Výsledky vyhledávání - "J. van der Ham"

Akademický článek

Ageing of Plasmodium falciparum malaria sporozoites alters their motility, infectivity and reduces immune activation in vitro

Autor: Roos van Schuijlenburg, Samaneh Azargoshasb, Clarize M. de Korne, Jeroen C. Sijtsma, Sascha Bezemer, Alwin J. van der Ham, Els Baalbergen, Fiona Geurten, Laura M. de Bes-Roeleveld, Severine C. Chevalley-Maurel, Matthias N. van Oosterom, Fijs W. B. van Leeuwen, Blandine Franke-Fayard, Meta Roestenberg

Publikováno v: Malaria Journal, Vol 23, Iss 1, Pp 1-14 (2024)

Abstract Background Sporozoites (SPZ), the infective form of Plasmodium falciparum malaria, can be inoculated into the human host skin by Anopheline mosquitoes. These SPZ migrate at approximately 1 µm/s to find a blood vessel and travel to the liver

Externí odkaz: https://doaj.org/article/2581459e4177448180bc03a9a2272c08

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Akademický článek

Barriers and facilitators in the referral pathways to low vision services from the perspective of patients and professionals: a qualitative study

Autor: M. L. Stolwijk, R. M. A. van Nispen, A. J. van der Ham, E. Veenman, G. H. M. B. van Rens

Publikováno v: BMC Health Services Research, Vol 23, Iss 1, Pp 1-14 (2023)

Abstract Background Underutilization of and lack of access to low vision services (LVS) has been reported internationally. The purpose of this study was to identify barriers and facilitators in LVS referral procedures and service delivery from both t

Externí odkaz: https://doaj.org/article/40cacaded02a452f863aaecd577ec6f0

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Akademický článek

Responding to persons in mental health crisis: A cross-country comparative study of professionals’ perspectives on psychiatric ambulance and street triage models

Autor: Isa C. de Jong, Lia A. J. van der Ham, Mitzi M. Waltz

Publikováno v: Journal of Community Safety and Well-Being, Vol 7, Iss Suppl_1 (2022)

People with mental illness can experience mental health crises (MHCs) that manifest in behaviours risky for the affected persons and for others, often resulting in unwanted police encounters and detention. Mobile crisis teams employing the psychiatri

Externí odkaz: https://doaj.org/article/965fe5f90f8d4d59a4da4c525b1ba7f0

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Akademický článek

mTORC1 signaling in antigen-presenting cells of the skin restrains CD8+ T cell priming

Autor: Leonard R. Pelgrom, Thiago A. Patente, Frank Otto, Lonneke V. Nouwen, Arifa Ozir-Fazalalikhan, Alwin J. van der Ham, Hendrik J.P. van der Zande, Graham A. Heieis, Ramon Arens, Bart Everts

Publikováno v: Cell Reports, Vol 40, Iss 1, Pp 111032- (2022)

Summary: How mechanistic target of rapamycin complex 1 (mTORC1), a key regulator of cellular metabolism, affects dendritic cell (DC) metabolism and T cell-priming capacity has primarily been investigated in vitro, but how mTORC1 regulates this in viv

Externí odkaz: https://doaj.org/article/af5a88d5847d42b5978559763a00c5ea

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Akademický článek

Translation and content validity of the Dutch Impact of Vision Impairment questionnaire assessed by Three-Step Test-Interviewing

Autor: T. P. Rausch – Koster, A. J. van der Ham, C. B. Terwee, F. D. Verbraak, G. H. M. B. van Rens, R. M. A. van Nispen

Publikováno v: Journal of Patient-Reported Outcomes, Vol 5, Iss 1, Pp 1-11 (2021)

Abstract Background Patients suffering from exsudative retinal diseases may experience severe central vision loss and this might have impact on their daily activities and quality of life. To measure the disabilities these patients may have, the use o

Externí odkaz: https://doaj.org/article/bbb78c08e2924e7f912d9c3701950468

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Akademický článek

Experiences with traumatic events, consequences and care among people with visual impairment and post-traumatic stress disorder: a qualitative study from The Netherlands

Autor: Ruth M A van Nispen, Hilde P A van der Aa, Ger H M B van Rens, Alida J van der Ham, Peter Verstraten

Publikováno v: BMJ Open, Vol 11, Iss 2 (2021)

Objective Having a visual impairment is known to be associated with an increased vulnerability to (potentially) traumatic events. Little is known about how people with visual impairment experience and process such events. This qualitative study aimed

Externí odkaz: https://doaj.org/article/3f7e7e2b6b95489886cc4df4d1c6cea7

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Akademický článek

DC-SIGN mediated internalisation of glycosylated extracellular vesicles from Schistosoma mansoni increases activation of monocyte-derived dendritic cells

Autor: Marije E. Kuipers, Esther N.M. Nolte-‘t Hoen, Alwin J. van der Ham, Arifa Ozir-Fazalalikhan, D. Linh Nguyen, Clarize M. de Korne, Roman I. Koning, John J. Tomes, Karl F. Hoffmann, Hermelijn H. Smits, Cornelis H. Hokke

Publikováno v: Journal of Extracellular Vesicles, Vol 9, Iss 1 (2020)

Helminths like Schistosoma mansoni release excretory/secretory (E/S) products that modulate host immunity to enable infection. Extracellular vesicles (EVs) are among these E/S products, yet molecular mechanisms and functionality of S. mansoni EV inte

Externí odkaz: https://doaj.org/article/62b6f2375028412695a0b1dd5cc68874

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