Zobrazeno 1 - 10
of 141
pro vyhledávání: '"J. W. Fountain"'
Autor:
Antoine, Rodolphe
Publikováno v:
Nanomaterials (2079-4991); Sep2023, Vol. 13 Issue 18, p2551, 3p
Publikováno v:
Genes, chromosomescancer. 22(2)
The cyclin-dependent kinase inhibitor 2A (CDKN2A), or p16INK4a, gene on 9p21 is important in the genesis of both familial and sporadic melanoma. Homozygous deletions and intragenic mutations of this gene have been identified in both melanoma cell lin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b97b5dab0bb5430828388de09f90e94b
https://pubmed.ncbi.nlm.nih.gov/9598804
https://pubmed.ncbi.nlm.nih.gov/9598804
Autor:
M L, Gonzalgo, C M, Bender, E H, You, J M, Glendening, J F, Flores, G J, Walker, N K, Hayward, P A, Jones, J W, Fountain
Publikováno v:
Cancer research. 57(23)
Methylation of the 5' CpG island of the p16 tumor suppressor gene represents one possible mechanism for inactivation of this cell cycle regulatory gene that is also a melanoma predisposition locus. We have investigated the potential contribution of s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5157c6a6f8e57bb607de21d38207e8b1
https://pubmed.ncbi.nlm.nih.gov/9393758
https://pubmed.ncbi.nlm.nih.gov/9393758
Autor:
J S, Wiest, W A, Franklin, J T, Otstot, K, Forbey, M, Varella-Garcia, K, Rao, H, Drabkin, R, Gemmill, S, Ahrent, D, Sidransky, G, Saccomanno, J W, Fountain, M W, Anderson
Publikováno v:
Cancer research. 57(1)
Cytogenetic and molecular studies have implied the presence of tumor suppressor genes (TSGs) on chromosome 9p that are critical in the development of lung and other cancers. The p16/CDKN2 gene, a cyclin dependent kinase inhibitor, is a well-defined T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9bb4a143c55f2fd0ce18b9a146af2c8b
https://pubmed.ncbi.nlm.nih.gov/8988029
https://pubmed.ncbi.nlm.nih.gov/8988029
Autor:
J F, Flores, G J, Walker, J M, Glendening, F G, Haluska, J S, Castresana, M P, Rubio, G C, Pastorfide, L A, Boyer, W H, Kao, M L, Bulyk, R L, Barnhill, N K, Hayward, D E, Housman, J W, Fountain
Publikováno v:
Cancer research. 56(21)
Although homozygous deletions of the cyclin-dependent kinase inhibitor 2 gene p16INK4a on 9p21 have been reported frequently in metastatic melanoma cell lines, and intragenic mutations within the p16INK4a gene have been detected in familial melanoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5ad9faeedfba984b7f5ca56d41d686e3
https://pubmed.ncbi.nlm.nih.gov/8895759
https://pubmed.ncbi.nlm.nih.gov/8895759
Autor:
N C, Dracopoli, J W, Fountain
Publikováno v:
Cancer surveys. 26
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5fb75c8100c744a67137361b3f0a9871
https://pubmed.ncbi.nlm.nih.gov/8783570
https://pubmed.ncbi.nlm.nih.gov/8783570
Autor:
J A, Reed, F, Loganzo, C R, Shea, G J, Walker, J F, Flores, J M, Glendening, J K, Bogdany, M J, Shiel, F G, Haluska, J W, Fountain
Publikováno v:
Cancer research. 55(13)
Sporadic and familial malignant melanoma susceptibility has been linked to defects in the chromosomal region 9p21. Recently, a putative 9p21 tumor suppressor gene, the cyclin dependent kinase inhibitor 2 (CDKN2) or p16 gene, has been shown to be dele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5b2d0cbbfb285b4bb9f89ee073ee8c27
https://pubmed.ncbi.nlm.nih.gov/7796391
https://pubmed.ncbi.nlm.nih.gov/7796391
Publikováno v:
Cancer research. 54(2)
Deletions of DNA on chromosome 9p21-22 are frequently observed in cells derived from melanomas, gliomas, non-small cell lung cancers, and acute lymphoblastic leukemia. The minimal deletion shared by the latter three cancers extends from the interfero
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c2d1d9100755f511b293ed737754792a
https://pubmed.ncbi.nlm.nih.gov/8275465
https://pubmed.ncbi.nlm.nih.gov/8275465
Autor:
E M, Petty, L H, Gibson, J W, Fountain, J L, Bolognia, T L, Yang-Feng, D E, Housman, A E, Bale
Publikováno v:
American journal of human genetics. 53(1)
Cutaneous malignant melanoma (CMM) is often familial, but the mode of inheritance and the chromosomal location of melanoma susceptibility locus are controversial. Identification of a 34-year-old woman with eight primary malignant melanomas, multiple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bdf73a1a4f87f9348ddc46116a129ce8
https://pubmed.ncbi.nlm.nih.gov/8317504
https://pubmed.ncbi.nlm.nih.gov/8317504
Autor:
A P, Albino, J W, Fountain
Publikováno v:
Cancer treatment and research. 65
Due to a variety of known and unknown control mechanisms, the human genome is remarkably stable when compared to most other species. The long latency periods of most solid tumors, during which the cell undergoes malignant transformation, are presumab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ef9c1daca5a81631da5b5285798efab0
https://pubmed.ncbi.nlm.nih.gov/8104022
https://pubmed.ncbi.nlm.nih.gov/8104022