:
Florence Persat, N. Kranzhöfer, A Belhabri, C. Prat, Mauricette Michallet, J.-C. Levron, Marie-Antoinette Piens, J. P. Le Moing, Denis Fiere, E. Chwetzoff
Publikováno v:
Bone Marrow Transplantation. 21:1239-1243
A prospective study of the pharmacokinetics of itraconazole solution was performed in 11 patients who underwent allogeneic BMT (day of BMT = day 0) after a conditioning regimen including total body irradiation (TBI). Itraconazole solution (400 mg onc
Autor:
J.-C. Levron, Dominique Grimaud, M. Kaidomar, Bernard Goubaux, Marc Raucoules-Aimé, J. Gugenheim, J.-P. Le Moing
Publikováno v:
Anesthesia & Analgesia. 84:1019-1024
Alfentanil and sufentanil are used in the anesthetic management of patients undergoing orthotopic liver transplantation (OLT) and are extensively metabolized by the liver. We examined the influence of OLT on the removal of these opioids. 14 patients
Publikováno v:
Mycoses. 43:125-127
Itraconazole distribution is largely dependent on its high liposolubility. Intrapulmonary lung concentrations remain unknown in haematological patients. We report itraconazole lung concentrations in such patients treated with itraconazole. Itraconazo
Autor:
Gregory Slepchenko, Nicolas Simon, Jean-Pierre Le Moing, J.-C. Levron, Bernard Goubaux, Marc Raucoules-Aimé
Publikováno v:
Anesthesiology. 98(1)
Background Because obesity might affect pharmacokinetic parameters, the authors evaluated the accuracy of target-controlled sufentanil infusion in morbidly obese patients using a pharmacokinetic model usually applied to a normal-weight population. Me
Autor:
A. Henrot, C. Le Guellec, Elisabeth Autret-Leca, Gilles Paintaud, F. Odoul, E. Saliba, M. C. Saux, J. C. Levron
Publikováno v:
European journal of clinical pharmacology. 58(8)
We conducted a population pharmacokinetic analysis of cisapride in neonates to study whether metabolic immaturity in this population may lead to increased concentrations. Methods. Cisapride was administered orally in 91 neonates at the dose of 0.2 mg
Autor:
G. P. Pageaux, Bruno Lacarelle, O. Blin, P. Bouhours, J. P. Le Moing, M. Barugola Nataf, J.-C. Levron, Joëlle Micallef
Publikováno v:
British journal of clinical pharmacology. 51(2)
Aims The primary objective of this study was to determine how the pharmacokinetics of sabeluzole, an investigational drug with specific effects on memory and learning abilities, are affected by chronic liver disease. Since sabeluzole is metabolised b