Zobrazeno 1 - 10
of 51
pro vyhledávání: '"J. Yuzuru Homma"'
Autor:
J. Yuzuru Homma, Takushi Tadakuma, Tatsuji Yasuda, Toru Tsumita, Masaru Inage, Tetsuo SHlBA, Shiro Kanegasaki, Shoichi Kusumoto
Publikováno v:
European Journal of Biochemistry. 124:405-407
The adjuvant effect of synthetic analogues of lipid A was investigated in tnice in vivo. Two cbf the five synthetic lipid A analogues showed adjuvant activity when they were incorporated into dipalmitoylglyceerophosphocholine-cholesterol-dipalmitoylg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db7f0c269fcd4121285cde5c7b8d32f0
https://doi.org/10.1111/j.1432-1033.1982.tb06607.x
https://doi.org/10.1111/j.1432-1033.1982.tb06607.x
Publikováno v:
Antiviral research. 13(6)
A chemically synthesized lipid A-subunit analogue, GLA-60, 2-deoxy-4-O-phosphono-2-[(3R)-3-hydroxytetradecanamido]-3-O-[(3R)- 3- tetradecanoyloxytetradecanoyl]-D-glucose, has many of the activities of endotoxin but has little toxicity. Then, compound
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d06164ca201b22ed534735088cb7abf6
https://pubmed.ncbi.nlm.nih.gov/1699495
https://pubmed.ncbi.nlm.nih.gov/1699495
Autor:
Mitsunobu Nakatsuka, Chiaki Nishimura, Akira Hasegawa, Yoshio Kumazawa, S. Ikeda, Makoto Kiso, J. Yuzuru Homma, Motohiro Matsuura
Publikováno v:
International journal of immunopharmacology. 12(6)
The C1 position of lipid A-subunit analogue GLA-27, 4-O- phosphono - D - gluxosamine carrying N -3-tetradecanoyloxytetradecanoyl(C 14 - O -(C 14 )) and 3- O -tetradecanoyl (C 14) groups, was S -acetylated, thiolated or phosphorylated. Enhancement of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edf75be1a8d025b6ff0c7ca13bf4d6c3
https://pubmed.ncbi.nlm.nih.gov/1703131
https://pubmed.ncbi.nlm.nih.gov/1703131
Autor:
Yasuda, Tatsuji, Kanegasaki, Shiro, Tsumita, Toru, Tadakuma, Takushi, Ikewaki, Nobunao, J. Yuzuru Homma, Inage, Masaru, Kusumoto, Shoichi, Shiba, Tetsuo
Publikováno v:
European Journal of Biochemistry; 4/16/84, Vol. 140 Issue 2, p245-248, 4p
Autor:
Motohiro Matsuura, Masaru Inage, Nobuyuki Shibukawa, Yasuhiko Kojima, Yoshiyuki Kubota, Masatoshi Shibata, J. Yuzuru Homma, Tetsuo Shiba, Shoichi Kusumoto
Publikováno v:
European Journal of Biochemistry. 137:639-642
Interferon-inducing, pyrogenic and proclotting enzyme of horseshoe crab activation activities of chemically synthesized lipid A analogues were investigated and compared with the same activities of a natural lipid A. These analogues are nonphosphoryla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45db09f68e645e4928a86fb823cb8f10
https://doi.org/10.1111/j.1432-1033.1983.tb07873.x
https://doi.org/10.1111/j.1432-1033.1983.tb07873.x
Publikováno v:
European Journal of Biochemistry. 97:623-629
Resistance against ascites tumor development and interferon-inducing activity were demonstrated in lipopolysaccharide derived from the protein-lipopolysaccharide complex obtained from an autolysate of Pseudomonas aeruginosa. Lipid A obtained from the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c942dd69b6161b7dbf9b59a56cca037
https://doi.org/10.1111/j.1432-1033.1979.tb13152.x
https://doi.org/10.1111/j.1432-1033.1979.tb13152.x
Autor:
Yoshio Kumazawa, Mitsuru Fukumoto, Shoichi Kusumoto, Masaru Inage, Tetsuo Shiba, Chiaki Nishimura, Motohiro Matsuura, Yoko Nakatsuru-Watanabe, J. Yuzuru Homma
Publikováno v:
European Journal of Immunology. 14:109-114
The activation of murine B cells and macrophages by synthetic lipid A analogues, solubilized with triethylamine and complexed with bovine serum albumin, were investigated in vitro. The analogues used are nonphosphorylated, C-1 or C-4′ monophos-phor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6579fa1b8273f33fe3e45bc9196965b
https://doi.org/10.1002/eji.1830140202
https://doi.org/10.1002/eji.1830140202
Autor:
Takao Kasai, J. Yuzuru Homma
Publikováno v:
The Journal of Antibiotics. 35:343-348
Synergistic effects of peptide and macrolide antibiotics against Pseudomonas aeruginosa were investigated in vitro and in vivo. Synergistic effects were evaluated by estimating the number of viable bacteria at varying intervals in the logarithmic gro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e67255be662dd5deaeb57e5548d992e1
https://doi.org/10.7164/antibiotics.35.343
https://doi.org/10.7164/antibiotics.35.343
Autor:
Ken-ichi Tanamoto, J. Yuzuru Homma
Publikováno v:
The Journal of Biochemistry. 91:741-746
Regions of lipopolysaccharide derived from Pseudomonas aeruginosa essential for pyrogenicity and activation of the proclotting enzyme of the horseshoe crab were examined. Free lipid A with intact fatty acids showed strong pyrogenicity but showed litt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::814f4cbea28c58cb6b15de1f810efa5a
https://doi.org/10.1093/oxfordjournals.jbchem.a133760
https://doi.org/10.1093/oxfordjournals.jbchem.a133760
Autor:
Michiharu Yamamoto, Yasuhiko Kojima, Hiroyuki Yoshimura, Tetsuo Shimamoto, Shoichi Kusumoto, J. Yuzuru Homma, Akihiro Yamamoto, Toru Tsumita, Tesuo Shiba, Masahiro Imoto, Yoshio Kumazawa, Motohiro Matsuura, Ken-ichi Tanamoto, Tatsuji Yasuda, Shiro Kanegasaki
Publikováno v:
European Journal of Biochemistry. 143:237-242
Lipid A analogues were chemically synthesized based on the model structure recently revised, and biological activities of the analogues were tested. The analogue, (beta-1,6)-linked glucosamine disaccharide carrying ester-bound 3-hydroxytetradecanoic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3533a17661904666edd372b8a00d2dde
https://doi.org/10.1111/j.1432-1033.1984.tb08364.x
https://doi.org/10.1111/j.1432-1033.1984.tb08364.x