Zobrazeno 1 - 10
of 2 970
pro vyhledávání: '"J. Whelan"'
Autor:
Todd Gouin, Michael J. Whelan
Publikováno v:
Microplastics and Nanoplastics, Vol 4, Iss 1, Pp 1-16 (2024)
Abstract Microplastic particles (MPs) represent potential hazards for humans and wildlife, including as vectors for chemical exposure (e.g. plastic additives and pollutants sorbed from the surrounding environment). The leaching of chemicals from MPs
Externí odkaz:
https://doaj.org/article/22a6121393514fc3af109de4824f3d6d
Autor:
Catherine A. Doyle, Gregory W. Busey, Wesley H. Iobst, Volker Kiessling, Chloe Renken, Hansa Doppalapudi, Marta E. Stremska, Mohan C. Manjegowda, Mohd Arish, Weiming Wang, Shardul Naphade, Joel Kennedy, Louis-Marie Bloyet, Cassandra E. Thompson, Paul W. Rothlauf, Eric J. Stipes, Sean P. J. Whelan, Lukas K. Tamm, Alex J. B. Kreutzberger, Jie Sun, Bimal N. Desai
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract The majority of viruses classified as pandemic threats are enveloped viruses which enter the cell through receptor-mediated endocytosis and take advantage of endosomal acidification to activate their fusion machinery. Here we report that the
Externí odkaz:
https://doaj.org/article/dee6605d5bdc48a684b5ee4df122fe09
Autor:
S. Harkisoen, J.E. Arends, J.A.R. van den Hoek, J. Whelan, K.J. van Erpecum, G.J. Boland, A.I.M. Hoepelman
Publikováno v:
International Journal of Infectious Diseases, Vol 29, Iss C, Pp 133-138 (2014)
Background: Some studies done in Asian patients have shown that serum levels of hepatitis B virus (HBV) DNA predict the development of cirrhosis. However, it is unclear whether this also applies for non-Asian patients. This study investigated histori
Externí odkaz:
https://doaj.org/article/600d9c0b41274f858debac99dc2715b8
Publikováno v:
Sarcoma, Vol 7, Iss 1, Pp 13-17 (2003)
Purpose. The prognosis for patients with Ewing's tumours who have metastases at presentation or who are refractory to standard chemotherapy regimens remains poor. There is therefore a need to evaluate the role of new agents. This report describes the
Externí odkaz:
https://doaj.org/article/b40817f50b6d46c9a726fc1a65143018
Autor:
Jennifer B. Permuth, Margaret A. Park, Dung-Tsa Chen, Toni Basinski, Benjamin D. Powers, Clement K. Gwede, Kaleena B. Dezsi, Maria Gomez, Shraddha L. Vyas, Tiago Biachi, Elena M. Cortizas, Sylvia Crowder, Maria Genilo-Delgado, B.Lee Green, Anna Greene, Christopher Gregg, Sarah E. Hoffe, Kun Jiang, Bora Kim, Vanitha Vasudevan, Jeronimo Garcialopez De Llano, Anjana A. Menon, Qianxing Mo, Lina M. MorenoUrazan, Shaffer Mok, Nathan Parker, Sahana Rajasekhara, Ghulam Rasool, Andrew Sinnamon, Lauren Sparks, Paul A. Stewart, Kenneth Tardif, Alexandra F. Tassielli, Jamie K. Teer, Dan Viet Tran, Kea L. Turner, Susan T. Vadaparampil, Christopher J. Whelan, Wade G. Douglas, Vic Velanovich, Andreas Karachristos, Adrian Legaspi, Kenneth Meredith, Manual A. Molina-Vega, Kevin L. Huguet, Juan P. Arnoletti, Mark Bloomston, Jose Trevino, Nipun B. Merchant, Jose M. Pimiento, Pamela J. Hodul, Mokenge Malafa, Jason Fleming, Sarah M. Judge, Daniel K. Jeong, Andrew Judge
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
IntroductionCancer-associated cachexia (CC) is a progressive syndrome characterized by unintentional weight loss, muscle atrophy, fatigue, and poor outcomes that affects most patients with pancreatic ductal adenocarcinoma (PDAC). The ability to ident
Externí odkaz:
https://doaj.org/article/99b382aea6824ea3b6624e0a14f602fd
Autor:
Amelia B. Shaw, Hiu Nam Tse, Owen Byford, Grace Plahe, Alex Moon-Walker, Samantha E. Hover, Erica Ollmann Saphire, Sean P. J. Whelan, Jamel Mankouri, Juan Fontana, John N. Barr
Publikováno v:
mBio, Vol 15, Iss 7 (2024)
ABSTRACT Lymphocytic choriomeningitis virus (LCMV) is an enveloped and segmented negative-sense RNA virus classified within the Arenaviridae family of the Bunyavirales order. LCMV is associated with fatal disease in immunocompromised populations and,
Externí odkaz:
https://doaj.org/article/6df5a69e4c1d4c89b36dd639fa6325a6
Publikováno v:
BioTechniques, Vol 26, Iss 2, Pp 290-300 (1999)
A fluorescent-based quantitative PCR assay to measure the percentage of the common deletion in rat mitochondria is reported. The amount of the common deletion is measured relative to the amount of total mitochondrial (mt)DNA. The use of a heterologou
Externí odkaz:
https://doaj.org/article/e41324a664594cffacc47dac1b697880
Autor:
Sandeep Sharma, Cecilia A. Badenhorst, Donovan M. Ashby, Stephanie A. Di Vito, Michelle A. Tran, Zahra Ghavasieh, Gurleen K. Grewal, Cole R. Belway, Alexander McGirr, Patrick J. Whelan
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract The cuneiform nucleus (CnF) regulates locomotor activity, which is canonically viewed as being primarily involved in initiating locomotion and regulating speed. Recent research shows greater context dependency in the locomotor functions of t
Externí odkaz:
https://doaj.org/article/1c74346562b3406a8373f34dd6788ab5
Autor:
J. Whelan, T. Pettman, P. Love, A. Romanus, K. Bolton, E. Smith, T. Gill, J. Coveney, E. Waters, S. Allender
Publikováno v:
Journal of Nutrition & Intermediary Metabolism, Vol 1, Iss C, p 38 (2014)
Externí odkaz:
https://doaj.org/article/66fe5eecdc534e9d9523b01c15dd656b
Autor:
Wenjuan Dong, Jing Wang, Lei Tian, Jianying Zhang, Erik W. Settles, Chao Qin, Daniel R. Steinken-Kollath, Ashley N. Itogawa, Kimberly R. Celona, Jinhee Yi, Mitchell Bryant, Heather Mead, Sierra A. Jaramillo, Hongjia Lu, Aimin Li, Ross E. Zumwalt, Sanjeet Dadwal, Pinghui Feng, Weiming Yuan, Sean P. J. Whelan, Paul S. Keim, Bridget Marie Barker, Michael A. Caligiuri, Jianhua Yu
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
The serine protease factor Xa (FXa) is upregulated in COVID-19 patients and functions in the coagulation pathway. Here, Dong et al characterise the basis of its antiviral activity in the context of SARS-CoV-2 pandemic variants.
Externí odkaz:
https://doaj.org/article/b9e60e8540004b07b41e6a1c7eaa4a58