Výsledky vyhledávání - "J. Y. N. Lau"

FK506 in liver transplantation for chronic hepatitis B: In vitro studies on lymphocyte activation and virus replication

Autor: J. M. Tredger, P. Y.N. Wong, Diego Vergani, M. Peakman, George Marinos, Roger Williams, Nikolai V. Naoumov, J. Y. N. Lau

Publikováno v: Liver Transplantation and Surgery. 1:362-370

Recurrence of hepatitis B virus (HBV) in the graft is the major problem for patients with chronic HBV infection undergoing liver transplantation, which could be potentiated by the immunosuppression. In the present study, we used lymphocytes and hepat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5eae7fef2915ff5d98251ed399aac19b
https://doi.org/10.1002/lt.500010605

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Hepatitis C Virus Genotypes 1 and 2 Respond to Interferon-a with Different

Autor: V. Kinetics, M. Kohara, T. Tanaka, K. Tsukiyama-Kohara, S. Tanaka, M. Mizokami, J. Y. N. Lau, N. Hattori

Publikováno v: Journal of Infectious Diseases. 172:934-938

Responses of patients infected with chronic hepatitis C virus (HCV) to interferon-alpha (IFN-alpha) treatment were studied. HCV genotypes were determined by molecular and serologic techniques. Levels of HCV viremia were determined by quantitative rev

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f30d055ca25f7137e08ee5166b4ba484
https://doi.org/10.1093/infdis/172.4.934

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Interferon-α therapy with and without interferon-α priming in patients with chronic hepatitis B infection

Autor: GraemeJ.M. Alexander, Roger Williams, J. Y. N. Lau, Adrian P. Catterall, Helena M. Daniels, Ruth King, I. M. Murray-Lyon

Publikováno v: Journal of Antimicrobial Chemotherapy. 31:777-782

To determine whether a priming course of lymphoblastoid interferon-alpha (IFN-alpha) enhances the efficacy of subsequent IFN-alpha therapy in the treatment of chronic hepatitis B, a randomized trial was conducted to compare IFN-alpha priming (IFN-alp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86d857d8baa14bfec5e0fa259c80dc6b
https://doi.org/10.1093/jac/31.5.777

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Rapid detection of hepatitis B virus DNA in liver tissue by in situ hybridisation and its combination with immunohistochemistry for simultaneous detection of HBV antigens

Autor: Nikolai V. Naoumov, J. Y. N. Lau, Graeme J.M. Alexander, Roger Williams

Publikováno v: Journal of Clinical Pathology. 44:905-908

A rapid technique using a non-radioactive receptor molecule (digoxigenin) for intrahepatic hepatitis B virus (HBV) DNA detection using in situ hybridisation was developed. It can be adapted for use in combination with standard immunohistochemistry fo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::414a23f1d941e79a20f043cb48c346a4
https://doi.org/10.1136/jcp.44.11.905

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Ribavirin induces error-prone replication of GB virus B in primary tamarin hepatocytes

Autor: Zhi Hong, Kathleen M. Brasky, Deborah Chavez, Burton Beames, J. Y. N. Lau, Robert E. Lanford, Bernadette Guerra

Publikováno v: Journal of virology. 75(17)

GB virus B (GBV-B) is the closest relative of hepatitis C virus (HCV) and is an attractive surrogate model for HCV antiviral studies. GBV-B induces an acute, resolving hepatitis in tamarins. Utilizing primary cultures of tamarin hepatocytes, we have

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8888a39d1942827022eb721f10b6eb1
https://pubmed.ncbi.nlm.nih.gov/11483752

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A longitudinal analysis of hepatitis C virus replication following liver transplantation

Autor: Edward Gane, Geert Maertens, J. Y. N. Lau, Roger Williams, K. P. Qian, Bernard Portmann, Mario U. Mondelli, Nikolai V. Naoumov

Publikováno v: Gastroenterology. 110(1)

BACKGROUND & AIMS: The pathogenesis of graft injury in liver transplant recipients with recurrent hepatitis C virus (HCV) infection remains poorly understood. In this study, the relationship between HCV replication, genotype, and the evolution of gra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8914e9aa7bc3e03418598ef3783fd8ee
https://pubmed.ncbi.nlm.nih.gov/8536853

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