Zobrazeno 1 - 10
of 62
pro vyhledávání: '"J. W. L. Fielding"'
Publikováno v:
British Journal of Surgery. 89:1405-1408
BackgroundIn the surgical management of gastric carcinoma, regional lymphatic spread is of prognostic importance. The fifth edition of the Union Internacional Contra la Cancrum classification has been shown to be reproducible, practical and of signif
Autor:
Simon R. Bramhall, R C Stuart, John H. Scholefield, J. L. Whiting, P. D. Brown, M Baillet, M. T. Hallissey, Peter McCulloch, Gillian Tierney, J. W. L. Fielding, Tim Maughan, Robert E. Hawkins
Publikováno v:
British Journal of Cancer
This randomised, double-blind, placebo-controlled study was designed to evaluate the ability of the orally administered matrix metalloproteinase inhibitor, marimastat, to prolong survival in patients with non-resectable gastric and gastro-oesophageal
Autor:
M. T. Hallissey, N.R. Cruickshank, S.J. Needham, Richard T. Bryan, J.A. Young, J. W. L. Fielding, D.D. Moffitt
Publikováno v:
European Journal of Surgical Oncology (EJSO). 27:291-297
Aims Accurate staging of gastric, oesophageal and oesophagogastric cancer is essential to avoid unnecessary laparotomies in patients where only palliation is appropriate. This requires a multimodal approach utilizing endoscopy, computed tomography an
Publikováno v:
Scopus-Elsevier
British Journal of Cancer
British Journal of Cancer
The UK Medical Research Council (MRC) randomized trial of gastric surgery, ST01, compared conventional (D1) with radical (D2) surgery. Sample size estimation was based upon the consensus opinion of the surgical members of the design team, which sugge
Publikováno v:
Gastric Cancer. 2:226-229
BACKGROUND: Despite encouraging retrospective and non-randomized trials, two large prospective, randomized trials of D1 vs D2 resections show double the mortality in the D2 group, with no increase in long-term survival. However, the D2 resection stil
Autor:
David J. Kerr, M. T. Hallissey, A. Burton, Janet A. Dunn, M. J. S. Langman, J. W. L. Fielding, J. L. Whiting
Publikováno v:
British Journal of Cancer. 81:1356-1362
Cimetidine is thought to inhibit suppressor T-lymphocyte function and preliminary evidence from a randomized trial indicated that it might prolong survival for patients with operable and inoperable gastric cancer. The British Stomach Cancer Group con
Autor:
J. W. L. Fielding, J.L. Whiting
Publikováno v:
European Journal of Surgical Oncology (EJSO). 24:263-266
The role of radical surgery for early gastric cancer has become a topic of considerable debate. Despite excellent results from Japan and several retrospective and uncontrolled trials, results from two large prospective randomized trials appear to dem
Publikováno v:
British Journal of Surgery. 85:408-411
Background Screening by serology for Helicobacter pylori in young dyspeptic patients has been shown to be effective in reducing demand for endoscopy. H. pylori has been implicated in the causation of gastric cancer and the reported seropositivity rat
Autor:
D. C. Mangham, Lawrence S. Young, Hermann Herbst, K. M. Newbold, E. L. Jones, J. W. L. Fielding, Gary M. Reynolds, M Ito, D. C. Rowlands, M. T. Hallissey, Gerald Niedobitek
Publikováno v:
British Journal of Cancer
We have analysed 174 gastric carcinomas from the United Kingdom and from Japan for the presence of Epstein-Barr virus (EBV) using in situ hybridisation for the small EBV-encoded nuclear RNAs (EBERs). EBV was detected in the tumour cells in all of six
Publikováno v:
British Journal of Cancer. 66:943-950
A randomised trial of adjuvant chemotherapy vs placebo in operable stomach cancer recruited 249 patients from the West Midlands Region between 1976-1980. A Cancer Registry survey identified a further 1261 suitable concurrent cases. Trial patients wer