Zobrazeno 1 - 10
of 383
pro vyhledávání: '"J. W. Watson"'
Autor:
J. W. Watson
Publikováno v:
Geographica Helvetica, Vol 26, Iss 1, Pp 31-33
No abstract availble
Externí odkaz:
https://doaj.org/article/86562d05127b482c8cc670f7bcc4772f
Publikováno v:
PLoS ONE, Vol 15, Iss 5, p e0233111 (2020)
Bangladesh exhibits the second highest rate of smokeless tobacco (SLT) product usage in the world, and this has been associated with the high upper aerodigestive tract cancer incidence in this country. The goal of the present study was to examine the
Externí odkaz:
https://doaj.org/article/4faeb1d15ca642b3a77cc6b922368d5e
Publikováno v:
PLoS ONE, Vol 15, Iss 6, p e0225044 (2020)
Cellular stress response mechanisms normally function to enhance survival and allow for cells to return to homeostasis following an adverse event. Cancer cells often co-opt these same mechanisms as a means to evade apoptosis and mitigate a state of c
Externí odkaz:
https://doaj.org/article/033a316359994377ab41cad556c7bac9
Autor:
Ross Jason Bindler, Christy J. W. Watson, Abram J. Lyons, Lillian Skeiky, Jamie Lewis, Michael McDonell, Philip Lazarus, Marian Wilson
Publikováno v:
Hospital pharmacy. 57(4)
Objective: To determine if a 2-day protocol measuring pharmacokinetic and pharmacodynamic characteristics can demonstrate drug-drug interactions when smoked cannabis is added to orally administered hydrocodone/acetaminophen combination products. Case
Honeycomb structures are frequently used as energy absorption devices in the automotive and aerospace industry. Many studies have been conducted to optimise these structures and improve crashworthiness behaviour. This paper attempts to improve the cr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13be3ca373051b7a6188421f2657faa8
https://dspace.lib.cranfield.ac.uk/handle/1826/19334
https://dspace.lib.cranfield.ac.uk/handle/1826/19334
Publikováno v:
Chem Res Toxicol
The UDP-glycosyltransferase (UGT) family of enzymes are important in the metabolism of a variety of exogenous substances including polycyclic aromatic hydrocarbons (PAHs), a potent class of environmental carcinogens. As compared to the majority of UG
Autor:
S. P. Chernenko, W. J. Llope, A. Cardenas, H. Long, R. Lednický, V. A. Nikitin, K. E. Shestermanov, A. Stolpovsky, R. S. Longacre, W. Christie, L. Kotchenda, H. Bichsel, P. Seyboth, V. Trofimov, Guy Paic, A. Chikanian, A. V. Brandin, S. S. Shimanskii, A. I. Kulikov, Masashi Kaneta, W. M. Zhang, L. C. Bland, Y. Panebratsev, R.Kh. Kutuev, Andrey Vasiliev, Joram Berger, T. Todoroki, Adam Ryszard Kisiel, J. B. Carroll, A. E. Yakutin, G. Igo, M. Oldenburg, H. J. Crawford, M. Castro, M. Calderon De La Barca Sanchez, G. Rai, J. W. Mitchell, N. Schmitz, Janet Elizabeth Seger, VL Rykov, B. D. Anderson, V. Petrov, E. Shahaliev, A. Boucham, T. J. Humanic, V. B. Dunin, A. C. Saulys, Z. Z. Xu, Q. Li, R. Witt, S. E. Vigdor, T. W. Henry, Christian Claude Kuhn, W. S. Deng, V. Ghazikhanian, Nikita Smirnov, I.A. Savin, M. Csanád, A. I. Pavlinov, F. Liu, M. B. Tonjes, J. W. Harris, B. E. Bonner, N. T. Porile, O. D. Tsai, J. L. Romero, Mirko