Tumor necrosis factor- α infliximab inhibits osteoclast formation of peripheral blood mononuclear cells but does not affect periodontal ligament fibroblast-mediated osteoclast formation

Autor: T. J. de Vries, Ton Schoenmaker, J. Yousovich, Vincent Everts, Nina Scheres

Publikováno v: Journal of Periodontal Research, 51(2), 186-195. Blackwell Munksgaard
de Vries, T J, Yousovich, J, Schoenmaker, T, Scheres, N & Everts, V 2016, ' Tumor necrosis factor-α infliximab inhibits osteoclast formation of peripheral blood mononuclear cells but does not affect periodontal ligament fibroblast-mediated osteoclast formation ', Journal of Periodontal Research, vol. 51, no. 2, pp. 186-195 . https://doi.org/10.1111/jre.12297

Background and Objective: The inflammatory cytokine tumor necrosis factor-alpha (TNF-α) is elevated in inflamed periodontal tissues and may contribute to periodontitis progression. TNF-α stimulates formation and activity of osteoclasts, the cells t

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https://doi.org/10.1111/jre.12297