Zobrazeno 1 - 10
of 28
pro vyhledávání: '"J. Veyssiere"'
Autor:
Sébastien Moreno, Jean Mazella, A Khayachi, Marc Borsotto, Stéphane Martin, H. Moha Ou Maati, Morgane Roulot, Christelle Devader, J. Veyssiere, Catherine Heurteaux
Publikováno v:
British Journal of Pharmacology. 172:2604-2617
Background and Purpose We have described a novel antidepressant peptide, spadin, that acts by blocking the TWIK-related-potassium channel, type 1 (TREK-1). Here, we examined possible mechanisms of action of spadin at both molecular and cellular level
Autor:
Jean Mazella, Marc Borsotto, H. Moha Ou Maati, Catherine Heurteaux, Christelle Devader, J. Veyssiere
Publikováno v:
British Journal of Pharmacology. 172:771-784
Depression is a disease that is particularly frequent, affecting up to 20% of the population in Western countries. The origins of this pathology involve multiple genes as well as environmental and developmental factors leading to a disorder that rema
Autor:
Marc Borsotto, J. Veyssiere, Nasser Haddjeri, Ameni Kanzari, Hamid Moha ou Maati, Catherine Heurteaux, Guillaume Lucas, Céline Bourcier-Lucas
Publikováno v:
Brain Structure and Function. 221:21-37
This study investigates the mechanism of action of spadin, a putative fast-acting peptidic antidepressant (AD) and a functional blocker of the K(+) TREK-1 channel, in relation with the medial prefrontal cortex (mPFC)-dorsal raphé (DRN) serotonergic
Autor:
Hervé Quintard, J. Veyssiere, H. Moha Ou Maati, C. Gandin, B. Onteniente, Catherine Heurteaux, M Lazdunski, Marc Borsotto, Catherine Widmann
Publikováno v:
Cerebrovascular Diseases. 35:1-7
Background: Treatments for stroke and other brain injuries are limited. NeuroAiD has been shown to be beneficial in clinical studies. We reviewed the pharmacological effects of NeuroAiD on the normal and ischemic brain and neurons. Methods: In vivo a
Autor:
Fabien Labbal, M Lazdunski, J. Veyssiere, Hervé Quintard, Marc Borsotto, Catherine Heurteaux, C. Gandin, Catherine Widmann
Publikováno v:
Neuropharmacology
Neuropharmacology, Elsevier, 2011, 61 (4), pp.622-31. ⟨10.1016/j.neuropharm.2011.05.003⟩
Neuropharmacology, Elsevier, 2011, 61 (4), pp.622-31. ⟨10.1016/j.neuropharm.2011.05.003⟩
International audience; Global ischemia leads to damage in the hippocampal CA1 region and is associated with behavioral deficits. NeuroAid (MLC601 and MLC901), a Traditional Chinese Medicine is used in China for patients after stroke. We have investi
Autor:
Nicolas Glaichenhaus, Agnès Petit-Paitel, Carine Gandin, Catherine Heurteaux, Mariel Pietri, Joëlle Chabry, Nicole Zsürger, J. Veyssiere, Sarah Nicolas
Publikováno v:
Psychoneuroendocrinology
Psychoneuroendocrinology, Elsevier, 2015, 57, pp.72-83. ⟨10.1016/j.psyneuen.2015.03.017⟩
Psychoneuroendocrinology, Elsevier, 2015, 57, pp.72-83. ⟨10.1016/j.psyneuen.2015.03.017⟩
Environmental enrichment (EE) that combines voluntary physical exercise, sensory and social stimuli, causes profound changes in rodent brain at molecular, anatomical and behavioral levels. Here, we show that EE efficiently reduces anxiety and depress
Autor:
Jean Mazella, Thierry Coppola, Marc Borsotto, Catherine Widmann, J. Veyssiere, Catherine Heurteaux, H. Moha Ou Maati, Fabien Labbal, C. Gandin
Publikováno v:
Neuropharmacology
Neuropharmacology, Elsevier, 2012, 62 (1), pp.278-88. ⟨10.1016/j.neuropharm.2011.07.019⟩
Neuropharmacology, Elsevier, 2012, 62 (1), pp.278-88. ⟨10.1016/j.neuropharm.2011.07.019⟩
International audience; Despite several decades of research, current antidepressant (AD) treatments remain of a limited efficacy justifying the need to find new drugs. These drugs have to be more efficacious, more rapid and display lesser side effect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e94fd6d3ea666b4e0eb9901c35f0b57
https://hal.archives-ouvertes.fr/hal-00726322
https://hal.archives-ouvertes.fr/hal-00726322
Autor:
Fabien Labbal, J. Veyssiere, C. Gandin, Catherine Heurteaux, Christelle Devader, Rémi Peyronnet, Jean Mazella, Hamid Moha Ou Maati, Marc Borsotto
Publikováno v:
PLoS ONE
PLoS ONE, Public Library of Science, 2011, 6 (10), pp.e25602. ⟨10.1371/journal.pone.0025602⟩
PLoS ONE, Vol 6, Iss 10, p e25602 (2011)
PLoS ONE, Public Library of Science, 2011, 6 (10), pp.e25602. ⟨10.1371/journal.pone.0025602⟩
PLoS ONE, Vol 6, Iss 10, p e25602 (2011)
International audience; TREK-1 potassium channels are involved in a number of physiopathological processes such as neuroprotection, pain and depression. Molecules able to open or to block these channels can be clinically important. Having a cell mode
Publikováno v:
Annales Françaises d'Anesthésie et de Réanimation. 32:A127-A128
Autor:
J. Veyssiere, Jean Mazella, Marc Borsotto, Georges Gaudriault, Catherine Heurteaux, Hamid Moha Ou Maati
Publikováno v:
Psychopharmacology
Rationale Although depression is the most common mood disorder, only one third of patients are treated with success. Finding new targets, new drugs, and also new drug intake way are the main challenges in the depression field. Several years ago, we i