Planinic, H. M. Spinka, C. E. Allgower, G. Eppley, S. Bekele, V. Morozov, Michael Kramer, M. Cherney, B. Lasiuk, E. Finch, Thomas Michael Cormier, R. Willson, D. G. Underwood, Michael W. Anderson, E. Gushin, P. Yepes, V. Eckardt, R. Ma, P. Nevski, J. H. Thomas, D. Hardtke, F. Laue, A. H. Tang, R. D. Majka, J. Pluta, L. Liu, V. M. Leontiev, Olivier Ravel, G. LoCurto, C. O. Blyth, E. Hjort, I. Zborovský, Yu A. Matulenko, M. Horsley, G. Skoro, B. Stringfellow, T. S. McShane, Rene Bellwied, C. P. Lansdell, R. E. Tribble, R.J.M. Snellings, Gerald W Hoffmann, J. N. Marx, B. Choi, J. G. Cramer, Thomas Dietel, Alexander Kovalenko, L. V. Nogach, A. P. Meschanin, Y. Fisyak, Ian Johnson, Christophe Pierre Suire, J. Sowinski, J. Schambach, D. Reichhold, T. J. M. Symons, T. Niida, A. Lebedev, M. M. de Moura, A. Szanto de Toledo, T. Pawlak, Morton Kaplan, P. Sorensen, G. Van Buren, Sevil Salur, Saurabh Pandey, A. Tai, T. W. Ludlam, J. Amonett, J. M. Nelson, V. Emelianov, D. Keane, W. Peryt, R. Stock, L. G. Efimov, D. Seliverstov, A. Schüttauf, G. S. Averichev, J. Porter, C. Roy, A. Klyachko, Vladimir Tikhomirov, P. Chaloupka, S. Trentalange, A. Ishihara, Yu Chen, Gregory Rakness, B. K. Srivastava, I. M. Vasilevski, F. Retiere, J. Gans, Boris Hippolyte, J. C. Dunlop, Zubayer Ahammed, M. J. LeVine, H. G. Ritter, A. S. Konstantinov, B. Norman, A. A. Kuznetsov, S. Y. Panitkin, E. Yamamoto, J. Engelage, David Lynn, J. G. Ma, J. Takahashi, M. A. C. Lamont, S. B. Nurushev, Z. Milosevich, N. G. Minaev, Sergey Voloshin, K. J. Foley, V. S. Shvetcov, Q. J. Liu, C. A. Whitten, J. Baudot, A. Rose, Y. V. Zanevski, S. Lange, S. J. Lindenbaum, Yu. Ivanshin, N. Xu, John N. Wood, M. Guedon, A. M. Poskanzer, A. M. VanderMolen, Russell Wells, J. M. Landgraf, M. Strikhanov, A. Billmeier, J. Putschke, J. W. Watson, A. Ogawa, Thomas A. Trainor, R. P. Scharenberg, Christina Markert, H. S. Matis, G. Odyniec, J. Sandweiss, Z. Liu, W. W. Jacobs, G. D. Westfall, H. Ward, L. S. Schroeder, S. V. Razin, L. Gaudichet, H. Zhang, Jay Roberts, Jinghui Yang, Malgorzata Anna Janik, C. L. Kunz, K. Krueger, C. F. Moore, C. Struck, M. Lopez-Noriega, I. Sakrejda, M. L. Miller, Fuqiang Wang, P. Szarwas, A. S. Hirsch, P. M. Jacobs, P. Kravtsov, C. Adler, E. G. Judd, Michael A. Thompson, Michal Sumbera, Jeffrey G. Reid, A. A. P. Suaide, E. Sugarbaker, S. R. Klein, V. Faine, J. Castillo, S. W. Wissink, J. E. Draper, H. Z. Huang, N.D. Gagunashvili, O. Barannikova, D. L. Olson, Sukalyan Chattopadhyay, T. J. Hallman, V. Perevoztchikov, K. Filimonov, A. A. Derevschikov, Marie Germain, V. I. Yurevich, A. N. Zubarev, M. Messer, P. Fachini, V. V. Belaga, Peter Graham Jones, Lee Stuart Barnby, F. Meissner, L. Didenko, M. Kopytine, J. Fu, M. Tokarev, K. Schweda, H. H. Wieman, J. Kiryluk, Rajarshi Ray, L. Lakehal-Ayat, W. A. Love, Vitaly Okorokov, Bernd Surrow, J. L. Klay, C. A. Gagliardi, A. Ridiger, T. Herston, R. V. Cadman, S. Heppelmann, D. Flierl, Frank Jm Geurts, L. Martin, J. P. Coffin, O. V. Rogachevski, V. A. Moiseenko, Marcelo Gameiro Munhoz, D. J. Prindle, E. J. Stephenson, M. A. Lisa, S. Margetis, O. A. Grachov, B. Erazmus, Gerd Joachim Kunde, D. Cebra, A. Bravar, Yu Melnick, J. Balewski, Claude Andre Pruneau, T. Ullrich, R. Zoulkarneev, V. Grigoriev, E. Potrebenikova, T. Ljubicic, H. Caines
