Výsledky vyhledávání - "J. W. Hubbard"

Plasma Levels of Fluphenazine in Patients Receiving Fluphenazine Decanoate Relationship to Clinical Response

Autor: T. Van Putten, G. Mckay, K.K. Midha, Manickam Aravagiri, Stephen R. Marder, E. M. Hawes, Jim Mintz, J. W. Hubbard

Publikováno v: British Journal of Psychiatry. 158:658-665

The levels of fluphenazine and fluphenazine sulphoxide in schizophrenic patients who were randomly assigned to receive either 5 mg or 25 mg of fluphenazine decanoate every two weeks were monitored. Patients treated with 25 mg of fluphenazine decanoat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36949b1d5a0e66c2d567a971225ae73c
https://doi.org/10.1192/bjp.158.5.658

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Dielectric anomalies due to grain boundary conduction in chemically substituted BiFeO3

Autor: Arun Kumar, Shojan P. Pavunny, James F. Scott, Shalini Kumari, Ram S. Katiyar, Gopalan Srinivasan, J. W. Hubbard, Carlos Rinaldi, Nora Ortega

Publikováno v: Journal of Applied Physics. 117:114102

This work was supported by the DOE Grant DE-FG02-08ER46526 and NSF (Fellowship EPS 01002410). N. Ortega acknowledges financial support from the NSF-RII Grant R10701525 and Dr. Ashok Kumar was supported by DOD Grant W911NF-11-1-0204. The authors thank

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59e997bb68df1fccbdd6e8a08ad7f1c4
https://doi.org/10.1063/1.4915110

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Effects of food on the pharmacokinetics of methylphenidate

Autor: K K, Midha, G, McKay, M J, Rawson, E D, Korchinski, J W, Hubbard

Publikováno v: Pharmaceutical research. 18(8)

To test the hypothesis that the pharmacokinetics of d-methylphenidate (d-MPH) would be altered by food ingested before administration of an immediate release formulation (dl-MPH- IR) but not when food is ingested before a slow release formulation (dl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d33c480c1e4e6373f870379bfe2540a2
https://pubmed.ncbi.nlm.nih.gov/11587491

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Evaluation of the bioequivalence of highly-variable drugs and drug products

Autor: L, Tothfalusi, L, Endrenyi, K K, Midha, M J, Rawson, J W, Hubbard

Publikováno v: Pharmaceutical research. 18(6)

To establish procedures for the effective evaluation of bioequivalence (BE) for highly-variable drugs and drug products (HVD/P).2- and 4-period crossover BE studies with 24 subjects were simulated which generally assumed within-subject coefficients o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0cef12f2f28acb1a8c210c87892f8f8e
https://pubmed.ncbi.nlm.nih.gov/11934226

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The role of metabolites in a bioequivalence study II: amoxapine, 7-hydroxyamoxapine, and 8-hydroxyamoxapine

Autor: K K, Midha, J W, Hubbard, G, McKay, M J, Rawson, D, Hsia

Publikováno v: International journal of clinical pharmacology and therapeutics. 37(9)

Amoxapine is a dibenzoxazepine type tricyclic antidepressant. The mechanism of clinical action in patients is not well understood. In animals, amoxapine blocks the reuptake of norepinephrine and, to a lesser extent serotonin, into their respective ne

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d30accf3d311238db0c4d056988ad657
https://pubmed.ncbi.nlm.nih.gov/10507241

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The roles of depot injection sites and proximal lymph nodes in the presystemic absorption of fluphenazine decanoate and fluphenazine: ex vivo experiments in rats

Autor: J P, Luo, J W, Hubbard, K K, Midha

Publikováno v: Pharmaceutical research. 15(9)

The release and presystemic absorption of fluphenazine and its decanoate ester from intramuscular depots were investigated.Rats were sacrificed in groups of three at various times after injection of drug or prodrug in sesame oil. Muscle tissues at th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::339d1abd886da0189ed718c11e668073
https://pubmed.ncbi.nlm.nih.gov/9755905

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