Výsledky vyhledávání - "J. W. Gillard"

Predicting ambulance demand using singular spectrum analysis

Autor: J L Vile, J W Gillard, P R Harper, V A Knight

Publikováno v: Journal of the Operational Research Society. 63(11):1556-1565

This paper demonstrates techniques to generate accurate predictions of demand exerted upon the Emergency Medical Services (EMS) using data provided by the Welsh Ambulance Service Trust (WAST). The aim is to explore new methods to produce accurate for

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______645::85ad138ffd3851b4e3dc15cc864a6a34
http://www.palgrave-journals.com/jors/journal/v63/n11/full/jors2011160a.html

Zobrazit plný text záznamu

Stereochemical Aspects of the anti-HCMV Activity of Cytidine Nucleoside Analogues

Autor: Tarek S. Mansour, C. A. Evans, Jonathan Coates, A. R. Cimpoia, Haolun Jin, Alan D. Borthwick, P. J. Hunter, H. L. A. Tse, J. W. Gillard, D. J. Knight

Publikováno v: Antiviral Chemistry and Chemotherapy. 6:138-142

The remarkable selectivity of the β-L enantiomers of 2′,3′-dideoxycytidine analogues against the viral polymerases of HIV and HBV has stimulated our interest in targeting β-L enantiomers of anti-HCMV cytidine analogues. Indeed, Ara-C, FIAC and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5a0109d776a3d27d8fc5d146f8596999
https://doi.org/10.1177/095632029500600302

Zobrazit plný text záznamu

ChemInform Abstract: Structure-Activity Relationships Among a New Class of Antiviral Heterosubstituted 2′,3′-Dideoxynucleoside Analogues

Autor: Tarek S. Mansour, Haolun Jin, C. Ashman, E. Hooker, D. M. Dixit, Wei Wang, H. L. A. Tse, N. Cammack, Colleen A. Evans, J. W. Gillard, Bernard Belleau, Mark A. Wainberg, Horacio Salomón, A. R. Belmonte

Publikováno v: ChemInform. 26

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8042fa3567e321d99404875709e7f033
https://doi.org/10.1002/chin.199540260

Zobrazit plný text záznamu

Discovery of inhibitors of the 5-lipoxygenase activating protein (flap)

Autor: R N, Young, J W, Gillard, J H, Hutchinson, S, Léger, P, Prasit

Publikováno v: Journal of lipid mediators. 6(1-3)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ea2c0364c02b1e47772f73186d8a8bb9
https://pubmed.ncbi.nlm.nih.gov/8357984

Zobrazit plný text záznamu

Characterization of a 5-lipoxygenase-activating protein binding assay: correlation of affinity for 5-lipoxygenase-activating protein with leukotriene synthesis inhibition

Autor: S, Charleson, P, Prasit, S, Léger, J W, Gillard, P J, Vickers, J A, Mancini, P, Charleson, J, Guay, A W, Ford-Hutchinson, J F, Evans

Publikováno v: Molecular pharmacology. 41(5)

A binding assay has been developed to measure the affinity of leukotriene synthesis inhibitors for 5-lipoxygenase-activating protein (FLAP), using human leukocyte membranes as the source of FLAP and a radioiodinated leukotriene synthesis inhibitor, 1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::577877c3efdd24ef563e3c46b880c697
https://pubmed.ncbi.nlm.nih.gov/1588922

Zobrazit plný text záznamu

5-Lipoxygenase-activating protein is the target of a novel hybrid of two classes of leukotriene biosynthesis inhibitors

Autor: J A, Mancini, P, Prasit, M G, Coppolino, P, Charleson, S, Leger, J F, Evans, J W, Gillard, P J, Vickers

Publikováno v: Molecular pharmacology. 41(2)

An 18-kDa leukocyte membrane protein, termed 5-lipoxygenase-activating protein (FLAP), has recently been shown to be the target of two structurally distinct classes of leukotriene biosynthesis inhibitors. These classes of inhibitors are based on indo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5ea475bfaaa222e0c255045be02efdae
https://pubmed.ncbi.nlm.nih.gov/1538707

Zobrazit plný text záznamu

Correlation between expression of 5-lipoxygenase-activating protein, 5-lipoxygenase, and cellular leukotriene synthesis

Autor: G K, Reid, S, Kargman, P J, Vickers, J A, Mancini, C, Léveillé, D, Ethier, D K, Miller, J W, Gillard, R A, Dixon, J F, Evans

Publikováno v: The Journal of biological chemistry. 265(32)

Previous studies involving transfection of cDNAs for 5-lipoxygenase-activating protein (FLAP) and 5-lipoxygenase into osteosarcoma cells have shown that both these proteins are essential for leukotriene synthesis (Dixon, R. A. F., Diehl, R. E., Opas,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::71a1661b030461324a64ea5cb9ff5b56
https://pubmed.ncbi.nlm.nih.gov/2174053

Zobrazit plný text záznamu

MK886, a potent and specific leukotriene biosynthesis inhibitor blocks and reverses the membrane association of 5-lipoxygenase in ionophore-challenged leukocytes

Autor: C A, Rouzer, A W, Ford-Hutchinson, H E, Morton, J W, Gillard

Publikováno v: The Journal of biological chemistry. 265(3)

Recently, we have shown that ionophore activation of human leukocytes results in leukotriene synthesis and a translocation of 5-lipoxygenase from the cytosol to cellular membrane. This membrane translocation was postulated to be an important early ac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7e42553fa2a724d4dc6813635b490547
https://pubmed.ncbi.nlm.nih.gov/2104841

Zobrazit plný text záznamu

Biogenesis of Proteaceous Alkaloids

Autor: H.-M. Leow, J. Pusset, Th. Sevenet, I. R. C. Bick, M. Lounasmaa, J. W. Gillard

Publikováno v: Planta Medica. 41:379-385

A scheme is presented which outlines the possible mode of biogenesis of alkaloids so far reported from the proteaceous plants Bellendena montana and Agastachys odorata (both from Tasmania), Darlingia darlingiana and D. ferruginea (from Queensland) an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cec9ad79d5f7cdabe352d3437f3cab0f
https://doi.org/10.1055/s-2007-971730

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání