Zobrazeno 1 - 10
of 41
pro vyhledávání: '"J. Y. Le Talaer"'
Autor:
Laurent Poulain, M Gignoux, H Crouet, François Sichel, F Bureau, J. Y. Le Talaer, Pascal Gauduchon
Publikováno v:
Cancer Chemotherapy and Pharmacology. 40:385-390
An in vitro study of the combined cytotoxicity of either cisplatin (CDDP) or carboplatin and amphotericin B (AmB) was undertaken on a set of different ovarian carcinoma (IGROVI, IGROVI-C10, OAW42) and peritoneal malignant mesothelioma (CFB-CARP1) cel
Autor:
V Moinet-Hedin, Max Robba, T. Tabka, François Sichel, Jean Charles Lancelot, C. Saturnino, Pascal Gauduchon, B. Letois, J. Y. Le Talaer
Publikováno v:
European Journal of Medicinal Chemistry. 32:113-122
Summary Thirty-seven new 5,11-dimethyl-6 H -pyrido[3,2- b ]carbazole derivatives have been synthesized. These compounds are structurally related to the 5,11-dimethyl-6 H -pyrido[4,3- b ]carbazole antitumor drug ellipticine. They bear either a fluorin
Autor:
C. Boissart, François Sichel, J. C. Lancelot, Pascal Gauduchon, Stéphane Chemtob, A. Tallec, E. Raoult, M. Robba, Christiane Mercier, Véronique André, J. Y. Le Talaer
Publikováno v:
Mutation Research/Genetic Toxicology. 345:11-25
The mutagenicity of 4 ortho-aminonitrocarbazoles and 2 ortho-acetamidonitrocarbazoles was assayed in Salmonella strains TA1538, TA98, TA100, TA1537 and TA1977 and in nitroreductase and acetylase deficient strains TA98NR and TA98/1,8DNP 6 , with and w
Autor:
C. Boissart, C. Saturnino, Véronique André, Pascal Gauduchon, J. C. Lancelot, B. Letois, J. Y. Le Talaer, Sylvain Rault, M. Robba, M. Lechevrel
Publikováno v:
Mutation Research/Genetic Toxicology. 299:63-73
Mononitro, monoamino and monoacetamido carbazoles were assayed for mutagenicity in Salmonella typhimurium strains TA1535, TA1538, TA1537, TA1977, TA98 and TA100, with and without the addition of S9 from phenobarbital-induced rat liver. The role of ba
Autor:
T. Tabka, V Moinet-Hedin, Sylvain Rault, Max Robba, Pascal Gauduchon, Jean Charles Lancelot, B. Letois, J. Y. Le Talaer
Publikováno v:
European Journal of Medicinal Chemistry. 28:721-726
A series of 5,11-dimethyl-6H-pyrido[3,2-b]carbazoles, structurally related to the antitumor drug ellipticine, were synthesized from 3-amino-1,4-dimethyl-9H-carbazole. Among 17 derivatives, bearing various substituents on the pyridine ring, and prelim
Autor:
T. Tabka, E. Bertreux, M. Robba, Sylvain Rault, Pascal Gauduchon, B. Letois, J. Y. Le Talaer, J. C. Lancelot
Publikováno v:
ChemInform. 22
Autor:
B. Letois, J. Y. Le Talaer, T. Tabka, Carmela Saturnino, V Moinet-Hedin, Pascal Gauduchon, M. Robba, François Sichel, J. C. Lancelot
Publikováno v:
ChemInform. 28
Autor:
B. Letois, Jean Charles Lancelot, J. Y. Le Talaer, Pascal Gauduchon, E. Bertreux, Sylvain Rault, T. Tabka, Max Robba
Publikováno v:
European Journal of Medicinal Chemistry. 25:775-784
Resume La synthese d'une serie de 3-nitro et 3-amino-1,4-dimethyl-9H-carbazoles diversement substitues en positions 6 et 8 est decrite. Leur activite cytotoxique, evaluee in vitro au moyen de la culture clonogenique de la leucemie L1210, depend forte
Autor:
J. Y. Le Talaer, A. Tallec, J. C. Lancelot, E. Raoult, François Sichel, Véronique André, C. Boissart, Stéphane Chemtob, Christiane Mercier, Pascal Gauduchon
Publikováno v:
Mutation research. 389(2-3)
The mutagenic potency of nine methylnitrocarbazoles, four methylaminocarbazoles and the methylcarbazole parent compounds was evaluated in Salmonella typhimurium TA98 and TA100, in the absence and presence of S9 isolated from Aroclor-induced rat liver
Publikováno v:
Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie. 312(1)
A cell line, IGROV1, originating from a human ovarian cancer, releases a galactosyltransferase activity in its culture medium during proliferation. The proliferating IGROV1 cells appear as two populations: some cells grow in floating clusters whereas