Tricyclic antidepressants for major depressive disorder: a comprehensive evaluation of current practice in the Netherlands

Autor: Cornelis F. Vos, Rob E. Aarnoutse, Marijke J. M. Op de Coul, Jan Spijker, Mascha M. Groothedde-Kuyvenhoven, Raluca Mihaescu, Sonja J. W. Wessels-Basten, Jordy J. E. Rovers, Sophie E. ter Hark, Aart H. Schene, Marlies E. J. L. Hulscher, Joost G. E. Janzing

Publikováno v: BMC Psychiatry, Vol 21, Iss 1, Pp 1-11 (2021)

Abstract Background Traditionally tricyclic antidepressants (TCAs) have an important place in treatment of major depressive disorder (MDD). Today, often other antidepressant medications are considered as first step in the pharmacological treatment of

Externí odkaz: https://doaj.org/article/dc824c69f1c94f3ea0a85bae6f79c62a

A novel cryptic CBFB-MYH11 gene fusion present at birth leading to acute myeloid leukemia and allowing molecular monitoring for minimal residual disease

Autor: M. A. Veening, Shama L. Bhola, V. de Haas, J. W. Wessels, Marielle J. Wondergem, Pauline A. Merle, M. B. Mansur, Gertjan L. Kaspers, Pino J. Poddighe, W.A. Kors, A. M. Ford, Theresia M. Westers, A H Loonen

Publikováno v: Human Pathology: Case Reports, Vol 11, Iss, Pp 34-38 (2018)
Poddighe, P J, Veening, M A, Mansur, M B, Loonen, A H, Westers, T M, Merle, P A, Wessels, J W, de Haas, V, Kors, W A, Bhola, S L, Wondergem, M J, Ford, A M & Kaspers, G J L 2018, ' A novel cryptic CBFB-MYH11 gene fusion present at birth leading to acute myeloid leukemia and allowing molecular monitoring for minimal residual disease ', Human Pathology: Case Reports, vol. 11, pp. 34-38 . https://doi.org/10.1016/j.ehpc.2017.09.001
Human Pathology: Case Reports, 11, 34-38. Elsevier Inc.

Acute myeloid leukemia (AML) with the inv(16)/t(16;16) karyotype is associated with a favourable prognosis, showing longer periods of complete remission and high overall survival rates. Here we report a four year old girl, who presented with pallor,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::987b7642f8305a62abc10e4da2783a91
http://www.sciencedirect.com/science/article/pii/S2214330017300688

Detection of CBP rearrangements in acute myelogenous leukemia with t(8;16)

Autor: B. A. Van Der Reijden, Hartmut Döhner, J. H. F. Falkenburg, G.J.B. van Ommen, Fred Petrij, M Jotterand-Bellomo, J. G. Dauwerse, C. Higgins, Geoffrey C. Beverstock, Martijn H. Breuning, Rachel H. Giles, J. W. Wessels, Rosalyn Slater, A. Hagemeijer

Publikováno v: Leukemia. 11:2087-2096

The CREB-binding protein (CBP) is a large nuclear protein that regulates many signal transduction pathways and is involved in chromatin-mediated transcription. The translocation t(8;16)(p11;p13.3) consistently disrupts two genes: the CBP gene on chro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cab6b2194ae6556699208abb4d47e43c
https://doi.org/10.1038/sj.leu.2400882

Detection of monosomy 7 and trisomy 8 in myeloid neoplasia: a comparison of banding and fluorescence in situ hybridization

Autor: Ph. M. Kluin, R E Kibbelaar, H. Van Kamp, H.L. Haak, J. W. Wessels, Willem E. Fibbe, E.J. Dreef, J.W.R. Mulder, Geoffrey C. Beverstock

Publikováno v: Blood. 82:904-913

Fluorescence in situ hybridization (FISH) is a powerful tool for detection of numerical and structural chromosomal aberrations. We have compared conventional banding techniques and FISH for the detection of monosomy 7 (-7) and trisomy 8 (+8) in 89 pa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f1b8a30d074171e54586d506779255b8
https://doi.org/10.1182/blood.v82.3.904.904

Myeloid but not lymphoid cells carry the 5q deletion: polymerase chain reaction analysis of loss of heterozygosity using mini-repeat sequences on highly purified cell fractions

Autor: R. Willemze, J. E. Landegent, H. Van Kamp, R. Mout, M. J. P. L. Kroef, J. W. Wessels, W. E. Fibbe, R. P. M. Jansen, H.L. Haak

Publikováno v: Blood. 81:1849-1854

Interstitial deletions of the long arm of chromosome 5 are among the most characteristic abnormalities observed in myeloid disorders. To assess the lineage involvement of peripheral blood cells from patients with a 5q--anomaly, purified neutrophils,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c920929802005a02680ddf6497ceb1a6
https://doi.org/10.1182/blood.v81.7.1849.1849