Zobrazeno 1 - 10
of 473
pro vyhledávání: '"J. Whaley"'
Autor:
Alison Schaefer, Bing Yang, Holly A. Schroeder, Dimple Harit, Mike S. Humphry, Larry Zeitlin, Kevin J. Whaley, Jacques Ravel, William A. Fischer, Samuel K. Lai
Publikováno v:
Emerging Microbes and Infections, Vol 13, Iss 1 (2024)
ABSTRACTVaginal transmission from semen of male Ebola virus (EBOV) survivors has been implicated as a potential origin of Ebola virus disease (EVD) outbreaks. While EBOV in semen must traverse cervicovaginal mucus (CVM) to reach target cells, the beh
Externí odkaz:
https://doaj.org/article/0b91368b024b4ae7a579ea704274de58
Autor:
Kelly J. Whaley-Martin, Lin-Xing Chen, Tara Colenbrander Nelson, Jennifer Gordon, Rose Kantor, Lauren E. Twible, Stephanie Marshall, Sam McGarry, Laura Rossi, Benoit Bessette, Christian Baron, Simon Apte, Jillian F. Banfield, Lesley A. Warren
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract The acidification of water in mining areas is a global environmental issue primarily catalyzed by sulfur-oxidizing bacteria (SOB). Little is known about microbial sulfur cycling in circumneutral pH mine tailing impoundment waters. Here we in
Externí odkaz:
https://doaj.org/article/4a9eae705b424b16b8cfed6b4abff5fc
Autor:
Ellena Nador, Chaoshuang Xia, Philip J. Santangelo, Kevin J. Whaley, Catherine E. Costello, Deborah J. Anderson
Publikováno v:
Antibodies, Vol 13, Iss 1, p 17 (2024)
IgG Fc N-glycosylation is necessary for effector functions and is an important component of quality control. The choice of antibody manufacturing platform has the potential to significantly influence the Fc glycans of an antibody and consequently alt
Externí odkaz:
https://doaj.org/article/f4115ee49a3541d4afd575326cb5cb11
Autor:
Dustin W. Currie, Melisa M. Shah, Phillip P. Salvatore, Laura Ford, Melissa J. Whaley, Jennifer Meece, Lynn Ivacic, Natalie J. Thornburg, Azaibi Tamin, Jennifer L. Harcourt, Jennifer Folster, Magdalena Medrzycki, Shilpi Jain, Phili Wong, Kimberly Goffard, Douglas Gieryn, Juliana Kahrs, Kimberly Langolf, Tara Zochert, Christopher H. Hsu, Hannah L. Kirking, Jacqueline E. Tate
Publikováno v:
Emerging Infectious Diseases, Vol 28, Iss 3, Pp 717-720 (2022)
We assessed the relationship between antigen and reverse transcription PCR (RT-PCR) test positivity and successful virus isolation. We found that antigen test results were more predictive of virus recovery than RT-PCR results. However, virus was isol
Externí odkaz:
https://doaj.org/article/f0d243cfc5894d9b85f43d3f2f5ab4e5
Autor:
Emilie Mausser, Ellena Nador, Joseph A Politch, Michael R Pauly, Jai G Marathe, Thomas R Moench, Larry Zeitlin, Kevin J Whaley, Deborah J Anderson
Publikováno v:
PLoS ONE, Vol 18, Iss 3, p e0282147 (2023)
High rates of unintended pregnancies worldwide indicate a need for more accessible and acceptable methods of contraception. We have developed a monoclonal antibody, the Human Contraception Antibody (HCA), for use by women in vaginal films and rings f
Externí odkaz:
https://doaj.org/article/be5acf215cfe4c2b96bdb4513195bae6
Autor:
Kelsi Swope, Josh Morton, Gregory P. Pogue, Leigh Burden, Nicholas Partain, Steve Hume, John Shepherd, Carrie A. Simpson, Miles B. Brennan, Thomas C. Furman, Sheila Kingrey-Gebe, Theresa Martinez, Jim McDonough, Michael H. Pauly, Kevin J. Whaley, Larry Zeitlin, Barry Bratcher, Hugh Haydon
Publikováno v:
mAbs, Vol 14, Iss 1 (2022)
The ongoing SARS-CoV-2 coronavirus pandemic of 2020–2021 underscores the need for manufacturing platforms that can rapidly produce monoclonal antibody (mAb) therapies. As reported here, a platform based on Nicotiana benthamiana produced mAb therape
Externí odkaz:
https://doaj.org/article/0444f122130744d095e196c092b78bd8
Autor:
Pirkko Suihkonen, Lindsay J. Whaley
The languages of Europe and North and Central Asia provide a rich variety of data. In this volume, some articles are summaries of large areal typological research projects, and some articles focus on structures or constructions in a single language.
Autor:
Kevin J Whaley, Larry Zeitlin
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 18, Iss 2 (2022)
This review focuses on the emerging monoclonal antibody market for infectious diseases and the metric ton scale manufacturing requirements to meet global demand. Increasing access to existing antibody-based products coupled with the unmet need in inf
Externí odkaz:
https://doaj.org/article/18e705d77c1c49f3b407847b94f3f1b6
Autor:
Melissa J. Whaley, Jeni T. Vuong, Nadav Topaz, How-Yi Chang, Jennifer Dolan Thomas, Laurel T. Jenkins, Fang Hu, Susanna Schmink, Evelene Steward-Clark, Marsenia Mathis, Lorraine D. Rodriguez-Rivera, Adam C. Retchless, Sandeep J. Joseph, Alexander Chen, Anna M. Acosta, Lucy McNamara, Heidi M. Soeters, Sarah Mbaeyi, Henju Marjuki, Xin Wang
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
In January and February 2015, Neisseria meningitidis serogroup B (NmB) outbreaks occurred at two universities in the United States, and mass vaccination campaigns using MenB vaccines were initiated as part of a public health response. Meningococcal c
Externí odkaz:
https://doaj.org/article/3782a50a58dd4c75a594217904cf413e
Autor:
Gabriela Baldeon-Vaca, Jai G. Marathe, Joseph A. Politch, Emilie Mausser, Jeffrey Pudney, James Doud, Ellena Nador, Larry Zeitlin, Michael Pauly, Thomas R. Moench, Miles Brennan, Kevin J. Whaley, Deborah J. Anderson
Publikováno v:
EBioMedicine, Vol 69, Iss , Pp 103478- (2021)
Background: Approximately 40% of human pregnancies are unintended, indicating a need for more acceptable effective contraception methods. New antibody production systems make it possible to manufacture reagent-grade human monoclonal antibodies (mAbs)
Externí odkaz:
https://doaj.org/article/f960369930a04b50a35050bf6a2ee689