Zobrazeno 1 - 10
of 30
pro vyhledávání: '"J. Winny Yun"'
Publikováno v:
Pathophysiology, Vol 28, Iss 1, Pp 64-75 (2021)
Alzheimer’s Disease (AD) is a neurodegenerative condition characterized both by the presence of tau protein neurofibrillary tangles and amyloid beta (Aβ) containing extracellular “plaques”. The cleavage of amyloid precursor protein (APP) yield
Externí odkaz:
https://doaj.org/article/4c315648e2384f15a1dd3fa702bd7d70
Autor:
Christen J. Boyer, David H. Ballard, Mansoureh Barzegar, J. Winny Yun, Jennifer E. Woerner, Ghali E. Ghali, Moheb Boktor, Yuping Wang, J. Steven Alexander
Publikováno v:
3D Printing in Medicine, Vol 4, Iss 1, Pp 1-6 (2018)
Abstract Background Three-dimensional (3D) cell cultures and 3D bioprinting have recently gained attention based on their multiple advantages over two-dimensional (2D) cell cultures, which have less translational potential to recapitulate human physi
Externí odkaz:
https://doaj.org/article/8084df71b8d44fb08df7943a30315c1c
Autor:
Mansoureh Barzegar, Yuping Wang, Randa S. Eshaq, J. Winny Yun, Christen J. Boyer, Sergio G. Cananzi, Luke A. White, Oleg Chernyshev, Roger E. Kelley, Alireza Minagar, Karen Y. Stokes, Xiao-Hong Lu, Jonathan S. Alexander
Publikováno v:
EBioMedicine, Vol 63, Iss , Pp 103161- (2021)
Background: Besides long-term trans-differentiation into neural cells, benefits of stem cell therapy (SCT) in ischemic stroke may include secretion of protective factors, which partly reflects extracellular vesicle (EVs) released by stem cell. Howeve
Externí odkaz:
https://doaj.org/article/d89ea5f8faa2468dbd0a87084b80f2be
Autor:
J. Winny Yun, Mansoureh Barzegar, Christen J. Boyer, Alireza Minagar, Pierre-Olivier Couraud, Jonathan Steven Alexander
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Microparticles (MP) are regarded both as biomarkers and mediators of many forms of pathology, including neurovascular inflammation. Here, we characterized vectorial release of apical and basolateral MPs (AMPs and BMPs) from control and TNF-α/IFN-γ
Externí odkaz:
https://doaj.org/article/db57e76a5ae24ec5a40ecb303f99f862
Autor:
Seiichi Omura, Eiichiro Kawai, Fumitaka Sato, Nicholas E. Martinez, Alireza Minagar, Mahmoud Al-Kofahi, J. Winny Yun, Urska Cvek, Marjan Trutschl, J. Steven Alexander, Ikuo Tsunoda
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Theiler's murine encephalomyelitis virus (TMEV) induces different diseases in the central nervous system (CNS) and heart, depending on the mouse strains and time course, with cytokines playing key roles for viral clearance and immune-mediated patholo
Externí odkaz:
https://doaj.org/article/5213ef869cde453ba1e176347a57a3be
Autor:
Sergio G. Cananzi, Christen J. Boyer, Ramon Farré, Alireza Minagar, Roger E. Kelley, Jonathan Steven Alexander, J. Winny Yun, Luke A. White, Isaac Almendros, Oleg Chernyshev, Mansoureh Barzegar
Publikováno v:
Sleep Medicine. 67:278-285
Study objectives Obstructive sleep apnea (OSA) is a sleep disorder caused by transient obstruction of the upper airway and results in intermittent hypoxia, sleep fragmentation, sympathetic nervous system activation, and arousal which can have an adve
Autor:
Felix Becker, J. Winny Yun, Dana L. Hasselschwert, Luke A. White, Charles N. Serhan, Paul C. Norris, Melany Musso, John A. Vanchiere, Emily Romero, Jason E. Goetzmann, Beth K. Dray, Felicity N. E. Gavins, Jane Fontenot, J. Steven Alexander
Publikováno v:
Am J Pathol
Changes in the intestinal lymphatic vascular system, such as lymphatic obstruction, are characteristic features of inflammatory bowel diseases. The lymphatic vasculature forms a conduit to enable resolution of inflammation; this process is driven by
Autor:
Jennifer E. Woerner, Christen J. Boyer, Mansoureh Barzegar, Yuping Wang, J. Winny Yun, David H. Ballard, Moheb Boktor, Ghali E. Ghali, J. Steven Alexander
Publikováno v:
3D Printing in Medicine, Vol 4, Iss 1, Pp 1-6 (2018)
3D Printing in Medicine
3D Printing in Medicine
Background Three-dimensional (3D) cell cultures and 3D bioprinting have recently gained attention based on their multiple advantages over two-dimensional (2D) cell cultures, which have less translational potential to recapitulate human physiology. 3D
Autor:
David J. Rios, Theodore A. Tyler, Gabriel S. Jackson, Jonathan S. Alexander, Judith L. Palmer Castor, Alireza Minagar, Geoffrey E. Purdum, Trevor Percival Castor, Maria I. Vizcanio, Ping Yi, Kasey Jackson, Lisa Schrott, J. Winny Yun, Christopher Webb
Publikováno v:
Current Alzheimer research. 17(14)
Background: Alzheimer’s disease (AD) animal models have revealed neuroprotective actions of Bryostatin-1 mediated by activation of novel PKC isoforms, suppression of beta-amyloid and downregulation of inflammatory and angiogenic events, making Bryo
The lymphatic system plays an integral role in immune control, lipid metabolism, and fluid homeostasis. This chapter focuses on the lymphatics in the context of the central nervous system (CNS). The brain itself is a complex organ. Despite comprising
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::000f90a3d3780d208e6530fee8795405
https://doi.org/10.1016/b978-0-12-815645-2.00005-8
https://doi.org/10.1016/b978-0-12-815645-2.00005-8