Zobrazeno 1 - 10
of 2 629
pro vyhledávání: '"J. Will"'
Autor:
Jacob K. Kenny, Sasha R. Neefe, David G. Brandner, Michael L. Stone, Renee M. Happs, Ivan Kumaniaev, William P. Mounfield, Anne E. Harman-Ware, Katrien M. Devos, Thomas H. Pendergast, J. Will Medlin, Yuriy Román-Leshkov, Gregg T. Beckham
Publikováno v:
JACS Au, Vol 4, Iss 6, Pp 2173-2187 (2024)
Externí odkaz:
https://doaj.org/article/31fd14f697a542b5925277fcc76396f9
Publikováno v:
Green Energy & Environment, Vol 7, Iss 6, Pp 1263-1269 (2022)
Atomically dispersed precious metal catalysts maximize atom efficiency and exhibit unique reactivity. However, they are susceptible to sintering. Catalytic reactions occurring in reducing environments tend to result in atomically dispersed metals sin
Externí odkaz:
https://doaj.org/article/a916b7d6354c47a8a1bf1328738ee7f1
Autor:
Alec G. Trub, Gregory R. Wagner, Kristin A. Anderson, Scott B. Crown, Guo-Fang Zhang, J. Will Thompson, Olga R. Ilkayeva, Robert D. Stevens, Paul A. Grimsrud, Rhushikesh A. Kulkarni, Donald S. Backos, Jordan L. Meier, Matthew D. Hirschey
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Statin therapy is associated with numerous cellular effects. Here, the authors show that statin treatment increases post-translational modifications on fatty acid synthase in the active site, revealing communication between the cholesterol and lipid
Externí odkaz:
https://doaj.org/article/6da5de5206424c06a24ccdd0b2b403ff
Autor:
Pauline McLoone, Aizhan Zhumbayeva, Sofiya Yunussova, Yerkhat Kaliyev, Ludmila Yevstafeva, Susan Verrall, Julie Sungurtas, Ceri Austin, J. Will Allwood, Gordon J. McDougall
Publikováno v:
BMC Complementary Medicine and Therapies, Vol 21, Iss 1, Pp 1-11 (2021)
Abstract Background Antimicrobial drug resistance is a major public health threat that can render infections including wound and skin infections untreatable. The discovery of new antimicrobials is critical. Approaches to discover novel antimicrobial
Externí odkaz:
https://doaj.org/article/547d6edf25c3411f93aa2f7df83b1790
Autor:
Charles D. Giamberardino, Wiley A. Schell, Jennifer L. Tenor, Dena L. Toffaletti, Julia R. Palmucci, Choiselle Marius, Jane-Valeriane K. Boua, Quinlyn Soltow, Robert Mansbach, M. Arthur Moseley, J. Will Thompson, Laura G. Dubois, William Hope, John R. Perfect, Karen Joy Shaw
Publikováno v:
mBio, Vol 13, Iss 6 (2022)
ABSTRACT Cryptococcal Meningitis (CM) is uniformly fatal if not treated, and treatment options are limited. We previously reported on the activity of APX2096, the prodrug of the novel Gwt1 inhibitor APX2039, in a mouse model of CM. Here, we investiga
Externí odkaz:
https://doaj.org/article/12c94fc2bb48423287573f9192ce65ce
Autor:
Raymond J. Langley, Marie E. Migaud, Lori Flores, J. Will Thompson, Elizabeth A. Kean, Murphy M. Mostellar, Matthew Mowry, Patrick Luckett, Lina D. Purcell, James Lovato, Sheetal Gandotra, Ryan Benton, D. Clark Files, Kevin S. Harrod, Mark N. Gillespie, Peter E. Morris
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Acute respiratory failure (ARF) requiring mechanical ventilation, a complicating factor in sepsis and other disorders, is associated with high morbidity and mortality. Despite its severity and prevalence, treatment options are limited. In li
Externí odkaz:
https://doaj.org/article/ebfe182cebd342acb30834ed1318f664
Autor:
Siamak MahmoudianDehkordi, Ahmed T. Ahmed, Sudeepa Bhattacharyya, Xianlin Han, Rebecca A. Baillie, Matthias Arnold, Michelle K. Skime, Lisa St. John-Williams, M. Arthur Moseley, J. Will Thompson, Gregory Louie, Patricio Riva-Posse, W. Edward Craighead, William McDonald, Ranga Krishnan, A. John Rush, Mark A. Frye, Boadie W. Dunlop, Richard M. Weinshilboum, Rima Kaddurah-Daouk, The Mood Disorders Precision Medicine Consortium (MDPMC)
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Selective serotonin reuptake inhibitors (SSRIs) are the first-line treatment for major depressive disorder (MDD), yet their mechanisms of action are not fully understood and their therapeutic benefit varies among individuals. We used a targe
Externí odkaz:
https://doaj.org/article/9ab1fb8fadf043bab4c692f343ee6618
Autor:
Matthias Arnold, Kwangsik Nho, Alexandra Kueider-Paisley, Tyler Massaro, Kevin Huynh, Barbara Brauner, Siamak MahmoudianDehkordi, Gregory Louie, M. Arthur Moseley, J. Will Thompson, Lisa St John-Williams, Jessica D. Tenenbaum, Colette Blach, Rui Chang, Roberta D. Brinton, Rebecca Baillie, Xianlin Han, John Q. Trojanowski, Leslie M. Shaw, Ralph Martins, Michael W. Weiner, Eugenia Trushina, Jon B. Toledo, Peter J. Meikle, David A. Bennett, Jan Krumsiek, P. Murali Doraiswamy, Andrew J. Saykin, Rima Kaddurah-Daouk, Gabi Kastenmüller
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Sex and the APOE ε4 genotype are important risk factors for late-onset Alzheimer’s disease. In the current study, the authors investigate how sex and APOE ε4 genotype modify the association between Alzheimer’s disease biomarkers and metabolites
Externí odkaz:
https://doaj.org/article/4622f4afa16f4c509372906b7b40a13c
Autor:
Kevin A. Friede, Margaret M. Infeld, Ru San Tan, Holly J. Knickerbocker, Rachel A. Myers, Laura G. Dubois, J. Will Thompson, Rima Kaddurah‐Daouk, Geoffrey S. Ginsburg, Thomas L. Ortel, Deepak Voora
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 9, Iss 14 (2020)
Background There are sex differences in the efficacy and safety of aspirin for the prevention of myocardial infarction and stroke. Whether this is explained by underlying differences in platelet reactivity and aspirin response remains poorly understo
Externí odkaz:
https://doaj.org/article/dd149699ca50412cae2156f95b0d1986
Autor:
Lucas D. Ellis, Surya T. Parker, Jeremy Hu, Sarah F. Zaccarine, Michael J. Stellato, Hans H. Funke, Carsten Sievers, Svitlana Pylypenko, John L. Falconer, J. Will Medlin
Publikováno v:
Cell Reports Physical Science, Vol 1, Iss 4, Pp 100036- (2020)
Summary: The distillation of light gases requires significant energy inputs. Sorbents could alleviate this issue, but they must be able to separate molecules of similar size and chemical functionality. Here, we report the enhanced separations of gase
Externí odkaz:
https://doaj.org/article/3c1cd91cf9544bf4ac096b213ba7b76d