Zobrazeno 1 - 10 of 66 pro vyhledávání: '"J. W. van Kleef"'
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Effect of age on the clinical profile and systemic absorption and disposition of levobupivacaine after epidural administration
Autor: Anton G. L. Burm, J. W. Van Kleef, Mischa J. G. Simon, Rudolf Stienstra, B. T. Veering
Publikováno v: British Journal of Anaesthesia. 93:512-520
Pharmacokinetic and/or pharmacodynamic changes, which may occur with increasing age, could alter the clinical profile of the new local anaesthetic levobupivacaine. We investigated the effect of age on the absorption and disposition kinetics and the n
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fab6975b2c141ddf87ff737c512fb374
https://doi.org/10.1093/bja/aeh241
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4
Mortality associated with anaesthesia: a qualitative analysis to identify risk factors
Autor: H. H. A. J. M. Spoormans, J. J. De Lange, Diederick E. Grobbee, F. M. Werner, P. P. J. Touw, M. S. Arbous, J. W. Van Kleef, Anneke E. E. Meursing
Publikováno v: Anaesthesia. 56:1141-1153
From a prospectively defined cohort of patients who underwent either general, regional or combined anaesthesia from 1 January 1995 to 1 January 1997 (n = 869 483), all consecutive patients (n = 811) who died within 24 h or remained unintentionally co
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3b14edb373e21245cfdad1f9a536033
https://doi.org/10.1046/j.1365-2044.2001.02051.x
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6
Target-controlled infusion of alfentanil for postoperative analgesia: contribution of plasma protein binding to intra-patient and inter-patient variability
Autor: J. G. Bovill, M. C. O. Van Den Nieuwenhuyzen, A. A. Vletter, J. W. Van Kleef, F. H. M. Engbers, Anton G. L. Burm
Publikováno v: British Journal of Anaesthesia. 82:580-585
We have examined the influence of plasma protein binding on inter-individual and intra-individual variability in the effective postoperative analgesic concentration (EAC) of alfentanil and on the performance of the target-controlled infusion system u
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7c931df1c1fef9a3efbf2c77ab5ab1d
https://doi.org/10.1093/bja/82.4.580
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7
Pharmacokinetics of Prilocaine after Intravenous Administration in Volunteers
Autor: Rudolf Stienstra, Anton G. L. Burm, A. D. Van Der Meer, W. Olieman, J. W. Van Kleef, A. A. Vletter
Publikováno v: Anesthesiology. 90:988-992
Background Prilocaine exists in two stereoisomeric configurations, the enantiomers S(+)- and R(-)-prilocaine. The drug is clinically used as the racemate. This study examined the pharmacokinetics of the enantiomers after intravenous administration of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::12de72388dd916838cbb3eccef63e09a
https://doi.org/10.1097/00000542-199904000-00010
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8
The Epidural 'Top-Up' in Combined Spinal-Epidural Anesthesia
Autor: Anton G. L. Burm, Rudolf Stienstra, B. T. Veering, Albert Dahan, B. Z. R. Dilrosun-Alhadi, J. W. Van Kleef
Publikováno v: Anesthesia & Analgesia. 88:810-814
The reinforcement of anesthesia by an epidural "top-up" in combined spinal-epidural anesthesia may be explained by a dual mechanism: a volume effect compressing the dural sac and a local anesthetic effect. The purpose of our study was to investigate
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb0a9be2d85333ea6d040b461752ef56
https://doi.org/10.1097/00000539-199904000-00024
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9
Pharmacokinetics of the Enantiomers of Bupivacaine and Mepivacaine After Epidural Administration of the Racemates
Autor: W. Olieman, Rudolf Stienstra, Anton G. L. Burm, B. Zeppenfeldt, M. Mantel, J. W. Van Kleef, P. W. M. Zeijlmans, K. Groen
Publikováno v: Anesthesia & Analgesia. 86:361-366
We investigated the pharmacokinetics of the enantiomers of bupivacaine and mepivacaine after epidural injection of the racemate of each drug into six surgical patients. After epidural administration of either bupivacaine/HCl (115 mg) or mepivacaine/H
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e853945630e4173987dbeac1a1cb6bc
https://doi.org/10.1097/00000539-199802000-00027
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10
Target-controlled infusion of alfentanil for postoperative analgesia: a feasibility study and pharmacodynamic evaluation in the early postoperative period
Autor: Frank H. M. Engbers, A. A. Vletter, Anton G. L. Burm, M. C. O. Van Den Nieuwenhuyzen, J. G. Bovill, J. W. Van Kleef
Publikováno v: British Journal of Anaesthesia. 78:17-23
We have examined the feasibility of target-controlled infusion of alfentanil (TCIA) and the pharmacodynamics of alfentanil in the early postoperative period. Patients were allocated randomly to one of the three groups to receive balanced anaesthesia
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a532c6b39cf7ee478ff28d4b38ec17c
https://doi.org/10.1093/bja/78.1.17
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