Výsledky vyhledávání - "J. W. Peacock"

Presence of a heterozygous substitution and its relationship to DT-diaphorase activity

Autor: M. C. Paterson, Andrew M. Rauth, J. W. E. Paterson, J. W. Peacock, B. L. Kuehl

Publikováno v: British Journal of Cancer

A point mutation in the mRNA of NADP(H): quinone oxidoreductase 1 (NQO1, DT-diaphorase) is believed to be responsible for reduced enzyme activity in the adenocarcinoma BE cell line. The present study examined nine cultured human non-cancerous fibrobl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd33af5c994b4e2ffc18db833cbf1729
https://doi.org/10.1038/bjc.1995.373

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Mutation of the endogenous p53 gene in cells transformed by HPV-16 E7 and EJ c-ras confers a growth advantage involving an autocrine mechanism

Autor: J W Peacock, Samuel Benchimol

Publikováno v: The EMBO Journal. 13:1084-1092

Rat embryo fibroblasts transformed with the HPV-16 E7 gene and the activated c-H-ras gene fall into two distinct phenotypic classes. At high cell density, clones of one class form colonies in methylcellulose supplemented with low serum; at low cell d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55f09a54e10552805101e732fb032bf2
https://doi.org/10.1002/j.1460-2075.1994.tb06357.x

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Inactivation of the cellular p53 gene is a common feature of Friend virus-induced erythroleukemia: relationship of inactivation to dominant transforming alleles

Autor: D G Munroe, J W Peacock, Samuel Benchimol

Publikováno v: Molecular and Cellular Biology. 10:3307-3313

The Friend erythroleukemia virus complex contains no cell-derived oncogene. Transformation by this virus may therefore involve mutations affecting cellular gene expression. We provide evidence that inactivating mutations of the cellular p53 gene are

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cd9c9ecaa6af1be536ef3962c4c2e35d
https://doi.org/10.1128/mcb.10.7.3307

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TCR activation inhibits chemotaxis toward stromal cell-derived factor-1: evidence for reciprocal regulation between CXCR4 and the TCR

Autor: J W, Peacock, F R, Jirik

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 162(1)

Stromal cell-derived factor-1 (SDF-1), a C-X-C family chemokine, is a potent T lymphocyte chemoattractant. We investigated the effects of T cell activation on the chemotactic response to SDF-1. Anti-CD3 Ab stimulation of either Jurkat T cells or muri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e0b7c0562817ef4002355a2175cb9d31
https://pubmed.ncbi.nlm.nih.gov/9886389

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Synergism between pairs of immortalizing genes in transformation assays of rat embryo fibroblasts

Autor: J W, Peacock, G J, Matlashewski, S, Benchimol

Publikováno v: Oncogene. 5(12)

A number of cellular and viral genes encode proteins that play a role in the establishment of normal cells in culture. In addition, these genes cooperate with activated ras genes to induce cellular transformation. We show that ras-dependent transform

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a95ecc55c07b460744a3497cab29e29f
https://pubmed.ncbi.nlm.nih.gov/2178238

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Aggregation attractant of the European elm bark beetle,Scolytus multistriatus

Autor: J. W. Peacock, Robert M. Silverstein, G. T. Pearce, R. A. Cuthbert, J. B. Simeone, Gerald N. Lanier, W. E. Gore

Publikováno v: Journal of Chemical Ecology. 3:429-446

The three components of theScolytus Multistriatus aggregation attractant-4-methyl-3-heptanol (1), α-multistriatin (2), and α-cubebene (3)-were collected from beetles and elm wood by aeration, solvent extraction of host tissue, or solvent extraction

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9ffb14ef9691c9a3e1d4ca89959dedc5
https://doi.org/10.1007/bf00988186

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