Missense mutations in PIEZO1, which encodes the Piezo1 mechanosensor protein, define Er red blood cell antigens

Autor: Vanja Karamatic Crew, Louise A. Tilley, Timothy J. Satchwell, Samah A. AlSubhi, Benjamin Jones, Frances A. Spring, Piers J. Walser, Catarina Martins Freire, Nicoletta Murciano, Maria Giustina Rotordam, Svenja J. Woestmann, Marwa Hamed, Reem Alradwan, Mouza AlKhrousey, Ian Skidmore, Sarah Lewis, Shimon Hussain, Jane Jackson, Tom Latham, Mark D. Kilby, William Lester, Nadine Becker, Markus Rapedius, Ashley M. Toye, Nicole M. Thornton

Publikováno v: Karamatic Crew, V, Tilley, L A, Satchwell, T, Alsubhi, S A O, Toye, A M & Thornton, N M 2023, ' Missense mutations in PIEZO1, which encodes the Piezo1 mechanosensor protein, define Er red blood cell antigens ', Blood, vol. 141, no. 2, pp. 135-146 . https://doi.org/10.1182/blood.2022016504

Despite the identification of the high-incidence red cell antigen Era nearly 40 years ago, the molecular background of this antigen, together with the other 2 members of the Er blood group collection, has yet to be elucidated. Whole exome and Sanger

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19f3e0486bd0446b7520977b7df82c7c
https://doi.org/10.1182/blood.2022016504

Lessons learned from the implementation of a video health coaching technology intervention to improve self-care of family caregivers of adults with heart failure

Autor: Michael A Stawnychy, Tracie J Walser, Kathryn H. Bowles, Gladys Thomas, Barbara Riegel, Karen B. Hirschman, Brooke Shepard, Lydia Garcia‐Gonzalez

Publikováno v: Res Nurs Health

Individuals with heart failure (HF) typically live in the community and are cared for at home by family caregivers. These caregivers often lack supportive services and the time to access those services when available. Technology can play a role in co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a012b88c2fa4356d82a57a17746f3f69
https://pubmed.ncbi.nlm.nih.gov/33341950

Challenges Using Technology in a Health Coaching Intervention, Early Lessons Learned

Autor: Barbara Riegel, Kathryn H. Bowles, Brooke Shepard, Karen B. Hirschman, Lydia Elena Garcia, Tracie J Walser, Gladys Thomas, Michael A Stawnychy

Publikováno v: Innovation in Aging

Technology provides opportunities to engage with those who are too busy, overwhelmed, or distant for face-to-face interventions, such as lay caregivers of adults with heart failure. While testing the efficacy of virtual health coaching for caregivers

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0186aa7f6c7e7cda2cb19088a5739ddd
https://doi.org/10.1093/geroni/igaa057.2255

MURC/Cavin-4 and cavin family members form tissue-specific caveolar complexes

Autor: Michelle M. Hill, Piers J. Walser, Michele Bastiani, Susan J. Nixon, Paul F. Pilch, Mark P. Jedrychowski, Manuel A. Fernandez-Rojo, John F. Hancock, Kathryn N. North, Daniel Abankwa, Jørgen Vinten, Libin Liu, Harriet P. Lo, Steven P. Gygi, Michael R. Breen, Robert G. Parton, Robert Luetterforst

Publikováno v: The Journal of Cell Biology

Polymerase I and transcript release factor (PTRF)/Cavin is a cytoplasmic protein whose expression is obligatory for caveola formation. Using biochemistry and fluorescence resonance energy transfer–based approaches, we now show that a family of rela

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c43cdf65e11a6b26b5110d17a79b47e
https://doi.org/10.1083/jcb.200903053

Molecular Characterization of Caveolin-induced Membrane Curvature

Autor: James Rae, Brett M. Collins, Charles Ferguson, Natalya Leneva, Nicholas Ariotti, Michelle M. Hill, Piers J. Walser, Satomi Okano, Robert G. Parton, Dorothy Loo

Publikováno v: The Journal of biological chemistry. 290(41)

The generation of caveolae involves insertion of the cholesterol-binding integral membrane protein caveolin-1 (Cav1) into the membrane, however, the precise molecular mechanisms are as yet unknown. We have speculated that insertion of the caveolin sc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ead4c87f47f32b5b5272a0b12cc9b8ba
https://pubmed.ncbi.nlm.nih.gov/26304117