Zobrazeno 1 - 10
of 71
pro vyhledávání: '"J. Y. Le Talaer"'
Autor:
Laurent Poulain, M Gignoux, H Crouet, François Sichel, F Bureau, J. Y. Le Talaer, Pascal Gauduchon
Publikováno v:
Cancer Chemotherapy and Pharmacology. 40:385-390
An in vitro study of the combined cytotoxicity of either cisplatin (CDDP) or carboplatin and amphotericin B (AmB) was undertaken on a set of different ovarian carcinoma (IGROVI, IGROVI-C10, OAW42) and peritoneal malignant mesothelioma (CFB-CARP1) cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36c03c602de2d6790e949ed972a7992a
https://doi.org/10.1007/s002800050675
https://doi.org/10.1007/s002800050675
Autor:
V Moinet-Hedin, Max Robba, T. Tabka, François Sichel, Jean Charles Lancelot, C. Saturnino, Pascal Gauduchon, B. Letois, J. Y. Le Talaer
Publikováno v:
European Journal of Medicinal Chemistry. 32:113-122
Summary Thirty-seven new 5,11-dimethyl-6 H -pyrido[3,2- b ]carbazole derivatives have been synthesized. These compounds are structurally related to the 5,11-dimethyl-6 H -pyrido[4,3- b ]carbazole antitumor drug ellipticine. They bear either a fluorin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ebfec5cbfc67e01ad96354946b565d76
https://doi.org/10.1016/s0223-5234(97)87537-x
https://doi.org/10.1016/s0223-5234(97)87537-x
Autor:
C. Boissart, François Sichel, J. C. Lancelot, Pascal Gauduchon, Stéphane Chemtob, A. Tallec, E. Raoult, M. Robba, Christiane Mercier, Véronique André, J. Y. Le Talaer
Publikováno v:
Mutation Research/Genetic Toxicology. 345:11-25
The mutagenicity of 4 ortho-aminonitrocarbazoles and 2 ortho-acetamidonitrocarbazoles was assayed in Salmonella strains TA1538, TA98, TA100, TA1537 and TA1977 and in nitroreductase and acetylase deficient strains TA98NR and TA98/1,8DNP 6 , with and w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de9005dfe3536b4f73e56eed75b8de98
https://doi.org/10.1016/0165-1218(95)90066-7
https://doi.org/10.1016/0165-1218(95)90066-7
Autor:
C. Boissart, C. Saturnino, Véronique André, Pascal Gauduchon, J. C. Lancelot, B. Letois, J. Y. Le Talaer, Sylvain Rault, M. Robba, M. Lechevrel
Publikováno v:
Mutation Research/Genetic Toxicology. 299:63-73
Mononitro, monoamino and monoacetamido carbazoles were assayed for mutagenicity in Salmonella typhimurium strains TA1535, TA1538, TA1537, TA1977, TA98 and TA100, with and without the addition of S9 from phenobarbital-induced rat liver. The role of ba
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::03f96c52d6cae8eb5016588e33571066
https://doi.org/10.1016/0165-1218(93)90120-3
https://doi.org/10.1016/0165-1218(93)90120-3
Autor:
T. Tabka, V Moinet-Hedin, Sylvain Rault, Max Robba, Pascal Gauduchon, Jean Charles Lancelot, B. Letois, J. Y. Le Talaer
Publikováno v:
European Journal of Medicinal Chemistry. 28:721-726
A series of 5,11-dimethyl-6H-pyrido[3,2-b]carbazoles, structurally related to the antitumor drug ellipticine, were synthesized from 3-amino-1,4-dimethyl-9H-carbazole. Among 17 derivatives, bearing various substituents on the pyridine ring, and prelim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::720bbcefbaa4f8c093915de2324eb802
https://doi.org/10.1016/0223-5234(93)90032-a
https://doi.org/10.1016/0223-5234(93)90032-a
Autor:
T. Tabka, E. Bertreux, M. Robba, Sylvain Rault, Pascal Gauduchon, B. Letois, J. Y. Le Talaer, J. C. Lancelot
Publikováno v:
ChemInform. 22
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::38249d765d290de789ff51597b08c8f4
https://doi.org/10.1002/chin.199115163
https://doi.org/10.1002/chin.199115163
Autor:
B. Letois, J. Y. Le Talaer, T. Tabka, Carmela Saturnino, V Moinet-Hedin, Pascal Gauduchon, M. Robba, François Sichel, J. C. Lancelot
Publikováno v:
ChemInform. 28
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd386d999f0e4ffac69e13fbf7be042e
https://doi.org/10.1002/chin.199725140
https://doi.org/10.1002/chin.199725140
Autor:
B. Letois, Jean Charles Lancelot, J. Y. Le Talaer, Pascal Gauduchon, E. Bertreux, Sylvain Rault, T. Tabka, Max Robba
Publikováno v:
European Journal of Medicinal Chemistry. 25:775-784
Resume La synthese d'une serie de 3-nitro et 3-amino-1,4-dimethyl-9H-carbazoles diversement substitues en positions 6 et 8 est decrite. Leur activite cytotoxique, evaluee in vitro au moyen de la culture clonogenique de la leucemie L1210, depend forte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::781bd28a80074cebb79abe883b233a07
https://doi.org/10.1016/0223-5234(90)90197-b
https://doi.org/10.1016/0223-5234(90)90197-b
Autor:
J. Y. Le Talaer, A. Tallec, J. C. Lancelot, E. Raoult, François Sichel, Véronique André, C. Boissart, Stéphane Chemtob, Christiane Mercier, Pascal Gauduchon
Publikováno v:
Mutation research. 389(2-3)
The mutagenic potency of nine methylnitrocarbazoles, four methylaminocarbazoles and the methylcarbazole parent compounds was evaluated in Salmonella typhimurium TA98 and TA100, in the absence and presence of S9 isolated from Aroclor-induced rat liver
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83c651992ba669091d847906850cefb1
https://pubmed.ncbi.nlm.nih.gov/9093391
https://pubmed.ncbi.nlm.nih.gov/9093391
Publikováno v:
Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie. 312(1)
A cell line, IGROV1, originating from a human ovarian cancer, releases a galactosyltransferase activity in its culture medium during proliferation. The proliferating IGROV1 cells appear as two populations: some cells grow in floating clusters whereas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::12a87a5fbadd509242ef346593ac2d87
https://pubmed.ncbi.nlm.nih.gov/1900729
https://pubmed.ncbi.nlm.nih.gov/1900729