Zobrazeno 1 - 10
of 351
pro vyhledávání: '"J. Vatier"'
Publikováno v:
Alimentary Pharmacology & Therapeutics. 2:461-470
A model of an 'artificial stomach' has been constructed in order to take into account some of the parameters lacking in conventional in vitro antacid evaluation, namely the interaction between secretory flux and variation in emptying fluxes, the pres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f0c475d88986c8711cb32ef1ba3ba4f
https://doi.org/10.1111/j.1365-2036.1988.tb00719.x
https://doi.org/10.1111/j.1365-2036.1988.tb00719.x
Publikováno v:
International Journal of Pharmaceutics. 163:225-229
A computerized `artificial stomach' model capable 1) of measuring the pH both in gastric contents, using a combined glass electrode, and at its surface, using a surface microelectrode, 2) of simulating the gastric emptying regulation in regard to the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c0c46fa593e9bd751c4eb924df1948ba
https://doi.org/10.1016/s0378-5173(97)00372-4
https://doi.org/10.1016/s0378-5173(97)00372-4
Publikováno v:
Fundamental & Clinical Pharmacology. 10:144-150
We assessed the effects of pirenzepine (2 mg/kg per os) on gastric secretion and gastrin and histamine release in response to food and histamine dihydrochloride infusion in four dogs during 24 weeks of treatment and for 15 weeks after the end of trea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc029e95d6c833300c8ea3352318aaab
https://doi.org/10.1111/j.1472-8206.1996.tb00157.x
https://doi.org/10.1111/j.1472-8206.1996.tb00157.x
Publikováno v:
Journal of Pharmaceutical Sciences. 83:962-966
Interactions of cimetidine and ranitidine with aluminum-containing antacids and clay-containing gastric-protective drugs were analyzed in vitro by using an artificial stomach-duodenum model. The model reproduced near-physiologic conditions, taking in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::372fbb0bd9558ff6c7ccf568216bf28a
https://doi.org/10.1002/jps.2600830709
https://doi.org/10.1002/jps.2600830709
Autor:
Miguel J.M. Lewin, C. Vissuzaine, Michel Mignon, Jacques Benveniste, I. Sobhani, Y. Denizot, J. Vatier
Publikováno v:
Digestive Diseases and Sciences. 37:1583-1592
Platelet-activating factor (PAF) has been implicated in the pathogenesis of acute inflammatory and ulcerative diseases of the upper gastrointestinal tract. In the present study, we compared the gastric output of PAF and its precursors with gastric ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ff0154d5e3a56a82834296e654dddce
https://doi.org/10.1007/bf01296506
https://doi.org/10.1007/bf01296506
Publikováno v:
International journal of pharmaceutics. 182(1)
Drug interactions with diosmectite, a gastric-protective drug, were studied in vitro using an artificial stomach-duodenum model. The behavior of neutral and ionisable drugs with pKa values ranging between 2 and 8 was monitored to determine the physic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::127b59825200c8a1eaa8e11fccdd5e59
https://pubmed.ncbi.nlm.nih.gov/10332080
https://pubmed.ncbi.nlm.nih.gov/10332080
Publikováno v:
Fundamentalclinical pharmacology. 12(6)
In this overview, the methods for assessing antacid activity in vitro are surveyed, and the problems of their comparison with in vivo methods of evaluation are discussed. In vitro assessment is based on two types of method: static and dynamic. The st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bd6bfdf6ff039482eac99588d768af2
https://pubmed.ncbi.nlm.nih.gov/9818289
https://pubmed.ncbi.nlm.nih.gov/9818289
Publikováno v:
Gastroenterologie clinique et biologique. 21(11)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d3f6316989bc88317ae3094e3f39c97a
https://pubmed.ncbi.nlm.nih.gov/9587530
https://pubmed.ncbi.nlm.nih.gov/9587530