Výsledky vyhledávání - "J. van Veldhuizen"

Akademický článek

Comparative genomics reveals a lack of evidence for pigeons as a main source of stx 2f -carrying Escherichia coli causing disease in humans and the common existence of hybrid Shiga toxin-producing and enteropathogenic E. coli pathotypes

Autor: Angela H. A. M. van Hoek, Janieke N. J. van Veldhuizen, Ingrid Friesema, Claudia Coipan, John W. A. Rossen, Indra L. Bergval, Eelco Franz

Publikováno v: BMC Genomics, Vol 20, Iss 1, Pp 1-14 (2019)

Abstract Background Wild birds, in particular pigeons are considered a natural reservoir for stx 2f-carrying E. coli. An extensive comparison of isolates from pigeons and humans from the same region is lacking, which hampers justifiable conclusions o

Externí odkaz: https://doaj.org/article/0d0cbf05e9884accac2d0f348d34abf7

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Akademický článek

Patient-reported outcomes for patients with metastatic castration-resistant prostate cancer receiving docetaxel and Atrasentan versus docetaxel and placebo in a randomized phase III clinical trial (SWOG S0421)

Publikováno v: Journal of Patient-Reported Outcomes, Vol 2, Iss 1, Pp 1-10 (2018)

Abstract Background SWOG S0421 was a large randomized trial comparing docetaxel/prednisone plus placebo (DPP) to docetaxel/prednisone plus atrasentan over 12 cycles for patients with metastatic castration-resistant prostate cancer (mCRPC). The curren

Externí odkaz: https://doaj.org/article/b886bdc66c744576bec9567dfc8ec7ee

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Data from A Second-Generation 2-Methoxyestradiol Prodrug Is Effective against Barrett's Adenocarcinoma in a Mouse Xenograft Model

Autor: Sushanta K. Banerjee, Peter J. Van Veldhuizen, Emma Borrego-Diaz, Douglas Burns, Saheli Jha, Snigdha Banerjee, Amlan Das, Inamul Haque, Mehmet Tanol, Roger A. Rajewski, Suman Kambhampati

2-Methoxyestradiol (2-ME2) is an endogenous metabolite of estradiol. In preclinical models, 2-ME2 is effective against different types of tumors. Unfortunately, only low systemic concentrations of 2-ME2 can be achieved following oral administration,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54b59b8ee75a277902dad405b0ca682a
https://doi.org/10.1158/1535-7163.c.6535956

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DNA Methyltransferase 1 Targeting Using Guadecitabine Inhibits Prostate Cancer Growth by an Apoptosis-Independent Pathway

Autor: Dev Karan, Manohar Singh, Seema Dubey, Peter J. Van Veldhuizen, Yogen Saunthararajah

Publikováno v: Cancers; Volume 15; Issue 10; Pages: 2763

Epigenetic alterations such as DNA methylation and histone modifications are implicated in repressing several tumor suppressor genes in prostate cancer progression. In this study, we determined the anti-prostate cancer effect of a small molecule drug

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea77050818bcbf1a00b64f239b5347bc
https://doi.org/10.3390/cancers15102763

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Management of Metastatic Clear Cell Renal Cell Carcinoma: ASCO Guideline

Autor: W. Kimryn Rathmell, R. Bryan Rumble, Peter J. Van Veldhuizen, Hikmat Al-Ahmadie, Hamid Emamekhoo, Ralph J. Hauke, Alexander V. Louie, Matthew I. Milowsky, Ana M. Molina, Tracy L. Rose, Shankar Siva, Nicholas G. Zaorsky, Tian Zhang, Rubina Qamar, Terry M. Kungel, Bryan Lewis, Eric A. Singer

Publikováno v: Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 40(25)

PURPOSE To provide recommendations for the management of patients with metastatic clear cell renal cell carcinoma (ccRCC). METHODS An Expert Panel conducted a systematic literature review to obtain evidence to guide treatment recommendations. RESULTS

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::377c2d052c8e7fcc051a767334c6d527
https://pubmed.ncbi.nlm.nih.gov/35728020

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