Zobrazeno 1 - 10
of 13
pro vyhledávání: '"J. Y. C. Ma"'
Autor:
Joseph D. Brain, Vincent Castranova, Georgios Pyrgiotakis, Samuel Gass, Walt McKinney, William T. Goldsmith, Joel M. Cohen, David G. Frazer, Diane Schwegler-Berry, Philip Demokritou, J. Y. C. Ma
Publikováno v:
Nanotoxicology. 7:1338-1350
Nanoscale CeO₂ is increasingly used for industrial and commercial applications, including catalysis, UV-shielding and as an additive in various nanocomposites. Because of its increasing potential for consumer and occupational exposures, a comprehen
Autor:
Vincent Castranova, Mark Barger, J. Y. C. Ma, Robert R. Mercer, James F. Scabilloni, Diane Schwegler-Berry, Joseph K. H. Ma
Publikováno v:
Toxicology and Applied Pharmacology. 262:255-264
Cerium compounds have been used as a diesel engine catalyst to lower the mass of diesel exhaust particles, but are emitted as cerium oxide (CeO(2)) nanoparticles in the diesel exhaust. In a previous study, we have demonstrated a wide range of CeO(2)-
Autor:
Vince Castranova, Joseph K. H. Ma, Lyndell Millecchia, J. Y. C. Ma, Mark Barger, Diane Schwegler-Berry, Robert R. Mercer, Hongwen Zhao
Publikováno v:
Journal of Toxicology and Environmental Health, Part A. 72:560-570
Pulmonary responses to diesel exhaust particles (DEP) exposure are mediated through enhanced production of reactive oxygen species (ROS) and nitric oxide (NO) by alveolar macrophages (AM). The current study examined the differential roles of ROS and
Autor:
Mark Barger, Lori A. Battelli, Michael L. Kashon, Joginder Nath, Mohamed Ghanem, J. Y. C. Ma, Vincent Castranova, Ann F. Hubbs, Dale W. Porter, Val Vallyathan
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 31:171-183
Cytochrome P4501A1 (CYP1A1) metabolizes polycyclic aromatic hydrocarbons in cigarette smoke to DNA-binding reactive intermediates associated with carcinogenesis. Epidemiologic studies indicate that the majority of coal miners are smokers but have a l
Autor:
Mark Barger, Leon Butterworth, Hui-Min Yang, Joseph K. H. Ma, J. Y. C. Ma, B R Roberts, Castranova, Jim Antonini
Publikováno v:
Environmental Health Perspectives
In this study, we tested the hypothesis that exposure to diesel exhaust particles (DEP) may increase susceptibility of the host to pulmonary infection. Male Sprague-Dawley rats received a single dose of DEP (5 mg/kg), carbon black (CB, 5 mg/kg), or s
Publikováno v:
Archives of Toxicology. 74:452-459
Objective: The present study was carried out to characterize the effects of in vitro exposure to paving asphalt fume condensate (AFC) on alveolar macrophage (AM) functions and to monitor acute pulmonary responses to in vivo AFC exposure in rats. Meth
Publikováno v:
Journal of Toxicology and Environmental Health, Part A. 57:247-266
Animals exposed to silica or bleomycin (BLM) develop pulmonary fibrosis. Tetrandrine (TT) has been shown to inhibit stimulant-induced macrophage respiratory burst and effectively reduce silica-induced lung injury. The present study employed TT as a p
Autor:
Daniel E. Banks, Vincent Castranova, V. Vallyathan, E. B. Flink, M. Billie, J. Y. C. Ma, Mark Barger, Nar S. Dalal, Harakh V. Dedhia
Publikováno v:
Journal of Toxicology and Environmental Health. 40:1-13
Exposure of rats to hyperoxia (100% oxygen for 64 h) resulted in striking alterations in the properties of samples obtained by bronchoalveolar lavage. The yield of neutrophils, lymphocytes, and red blood cells was increased, while the number of harve
Autor:
Joseph K. H. Ma, Murali Rao, Terence Meighan, Mark Barger, J. Y. C. Ma, Diane Schwegler-Berry, Vincent Castranova, Robert R. Mercer, Hongwen Zhao
Publikováno v:
Nanotoxicology. 5(3)
The use of cerium compounds as diesel fuel catalyst results in the emission of cerium oxide nanoparticles (CeO2) in the exhaust. This study characterized the potential effects of CeO2 exposure on lung toxicity. Male Sprague Dawley rats were exposed t
Publikováno v:
Journal of toxicology and environmental health. Part A. 67(17)
Tumor necrosis factor-alpha (TNF-a) is produced by alveolar macrophages (AM) in response to bleomycin (BLM) exposure. This cytokine has been linked to BLM-induced pulmonary inflammation, an early drug effect, and to lung fibrosis, the ultimate toxic