Zobrazeno 1 - 10
of 305
pro vyhledávání: '"J. Zeiss"'
Autor:
Sarah Mullin, Robert McDougal, Kei-Hoi Cheung, Halil Kilicoglu, Amanda Beck, Caroline J. Zeiss
Publikováno v:
Journal of Biomedical Semantics, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Background Identifying chemical mentions within the Alzheimer’s and dementia literature can provide a powerful tool to further therapeutic research. Leveraging the Chemical Entities of Biological Interest (ChEBI) ontology, which is rich in
Externí odkaz:
https://doaj.org/article/4d5adcffd66645abadab243267fd3734
Autor:
Caterina Di Pietro, Ann M. Haberman, Brett D. Lindenbach, Peter C. Smith, Emanuela M. Bruscia, Heather G. Allore, Brent Vander Wyk, Antariksh Tyagi, Caroline J. Zeiss
Publikováno v:
Viruses, Vol 16, Iss 2, p 246 (2024)
Seasonal infection rates of individual viruses are influenced by synergistic or inhibitory interactions between coincident viruses. Endemic patterns of SARS-CoV-2 and influenza infection overlap seasonally in the Northern hemisphere and may be simila
Externí odkaz:
https://doaj.org/article/bf355639ca91449e9e786653ccf5d386
Autor:
Caroline J. Zeiss, Daniel M. Gatti, Olga Toro-Salazar, Crystal Davis, Cathleen M. Lutz, Francis Spinale, Timothy Stearns, Milena B. Furtado, Gary A. Churchill
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 9, Iss 8, Pp 2637-2646 (2019)
Anthracyclines cause progressive cardiotoxicity whose ultimate severity is individual to the patient. Genetic determinants contributing to this variation are difficult to study using current mouse models. Our objective was to determine whether a spec
Externí odkaz:
https://doaj.org/article/fabbdfebe0ba4b8d96fa418a6dcfb938
Publikováno v:
PLoS ONE, Vol 16, Iss 11, p e0260038 (2021)
At present, global immunity to SARS-CoV-2 resides within a heterogeneous combination of susceptible, naturally infected and vaccinated individuals. The extent to which viral shedding and transmission occurs on re-exposure to SARS-CoV-2 is an importan
Externí odkaz:
https://doaj.org/article/825d0863d60046b7aa8b0717fd9673c7
Autor:
Thomas C. Rindflesch, Catherine L. Blake, Michael J. Cairelli, Marcelo Fiszman, Caroline J. Zeiss, Halil Kilicoglu
Publikováno v:
Journal of Biomedical Semantics, Vol 9, Iss 1, Pp 1-14 (2018)
Abstract Background Structured electronic health records are a rich resource for identifying novel correlations, such as co-morbidities and adverse drug reactions. For drug development and better understanding of biomedical phenomena, such correlatio
Externí odkaz:
https://doaj.org/article/3c109e83d23f49d5b864ec0908d7c91b
Autor:
Olga H. Toro-Salazar, Ji Hyun Lee, Kia N. Zellars, Paige E. Perreault, Kathryn C. Mason, Zhu Wang, Kan N. Hor, Eileen Gillan, Caroline J. Zeiss, Daniel M. Gatti, Brooke T. Davey, Shelby Kutty, Bruce T. Liang, Francis G. Spinale
Publikováno v:
Cardio-Oncology, Vol 4, Iss 1, Pp 1-11 (2018)
Abstract Background Anthracycline induced cardiomyopathy is a major cause of mortality and morbidity among pediatric cancer survivors. It has been postulated that oxidative stress induction and inflammation may play a role in the pathogenesis of this
Externí odkaz:
https://doaj.org/article/81eee6c0ac974fc38f9cb55f49d53ef9
Autor:
Emily L. Goldberg, Jennifer L. Asher, Ryan D. Molony, Albert C. Shaw, Caroline J. Zeiss, Chao Wang, Ludmilla A. Morozova-Roche, Raimund I. Herzog, Akiko Iwasaki, Vishwa Deep Dixit
Publikováno v:
Cell Reports, Vol 18, Iss 9, Pp 2077-2087 (2017)
Summary: Aging and lipotoxicity are two major risk factors for gout that are linked by the activation of the NLRP3 inflammasome. Neutrophil-mediated production of interleukin-1β (IL-1β) drives gouty flares that cause joint destruction, intense pain
Externí odkaz:
https://doaj.org/article/ba5a00dc1cfc44ada190e57c986b318e
Autor:
Suvi Mäkeläinen, Marta Gòdia, Minas Hellsand, Agnese Viluma, Daniela Hahn, Karim Makdoumi, Caroline J Zeiss, Cathryn Mellersh, Sally L Ricketts, Kristina Narfström, Finn Hallböök, Björn Ekesten, Göran Andersson, Tomas F Bergström
Publikováno v:
PLoS Genetics, Vol 15, Iss 3, p e1007873 (2019)
Autosomal recessive retinal degenerative diseases cause visual impairment and blindness in both humans and dogs. Currently, no standard treatment is available, but pioneering gene therapy-based canine models have been instrumental for clinical trials
Externí odkaz:
https://doaj.org/article/440e2dd2ef7541c0a70a7c12f3d6f9ec
Autor:
Caroline J Zeiss, Dongwook Shin, Brent Vander Wyk, Amanda P Beck, Natalie Zatz, Charles A Sneiderman, Halil Kilicoglu
Publikováno v:
PLoS ONE, Vol 14, Iss 12, p e0226176 (2019)
Discovery studies in animals constitute a cornerstone of biomedical research, but suffer from lack of generalizability to human populations. We propose that large-scale interrogation of these data could reveal patterns of animal use that could narrow
Externí odkaz:
https://doaj.org/article/9acee538d5c14322a734af1b2c79e878
Autor:
Steven P. Brady, Debora Goedert, Lauren E. Frymus, Francisco Javier Zamora‐Camacho, Peter C. Smith, Caroline J. Zeiss, Mar Comas, Timothy A. Abbott, Silvia P. Basu, Jason C. DeAndressi, Mia E. Forgione, Michael J. Maloney, Joseph L. Priester, Faruk Senturk, Richard V. Szeligowski, Alina S. Tucker, Mason Zhang, Ryan Calsbeek
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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Human activities have caused massive losses of natural populations across the globe. Like many groups, amphibians have experienced substantial declines worldwide, driven by environmental changes such as habitat conversion, pollution, and disease emer