Publikováno v:
Physical Review Letters. 127
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 49(12)
Exemestane (EXE) is a hormonal therapy used to treat estrogen receptor-positive breast cancer by inhibiting the final step of estrogen biosynthesis catalyzed by the enzyme aromatase. Cysteine conjugates of EXE and its active metabolite 17β-dihydro-E
Autor:
J. W. Harris, R. Willson, D. G. Underwood, D. Thein, R. V. Cadman, C. Roy, P. Seyboth, M. Kopytine, J. Fu, E. Gushin, P. Yepes, V. Eckardt, D. Reichhold, Jianhong Wu, Frank Jm Geurts, I.A. Savin, N. T. Porile, A. H. Tang, T. J. M. Symons, A. Klyachko, J. H. Thomas, M. Tokarev, C-Q. Li, P. Sorensen, M. Shao, G. Van Buren, S. P. Chernenko, Vladimir Tikhomirov, R. Witt, V. Trofimov, R. P. Scharenberg, Christina Markert, W. T. Waggoner, Yu A. Matulenko, M. Horsley, T. W. Henry, W. J. Llope, P. Chaloupka, V. Yu Khodyrev, B. K. Srivastava, J. C. Dunlop, J. Gans, H. S. Matis, Zubayer Ahammed, M. J. LeVine, S. K. Badyal, S. Trentalange, L. S. Schroeder, S. Bhardwaj, Boris Hippolyte, S. V. Razin, M. Calderon De La Barca Sanchez, H. H. Wieman, B. Stringfellow, L. Gaudichet, H. Long, Sukalyan Chattopadhyay, W. W. Jacobs, J. Lauret, M. S. Ganti, R.Kh. Kutuev, Joram Berger, J. E. Gonzalez, Bedangadas Mohanty, T. W. Ludlam, J. M. Nelson, A. Ridiger, G. S. Averichev, K. Schweda, Guy Paic, A. Chikanian, S. S. Shimanskii, Jay Roberts, S. Stanislaus, V. B. Dunin, S. Mahajan, Q. Li, M. Heinz, Michael Kramer, I. Zborovský, L. K. Mangotra, T. J. Hallman, Y. G. Ma, W. Peryt, D. K. Mishra, S. Heppelmann, D. Flierl, J. Porter, V. Ghazikhanian, J. L. Romero, R. Lednický, L. Martin, J. Engelage, John N. Wood, Premomoy Ghosh, J. M. Landgraf, M. Strikhanov, C. Perkins, T. Niida, A. Lebedev, M. M. de Moura, J. G. Cramer, R. Manweiler, T. S. McShane, Y. Fisyak, Ian Johnson, T. Todoroki, Adam Ryszard Kisiel, J. B. Carroll, Christophe Pierre Suire, H. J. Crawford, G. Wang, V. A. Nikitin, K. E. Shestermanov, A. Boucham, T. J. Humanic, D. Arkhipkin, S. Bekele, A. Ishihara, H. Jiang, Basanta Kumar Nandi, M. Guedon, A. M. Poskanzer, A. M. VanderMolen, Russell Wells, J. P. Coffin, O. V. Rogachevski, C. P. Lansdell, E. Sugarbaker, R.J.M. Snellings, H. Z. Huang, C. Struck, M. Lopez-Noriega, F. Meissner, J. Kiryluk, Rajarshi Ray, D. A. Morozov, J. L. Klay, M. Botje, A. Billmeier, G. Odyniec, J. Sandweiss, Z. Liu, R. Fatemi, C. O. Blyth, R. S. Longacre, P. Bhaskar, V. Perevoztchikov, K. Filimonov, Q. J. Liu, C. A. Whitten, L. Ruan, M. J. Mora-Corral, A. Rose, S. Lange, S. J. Lindenbaum, H. Ward, Sergey Voloshin, K. J. Foley, D. Seliverstov, J. Takahashi, M. A. C. Lamont, S. B. Nurushev, Z. Milosevich, X. L. Wang, B. I. Bezverkhny, S. Margetis, O. A. Grachov, X. Dong, S. K. Pal, A. Bravar, V. Grigoriev, E. Potrebenikova, V. V. Belaga, B. Erazmus, Gerd