Pushing and pulling proteins into the yeast secretory pathway enhances recombinant protein secretion

Autor: Richard J. Zahrl, Roland Prielhofer, Özge Ata, Kristin Baumann, Diethard Mattanovich, Brigitte Gasser

Publikováno v: Metabolic Engineering. 74:36-48

Yeasts and especially Pichia pastoris (syn Komagataella spp.) are popular microbial expression systems for the production of recombinant proteins. One of the key advantages of yeast host systems is their ability to secrete the recombinant protein int

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3371e87b0fd67b5beb62b30129dfcf1
https://doi.org/10.1016/j.ymben.2022.08.010

Golden Pi CS : a golden gate-derived modular cloning system for applied synthetic biology in the yeast Pichia pastoris

Autor: Hans Marx, Michael Sauer, Richard J. Zahrl, Roland Prielhofer, Brigitte Gasser, Thomas Gassler, Diethard Mattanovich, Stefanie Steuer, Juan J. Barrero, Kristin Baumann

Publikováno v: Recercat. Dipósit de la Recerca de Catalunya
instname
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
BMC Systems Biology
Recercat: Dipósit de la Recerca de Catalunya
Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
BMC Systems Biology, Vol 11, Iss 1, Pp 1-14 (2017)

This work has been supported by the Federal Ministry of Science, Research and Economy (BMWFW), the Federal Ministry of Traffic, Innovation and Technology (bmvit), the Styrian Business Promotion Agency SFG, the Standortagentur Tirol, the Government of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ab9d2244d85b16eb7180ff59f120039
http://hdl.handle.net/2072/427664

Detection and Elimination of Cellular Bottlenecks in Protein-Producing Yeasts

Autor: Brigitte Gasser, Diethard Mattanovich, Richard J. Zahrl, Pau Ferrer

Publikováno v: Methods in Molecular Biology ISBN: 9781493990238

Yeasts are efficient cell factories and are commonly used for the production of recombinant proteins for biopharmaceutical and industrial purposes. For such products high levels of correctly folded proteins are needed, which sometimes requires improv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0dce932c695e7a9a285442cb732e8b9a
https://doi.org/10.1007/978-1-4939-9024-5_2

Systems biotechnology for protein production in Pichia pastoris

Autor: David A. Peña, Diethard Mattanovich, Richard J. Zahrl, Brigitte Gasser

Publikováno v: FEMS Yeast Research. 17

The methylotrophic yeast Pichia pastoris (syn. Komagataella spp.) is one of the most important production systems for heterologous proteins. After the first genome sequences were published in 2009, tremendous effort was made to establish systems-leve

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::372ff5ffd342c7a381d2cc6a2606d232
https://doi.org/10.1093/femsyr/fox068

Rechtliche Grundlagen

Autor: H.-D. Lippert, J. Zahrl, Y. Bollag

Publikováno v: Medizinische Gutachten ISBN: 9783662434246

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7b34b60e065be585554fc043e8dbea47
https://doi.org/10.1007/978-3-662-43425-3_1