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Effect of Raloxifene on Bone Mineral Density in Premenopausal Women at Increased Risk of Breast Cancer

Autor: David Venzon, Edison T. Liu, Jennifer Eng-Wong, Carson C. Chow, James C. Reynolds, D. Danforth, J. Zujewski, S. Gantz, David J. Liewehr

Publikováno v: The Journal of Clinical Endocrinology & Metabolism. 91:3941-3946

Context: Raloxifene is a promising breast cancer prevention agent in postmenopausal women at increased risk for breast cancer. The effects of raloxifene in premenopausal women are unknown. Objective: We evaluated the effect of raloxifene in premenopa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e737adb51dc59f2112a99abadd27582
https://doi.org/10.1210/jc.2005-2827

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Effect of tamoxifen on mammographic density

Autor: C K, Chow, D, Venzon, E C, Jones, A, Premkumar, J, O'Shaughnessy, J, Zujewski

Publikováno v: Cancer epidemiology, biomarkersprevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 9(9)

There are strong data showing that increased breast cancer risk is associated with increased mammographic density. Tamoxifen has been shown to decrease the risk of invasive breast cancer and decrease breast density. We sought to demonstrate and calcu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::05a20b287c2e4fd293124f715c3259fa
https://pubmed.ncbi.nlm.nih.gov/11008909

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Engraftment of MDR1 and NeoR gene-transduced hematopoietic cells after breast cancer chemotherapy

Autor: J A, Moscow, H, Huang, C, Carter, K, Hines, J, Zujewski, G, Cusack, C, Chow, D, Venzon, B, Sorrentino, Y, Chiang, B, Goldspiel, S, Leitman, E J, Read, A, Abati, M M, Gottesman, I, Pastan, S, Sellers, C, Dunbar, K H, Cowan

Publikováno v: Blood. 94(1)

To determine whether the multidrug resistance gene MDR1 could act as a selectable marker in human subjects, we studied engraftment of peripheral blood progenitor cells (PBPCs) transduced with either MDR1 or the bacterial NeoR gene in six breast cance

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7f335ce380cb77e496fdda28440c0d3b
https://pubmed.ncbi.nlm.nih.gov/10381498

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Constraints on CD4 recovery postchemotherapy in adults: thymic insufficiency and apoptotic decline of expanded peripheral CD4 cells

Autor: F T, Hakim, R, Cepeda, S, Kaimei, C L, Mackall, N, McAtee, J, Zujewski, K, Cowan, R E, Gress

Publikováno v: Blood. 90(9)

To examine the mechanisms of CD4 reconstitution in an adult population, lymphocyte repopulation was assessed following dose-intense chemotherapy in 25 breast cancer patients, ages 33 to 69 years. Chemotherapy resulted in a greater than 60% reduction

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d416539cc47515bf587d9c6b6cfe6f5d
https://pubmed.ncbi.nlm.nih.gov/9345067

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A phase I study of topotecan followed sequentially by doxorubicin in patients with advanced malignancies

Autor: A W, Tolcher, J A, O'Shaughnessy, R B, Weiss, J, Zujewski, R C, Myhand, E, Schneider, F, Hakim, R, Gress, B, Goldspiel, M H, Noone, L R, Brewster, M R, Gossard, K H, Cowan

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research. 3(5)

Inhibitors of topoisomerase I and topoisomerase II have demonstrated synergy when administered sequentially in several tumor models while having a diminished antitumor effect when given concurrently. To explore the potential for clinical sequence-dep

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::488bd6300dafc479b0e407fc8b217857
https://pubmed.ncbi.nlm.nih.gov/9815746

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