Zobrazeno 1 - 8
of 8
pro vyhledávání: '"J. W. Sperow"'
Publikováno v:
Journal of Biological Chemistry. 248:2062-2065
Analogs of PPi in which the bridge oxygen is replaced by imido, methylene, or α,ω-glycol linkages are not substrates for crystalline yeast inorganic pyrophosphatase. Apparent competitive inhibition of Mg2+-activated PPi hydrolysis is observed with
Publikováno v:
Nature. 253:561-563
TOLAZOLINE (2-benzyl-2-imidazoline), a peripheral vasodilator and adrenergic blocking agent used to treat peripheral vascular disease and (formerly) hypertension, has actions similar to those of histamine, including vasodilation, pressor responses in
Autor:
J W, Sperow, L G, Butler
Publikováno v:
The Journal of biological chemistry. 251(9)
The inert coordination complex of Cr(III) with PP1 (CrPP1) is not a substrate for yeast inorganic pyrophosphatase and does not inhibit the Mg2+-dependent activity of this enzyme. These results, when compared with the effects of CrPP1 on other enzymes
Publikováno v:
Arzneimittel-Forschung. 28(8a)
1-(2,6-Dimethylphenyl)-3-methylamidinourea hydrochloride (WHR-1142A, lidamidine hydrochloride) has been reported to be a potent antidiarrheal agent in laboratory animals. This study defines its effects on the cardiovascular and central nervous system
Publikováno v:
Arzneimittel-Forschung. 28(8a)
1-(2,6-Dimethylphenyl)-3-methylamidinourea hydrochloride (WHR-1142A), lidamidine hydrochloride), a novel antidiarrheal agent, inhibited contractile activity in isolated guinea pig ileum stimulated by acetylcholine, histamine, serotonin, dimethylpheny
Publikováno v:
Arzneimittel-Forschung. 28(8a)
1-(2',6'-Dimethylphenyl)-3-amidinourea hydrochloride (WHR-1142A, lidamidine hydrochloride), a potent, unique antidiarrheal agent, was tested for other pharmacological properties. It inhibited gastric acid secretion in both 4-h and 22-h pylorus-ligate
Publikováno v:
Arzneimittel-Forschung. 28(8a)
1-(2,6-Dimethylphenyl)-3-methyl-amidinourea hydrochloride (WHR-1142A, lidamidine hydrochloride) was shown to have potent antimotility, antidiarrheal and intestinal antisecretory activity in mice, rats and dogs. Antimotility activity was demonstrated
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