Zobrazeno 1 - 10
of 146
pro vyhledávání: '"J.-B. Le Pecq"'
Autor:
J-B. Le Pecq, Bernard-Pierre Roques, A. Jacquemin-Sablon, Ch. Garbay-Jaureguiberry, P. Rigaudy
Publikováno v:
International Journal of Peptide and Protein Research. 30:347-355
In order to specifically direct cytotoxic agents against tumor cells bearing delta opioid receptors, the DNA intercalating agents ellipticine and 9-OH-ellipticine were coupled by quaternarization of the pyridine nitrogen to an enkephalin modified pen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c68ba0738e85564fc629c4982e42b05
https://doi.org/10.1111/j.1399-3011.1987.tb03341.x
https://doi.org/10.1111/j.1399-3011.1987.tb03341.x
Publikováno v:
Annales Pharmaceutiques Françaises. 63:312-328
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9338a1891f40322ca86fd993cf033540
https://doi.org/10.1016/s0003-4509(05)82297-7
https://doi.org/10.1016/s0003-4509(05)82297-7
Autor:
A. Bousseau, Y. Lelievre, Y. Ribeill, N Dereu, J.-C. Gueguen, Y. Henin, J.-B. Le Pecq, M. Evers, F. Soler, E. De Clercq, D. Reisdorf, I. Morize, J F Mayaux, Rudi Pauwels, C Poujade, C. James
Publikováno v:
Journal of Medicinal Chemistry. 39:1056-1068
A series of omega-undecanoic amides of lup-20(29)-en-28-oic acid derivatives were synthesized and evaluated for activity in CEM 4 and MT-4 cell cultures against human immunodeficiency virus type 1 (HIV-1) strain IIIB/LAI. The potent HIV inhibitors wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::050517349681e5f63e2cc58c8e4b47e9
https://doi.org/10.1021/jm950670t
https://doi.org/10.1021/jm950670t
Autor:
Huixiong Chen, Tocque Bruno, Christiane Garbay, J. B. Le Pecq, Bernard-Pierre Roques, Patrick Mailliet, Alain Commercon, Parker Fabienne, J. Boiziau
Publikováno v:
Journal of Medicinal Chemistry. 37:845-859
Potent inhibitors of EGF-dependent protein tyrosine kinase (PTK) activity were synthesized in a series of 5-[(2,5-dihydroxybenzyl)amino]salicylates. Several of these compounds inhibited EGF-dependent DNA synthesis in ER 22 cells with IC50 < 1 microM.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d72c12d4606918763877ab7b21c60dc
https://doi.org/10.1021/jm00032a020
https://doi.org/10.1021/jm00032a020
Autor:
A. Bousseau, Y. Lelievre, Y. Henin, M. Evers, J.-B. Le Pecq, C Poujade, C. James, E. De Clercq, J F Mayaux, Rudi Pauwels, I. Morize, D. Reisdorf, Y. Ribeill, F. Soler, N Dereu, J.-C. Gueguen
Publikováno v:
ChemInform. 27
A series of omega-undecanoic amides of lup-20(29)-en-28-oic acid derivatives were synthesized and evaluated for activity in CEM 4 and MT-4 cell cultures against human immunodeficiency virus type 1 (HIV-1) strain IIIB/LAI. The potent HIV inhibitors wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e32f14723289347d57c559eccdb13ab0
https://doi.org/10.1002/chin.199627201
https://doi.org/10.1002/chin.199627201
Autor:
C Poujade, J F Mayaux, T Huet, A. Bousseau, Rudi Pauwels, J.‐C. Carry, N Dereu, F. Soler, Y. Henin, J.-B. Le Pecq, M. Evers, E. De Clercq
Publikováno v:
ChemInform. 27
A novel series of omega-aminoalkanoic acid derivatives of betulinic acid were synthesized and evaluated for their activity against human immunodeficiency virus (HIV). The anti-HIV-1 activity of several members of this new series was found to be in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::089bbef12d62be11947b0e631916d3fd
https://doi.org/10.1002/chin.199627202
https://doi.org/10.1002/chin.199627202
Autor:
J. B. Le Pecq
Publikováno v:
Methods of Biochemical Analysis, Volume 20
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::581df36612fb313e9a6c479ffaf1fa9d
https://doi.org/10.1002/9780470110393.ch2
https://doi.org/10.1002/9780470110393.ch2
Publikováno v:
Annales pharmaceutiques francaises. 63(5)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::73cdefc28e5406aa716aa3e0bb0dcef4
https://pubmed.ncbi.nlm.nih.gov/16385780
https://pubmed.ncbi.nlm.nih.gov/16385780
Autor:
Rudi Pauwels, A. Bousseau, Y. Henin, J.-B. Le Pecq, M. Evers, C Poujade, E. De Clercq, F. Soler, T Huet, J F Mayaux, J.‐C. Carry, N Dereu
Publikováno v:
Journal of medicinal chemistry. 39(5)
A novel series of omega-aminoalkanoic acid derivatives of betulinic acid were synthesized and evaluated for their activity against human immunodeficiency virus (HIV). The anti-HIV-1 activity of several members of this new series was found to be in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ebf1fd91b6d74939fa8447fe095f402
https://pubmed.ncbi.nlm.nih.gov/8676342
https://pubmed.ncbi.nlm.nih.gov/8676342
Autor:
B, Lambert, J L, Jestin, P, Bréhin, C, Oleykowski, A T, Yeung, P, Mailliet, C, Prétot, J B, Le Pecq, A, Jacquemin-Sablon, J C, Chottard
Publikováno v:
The Journal of biological chemistry. 270(36)
The interactions of the Escherichia coli endonuclease UvrAB proteins with the DNA mono- and diadducts of both the cis-racemic exo-[N-2-amino-N-2-methylamino-2,2,1-bicycloheptane]dichloroplatin um(II) (complex 1) and cisplatin (cis-diamminedichloropla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e259229f8215ca3337ace2e9e48560bb
https://pubmed.ncbi.nlm.nih.gov/7673159
https://pubmed.ncbi.nlm.nih.gov/7673159