Zobrazeno 1 - 10
of 17
pro vyhledávání: '"J. W. Constantine"'
Autor:
K. G. Pratt, R. M. Snider, K. P. Longo, J. A. Lowe, S. McLean, Heidi A. Woody, Dianne K. Bryce, Jon Bordner, Wesley Lebel, S. E. Drozda, T. F. Seeger, J. W. Constantine
Publikováno v:
Peptides ISBN: 9789401050050
Peptides
Peptides
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2973b61cebd6f32de38bc755904179aa
https://doi.org/10.1007/978-94-011-2264-1_311
https://doi.org/10.1007/978-94-011-2264-1_311
Publikováno v:
Postgraduate medicine.
Results of animal studies indicate that the hypotensive effect of prazosin is due to vasodilatation which is dependent on two discernible components of drug action: (1) direct relaxation of vascular smooth muscle and (2) interference with peripheral
Publikováno v:
Journal of cardiovascular pharmacology. 6(1)
Trimazosin is a quinazoline antihypertensive agent structurally related to the selective alpha 1-adrenoceptor blocker prazosin. Trimazosin has been shown previously to have less affinity for alpha 1-adrenoceptors than prazosin. In the present study w
Publikováno v:
European journal of pharmacology. 66(4)
Prazosin inhibited contractions of isolated electrically stimulated dog pulmonary artery preincubated with (-)-7-3H-norepinephrine, but had no effect on 3H-overflow, whereas yohimbine enhanced both responses. In pithed dogs the cumulative doses of yo
Autor:
J W, Constantine, I M, Purcell
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 187(3)
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 239(3)
Effects of the calcium channel blocker, nifedipine, were examined on the pressor and vasoconstrictor responses to stimulation of alpha-1 and alpha-2-adrenoceptors in chronically instrumented conscious dogs and Rhesus monkeys. Norepinephrine (NE), a m
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 208(3)
The time course of plasma concentrations of sublingually administered pirbuterol was investigated in anesthetized dogs; there was a dose-related increase in plasma drug concentrations which reached maximum values 1 hr or more after administration. In
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 192(2)
Certain members of a series of 1-aminotetraline derivatives reversed the epinephrine pressor response in dogs; this effect occurred with the R- but not the S-isomers. Studies with rabbit aortic strips indicated competitive blockade of the alpha adren
Publikováno v:
Advances in prostaglandin, thromboxane, and leukotriene research. 11
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 207(2)
Pirbuterol, 2-hydroxymethyl-3-hydroxy-6-(1-hydroxy-2-tert-butylaminoethyl)pyridine, is a new beta2 adrenergic agonist bronchodilator. Comparison of the relative potencies of pirbuterol, salbutamol and isoproterenol as relaxants of isolated guinea-pig