Joachim Kunde, D. Cebra, M. Estienne, E. Finch, A. Szanto de Toledo, T. Pawlak, A. Stolpovsky, L. Kotchenda, J. R. Adams, M. Castro, L. C. Bland, C. L. Kunz, K. Krueger, C. F. Moore, Y. Panebratsev, D. Grosnick, G. Rai, R. Picha, N. Xu, P. Filip, Debasish Das, G. D. Westfall, S. C. Phatak, A. Kumar, T. Ljubicic, M. Cherney, E. G. Judd, Thomas Michael Cormier, S. Das, P. Nevski, A. Gupta, B. Norman, Malgorzata Anna Janik, J. Baudot, Y. V. Zanevski, Saroj K. Nayak, Morton Kaplan, X. Z. Cai, Peter Graham Jones, Yu Melnick, H. Bichsel, Raghunath Sahoo, S. M. Guertin, D. P. Mahapatra, Yu Chen, M. Csanád, J. N. Marx, Mirko Planinic, P. A. Żołnierczuk, N.D. Gagunashvili, Michael W. Anderson, L. Liu, B. Choi, F. Du, S. Kabana, Olivier Ravel, Y. P. Viyogi, H. Caines, Sudhir Raniwala, Camelia Mironov, Michal Sumbera, A. A. P. Suaide, G. Renault, Thomas Dietel, Zhongyukun Xu, M. Potekhin, G. Igo, Alexander Kovalenko, L. V. Nogach, V. I. Kravtsov, M. R. Dutta Majumdar, M. Oldenburg, J. Zoulkarneeva, V. Faine, J. W. Mitchell, Z. P. Zhang, V. Petrov, J. Castillo, S. W. Wissink, Anand Kumar Dubey, L. Didenko, F. Retiere, A. S. Hirsch, P. M. Jacobs, J. Balewski, Rashmi Raniwala, Claude Andre Pruneau, P. Kravtsov, C. Adler, B. V. K. S. Potukuchi, David Lynn, J. E. Draper, N. G. Minaev, N. Schmitz, E. Shahaliev, T. Ullrich, R. Zoulkarneev, H. G. Ritter, Jeffrey G. Reid, D. Magestro, J. Putschke, J. W. Watson, E. Hjort, Gregory Rakness, H. M. Spinka, A. Ogawa, H. F. Chen, Shengli Huang, Thomas A. Trainor, G. Skoro, J. G. Ma, R. N. Singaraju, Marcelo Gameiro Munhoz, D. J. Prindle, Z. Z. Xu, A. P. Meschanin, S. R. Klein, Manish Sharma, M. A. Lisa, W. J. Dong, O. Barannikova, D. L. Olson, Nikita Smirnov, A. A. Derevschikov, Vitaly Okorokov, Bernd Surrow, Marie Germain, A. Tai, G. Sood, C. A. Gagliardi, J. Amonett, T. Herston, Madan M. Aggarwal, A. N. Zubarev, Fuqiang Wang, M. Messer, V. Emelianov, V. I. Yurevich, Frank Simon, P. Fachini, A. K. Bhati, D. Keane, S. Gronstal, Lee Stuart Barnby, R. Stock, L. G. Efimov, W. A. Love, D. D. Koetke, T. K. Nayak, B. E. Bonner, O. D. Tsai, B. Lasiuk, M. A. Vasiliev, Sevil Salur, Saurabh Pandey, W. Christie, A. I. Kulikov, Masashi Kaneta, W. M. Zhang, Andrey Vasiliev, Janet Elizabeth Seger, T. Kollegger, A. I. Pavlinov, F. Liu, M. B. Tonjes, V. Morozov, T. D. Gutierrez, D. Hardtke, F. Laue, R. D. Majka, J. Sowinski, Z. M. Wang, J. Schambach, Julien Faivre, A. V. Brandin, S. E. Vigdor, Christian Claude Kuhn, R. Ma, B. D. Anderson, H. Zhang, G. Eppley, I. Sakrejda, J. Pluta, M. L. Miller, L. Molnar, P. Szarwas, Rene Bellwied, R. E. Tribble, A. A. Kuznetsov, S. Y. Panitkin, Gerald W Hoffmann, E. Yamamoto, M. D. Trivedi
Publikováno v:
Physical Review Letters. 127
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 51(1)
The primary mode of metabolism of nicotine is via the formation of cotinine by the enzyme CYP2A6. Cotinine undergoes further CYP2A6-mediated metabolism by hydroxylation to 3-hydroxycotinine and norcotinine, but can also form cotinine